金纳米粒子

金纳米粒子的制备方法及在DNA检测中的应用

Gold Nanoparticles Preparation and Application in DNA Detection

金纳米粒子与单链DNA的相互作用

Interaction Between Gold Nanoparticles and ssDNA

pH值对硫醇修饰的金纳米粒子聚集态的影响

PH Effects on the Aggregation of Gold Nanoparticles Modified by 3-Mercaptopropionic Acid

基于C（60）结构的金纳米粒子合成物的非线性折射与光限幅

Nonlinear Refraction and Optical Limiting in the Nanocomposite Based on C_ ( 60 ) Structured System with Gold Nanoparticles

因此，可以利用金纳米粒子调节亚甲蓝与DNA的作用方式。

Therefore , the interaction made of MB with DNA can be adjusted by using gold nanoparticles .

为金纳米粒子在DNA检测、生物及医药等领域方面的应用提供了新的途径。

The gold nanoparticles prepared in this way make much prospect of DNA detection , biology and medicine .

第二部分：利用金纳米粒子标记的DNA适配子为探针测定凝血酶的共振光散射分析。

Part two : Study on the Resonance Light Scattering analysis to determine thrombin by using gold nanoparticle-labeled DNA aptamer as probe .

基于AFM纳米氧化技术的金纳米粒子定点组装

Site-selective Assembly of Gold Nanoparticles on Silicon Using AFM Nano-oxidation Technique

金纳米粒子膜的电化学合成及SERS活性分析金纳米粒子的电化学合成及光谱表征

Electrochemical Synthesis and Analysis of SERS Activity of Gold Nanoparticles Films

金纳米粒子特殊的物理及化学性质使其在化学、生物、医学等领域有广泛的用途，尤其在DNA检测中有重要的应用价值。

Peculiar physical and chemical properties of gold nanoparticles make them have wide applications in fields of chemistry , biology and medicine , especially in DNA detection .

金纳米粒子组装体系SERS化学增强的研究

Study of Chemical Enhancement in SERS from An Nanoparticles Assembly

自组装金纳米粒子薄膜SERS研究

SERS-Activity of Electrostatically Self-Assembled Films of Gold Nanoparticles

最后用三种表面活性剂分别结合这两种金纳米粒子，并测量结合后的TEM图、紫外可见吸收光谱以及表面增强拉曼散射光谱。

Third , used three surfactant combination with two metal nanoparticles , and measurements combined TEM 、 UV spectrum and SERS spectrum .

根据PEG分子的空间位阻、疏水性等解释了PEG分子量不同而获得不同粒径金纳米粒子的原因。

The cause of obtaining gold nanoparticle with different size is the different space effect and hydrophobic property of PEG .

在前期工作的基础上，我们改进了实验方法，研究了另一种灵敏度更高的基于金纳米粒子信号放大的流动注射化学发光法检测DNA特定序列的生物传感器。

A novel and sensitive flow injection chemiluminescence assay for the sequence specific DNA detection based on the signal amplification with nanoparticles was developed on the basis of our preceding work .

LB技术制备金纳米粒子单层膜

Formation of Langmuir-Blodgett Monolayer of Nano Gold Particles

水/正己烷界面上超声波介导组装金纳米粒子薄膜用作SERS基底

Sonication-mediated Film Assembly of Gold Nanoparticles at a Water / Hexane Interface Used as a SERS Substrate

发光金纳米粒子测定曲通X-100及其临界胶束浓度

Determination of Triton X-100 and Its Critical Micelle Concentration with Luminescence Gold Nanoparticles

我们使用DNA折纸术的方法在特定的位置设计一些订书钉链作为金纳米粒子的连接位点，并且将修饰巯基的DNA引物通过共价键与金纳米粒子连接。

We have used the DNA origami approach to engineer staple strands at selected sites for attachment of gold nanoparticles . The covalent attachment of thiol-modified DNA oligomers was used to functionalize gold nanoparticles .

同时本文也通过金属粒子尺度效应模型对金纳米粒子n、k进行了计算和分析，初步体现了纳米量级不同粒径金粒子的n、k值尺寸效应。

At the same time , we also calculated n and k value of gold nano-particles , which reflects the size effect of n and k value when gold particles diameter is different .

建立了一个利用不同分子量PEG制备一系列粒径为6~60nm金纳米粒子的光化学合成新方法。

A new photochemical method was proposed for the preparation of gold nanoparticles in size of 6-60 nm , using different molecular mass of PEG .

在不同条件下采用LB技术制备了金纳米粒子单层膜，并利用SEM对所得到的薄膜的表面形貌进行表征。

The monolayers of Au nanoparticles were prepared by means of LB technique under different conditions , then the monolayers were characterized by SEM .

自组装金纳米粒子薄膜具有明显的SERS效应，其中2双层薄膜的增强效应最强。

The self-assembled multilayer films of gold particles exhibited an SERS-effect , and the 2-bilayer films were of the strongest SERS-activity .

利用三维时域有限差分法对金纳米粒子的SERS活性与其尺寸以及入射光波长的关系进行模拟计算。

The three dimensional finite difference time domain ( 3D-FDTD ) method was employed to simulate the size dependent SERS activity .

三维时域有限差分法计算金纳米粒子尺寸与SERS活性的关联用三维时域有限差分法研究随钻声波测井仪器隔声体的设计

Size Dependent SERS Activity of Gold Nanoparticles Studied by 3D-FDTD Simulation Designing Isolator of Logging-While-Drilling Acoustic Tools Using Three-dimensional Finite-difference Time-domain Method

第四章主要定量研究金纳米粒子的近场耦合、激发光波长等因素对其SERS活性的影响。

In chapter four , we quantitatively studied the correlations between near-field coupling , excitation wavelength and SERS activity of gold nanoparticles .

一种DNA-金纳米粒子导电复合物被成功的制备并应用于癌胚抗原（CEA）的早期检测中。

The results of detection of carcinoembryonic antigen ( CEA ) indicated that the synthesized DNA-gold nanoparticles networks could be a possible candidate of detecting early cancer .

该方法不需要荧光标记，且金纳米粒子修饰简单，建立了一种简便快速且价格低廉的DNA突变的检测方法。

So we can detect single-base DNA mutation . This method does not need fluorescence labeling , and Au nanoparticles modification is simple . So we established one kind rapid , convenient and low-cost method for detection of DNA mutation .

TEM照片中同时观察到金纳米粒子周围的聚合物层，轮廓的大小与DLS结果相近。

The polymer shell surrounding the gold nanoparticles was visible in the TEM images with the size of the outline being close to the DLS result .

吸收峰红移及SERS效应与薄膜中的金纳米粒子间的电磁耦合作用有关。

Both the red shift of the plasmon absorption band and the SERS effect result from the interparticle interactions of gold nanoparticles within the films .