酮醇

基于酮醇酸还原异构酶KARI复合物晶体结构的三维数据库搜寻

3D-Database Searching Based on the Crystal Structure of Ketol-acid Reductoisomerase ( KARI ) Complex

靶向酮醇酸还原异构酶（KARI）抑制剂的设计、合成、生物活性及构效关系

Design , Synthesis and Biological Evaluation and Structure-Activity Relationship of Targeting Ketol-Acid Reductoisomerase Inhibitors

采用同样条件进行二次酶动力学拆分，得到ee值>98%的手性烯酮醇，总拆分收率23%。

The chiral cyclopentenone of > 98 % enantiomer excess was obtained by a second time enzymic kinetic resolution under the same conditions , and the total yield of the enzymic resolution was 23 % .

芽孢杆菌属的转酮醇酶（Transketolase，TKT）变异株可利用培养基中的D-葡萄糖，将其转化成D-核糖分泌于细菌培养基中。

Transketolase mutant of bacillus subtilis can produce D - ribose in medium using D - glucose as carbohydrate .

结果（1）农村孕妇硫胺素摄入量显著高于城市孕妇，红细胞转酮醇酶活性（TPP效应%）城乡之间差异无统计学意义；

Results Showed : ( 1 ) The intake of thiamin of the rural pregnant women was significantly higher than that of the urban pregnant women . And there was no significant difference in erythrocyte transketolase activity ( TPP effect % ) between the urban and rural .

酮醇酸还原异构酶（KARI）是植物和微生物体内支链氨基酸生物合成的关键酶之一，可以作为设计除草剂的靶标，通过抑制酶的活性中断支链氨基酸的合成使植物死亡，达到除草目的。

Ketol-acid reductoisomerase ( KARI ) is a promising target for the design of herbicides because it is another essential enzyme for the synthesis of branched-chain amino acids in plants and microorganisms yet absent in animals .

微波辐射下活性MnO2选择氧化苯甲醇合成苯甲醛转酮醇酶是磷酸戊糖途径的关键酶，催化二碳单元在酮糖（体）醛糖（体）的转移。

Synthesis of Benzaldehyde from Benzyl Alcohol by Selective Oxidation with Active MnO_2 Under the Microwave Irradiation Transketolase is the key enzyme of pentose-phophate pathway , catalyses transfer of a two-carbon fragment from a ketolase ( donor substance ) to an aldose ( acceptor substance ) .

在酮醇物质的量比为1∶1.5，催化剂用量2.0%，带水剂环己烷10mL，反应时间80min的条件下，环己酮1,3丁二醇缩酮的收率可达94.0%。

The yield of cyclohexanone 1 , 3-butanediol ketal was up to 94.0 % when molar ratio of cyclohexanone to 1 , 3-butanediol was 1 ∶ 1.5 , amount of catalyst was 2.0 % , water-carrying agent was 10 mL , and reaction time was 80 mins .

酮醇酸还原异构酶抑制剂的设计、合成及除草活性

Design , Synthesis and Herbicidal Activity of Ketol-acid Reductoisomerase Inhibitors

韦尼克脑病脑区选择性损害与转酮醇酶活性下降相关的实验研究

Decreased Activity of Transketolase is Related With Regionally Selective Damage of Brain Midline in Wernicke Encephalopathy

丙烯酮醇和丙烯酮乙酸酯对映体分析的气相色谱方法研究

Development of Gas Chromatographic Method for Chiral Analysis of Acrylic Ketone Alcohol and Acrylic Ketone Acetate

建立了基于手性毛细管柱直接测定丙烯酮醇和丙烯酮乙酸酯对映体含量的气相色谱法。

A gas chromatographic method was developed to directly determine the enantiomers of acrylic ketone alcohol and acrylic ketone acetate .

本文综述了葡萄浆果中的酚酸类、黄酮醇类、黄烷醇类、黄烷酮醇类、花色苷类等主要多酚化合物。

The main polyphenols compounds in grape berry such as phenolic acids , flavonols , flavanols , flavanonols , anthocyanins were reviewed in this paper .

探讨了磷钨酸对丁酮1,2丙二醇缩酮合成反应的催化活性，研究了酮醇摩尔比、催化剂用量、反应时间等因素对产品收率的影响。

Catalytic activity of phosphotungstic acid on synthesizing butanone 1,2-propanediol ketal was discussed , the factors influencing the synthesis were discussed and the best conditions were found out .

考察了芳香族氨基酸和维生素对转酮醇酶缺失的枯草芽孢杆菌生长以及D-核糖生产的影响。

In this study , effects of aromatic amino acids and vitamins on the growth of transketolase-deficient Bacillus subtilis and D-ribose biosynthesis were studied in chemically defined media .

考察了反应温度、氨醇比、酮醇比、水含量和停留时间对反应性能的影响。

The effects of reaction temperature , molar ratio of ammonia to methanol , composition of raw materials and residence time on the catalytic performances of the catalyst were studied .

转酮醇酶是磷酸戊糖途径的关键酶，催化二碳单元在酮糖（体）醛糖（体）的转移。

Transketolase is the key enzyme of pentose-phophate pathway , catalyses transfer of a two-carbon fragment from a ketolase ( donor substance ) to an aldose ( acceptor substance ) .

以H3PW12O40/TiO2为催化剂催化合成了环己酮1,2-丙二醇缩酮，探讨了H3PW12O40/TiO2对缩酮反应的催化活性，较系统地研究了酮醇物质的量比，催化剂用量，反应时间诸因素对产品收率的影响。

The catalyst H3PW12O40 / TiO2 was prepared . Cyclohexanone 1,2-propanediol ketal was synthesized from cyclohexanone and 1,2-propanediol in the presence of H3PW12O40 / TiO2.The factors influencing the synthesis were discussed and the best conditions were found out .

结果表明，用二苯甲酰甲烷的酮醇互变异构性质能够表征有序介质的微环境性质，确定表面活性物质的临界胶束浓度。

The results indicated that the properties of tautomerism of DBM could be applied to characterize the microenvironment al property of organized media , reveal the structural characteristics of micelle , and determine the critical micelle concentration of surfactant .