血栓调节蛋白

目的研究可溶性血栓调节蛋白（sTM）水平在急性肺栓塞（PE）中的意义。

Objective To determine the levels of soluble thrombomodulin ( sTM ) in patients with acute pulmonary embolism ( PE ), and evaluate sTM clinical significance .

血栓调节蛋白在成人及胎肺组织中的表达

Expression and localization of thrombomodulin in human fetal lung

血栓调节蛋白、活化蛋白C抵抗与脑梗死的相关性研究

Study on the Dependablity between TM , APCR and Cerebral Infarction

人血栓调节蛋白及各相关因素在蛋白C体外活化中的作用

Effect of thrombomodulin and related factors in protein C activation in vitro

用人血栓调节蛋白检测血浆蛋白C抗凝活性及其初步临床应用

Assay on protein C anticoagulant activity in human plasma by thrombomodulin and its clinical application

2型糖尿病患者血浆可溶性内皮细胞蛋白C受体和血栓调节蛋白的变化

Changes of plasma soluble endothelial cell protein C receptor and thrombomodulin levels in patients with type 2 diabetes mellitus

条带杂交mRNA定量分析及其在血栓调节蛋白基因表达研究中的应用

Quantitative analysis of mRNA by slot blot and its application to the study of gene expression of thrombomodulin

血栓调节蛋白和vonwillebrand因子作为核辐照引起内皮细胞损伤的标志

Thrombomodulin and von Willebrand factor as markers of radiation-induced endothelial injury

血管生成素1和血栓调节蛋白1在STZ鼠肾脏中的表达及其意义

The expression of the angiopoietin-1 and thrombomodulin-1 in the kidney of diabetic rats

目的研究血浆血栓调节蛋白（TM）水平与心脑、血管内皮细胞损伤和血栓形成的关系。

Objective To study the relationship between the level of thrombomodulin ( TM ) and the injury of endothelial cells and the formation of thrombosis .

利用hTM表达细胞株制备抗人血栓调节蛋白单克隆抗体

Preparation of Anti-hTM Monoclonal Antibody by Using hTM Expression Cell Line

目的探讨急性胰腺炎不同阶段血浆血栓调节蛋白（TM）、D-二聚体的变化及其临床意义。

Objective To study the levels of plasma thrombomodulin ( TM ) and D-dimer ( D-D ) and their clinical significance in acute pancreatitis at different stages .

C5a对血管内皮细胞表达血栓调节蛋白的影响

Effect of C5a with the Thrombomodulin Expression on Endothelial Cells in Vitro

目的探讨血栓调节蛋白（thrombomodulin，TM）基因启动子甲基化与冠心病（CHD）的关系。

AIM To investigate the relation between methylation of plasma thrombomodulin ( TM ) gene promoter and coronary heart disease ( CHD ) .

目的研究血栓调节蛋白（thrombomodulin，TM）在胚胎肺、正常肺组织及肺癌组织中的表达。

Objective To investigate the expression of thrombomodulin ( TM ) in fetal lung , normal adult lung tissue and lung cancer .

前言：目的：探讨血栓调节蛋白（TM）在多器官功能障碍综合征（MODS）中的表达及其意义。

Objective : To study the expression of thrombomodulin ( TM ) and its significance in the pathogenesis of multiple organs dysfunction syndrome ( MODS ) .

目的旨在初步探讨大鼠严重烧伤早期（伤后24小时）血栓调节蛋白、蛋白C和蛋白S的动态变化。

Objective This study was to investigate the characteristics of changes in thrombomodulin ( TM ) / protein C ( PC ) / protein S ( PS ) anticoagulant pathway in early stage ( 24 hours postburn ) in severely burned rats .

在术前、术后隔天检测血浆可溶性血栓调节蛋白（STM）和血管性血友病因子（vWF）含量。

Plasma soluble thrombomodulin ( STM ) and von Willebrand factor ( vWF ) levels were measured before operation and every other day after operation .

血栓调节蛋白（Thrombomodulin，TM）是反映血管内皮损伤较敏感的指标，血浆中TM升高见于多种内皮损伤性疾病。

Thrombomodulin ( TM ) has been suggested as a sensitive marker of endothelial cell injury . The plasma level of TM increases in many diseases with endothelial lesions .

本文对29例急性非淋巴细胞白血病（ANLL）患者的血浆血栓调节蛋白（TM）水平进行检测，发现ANLL组血浆TM水平比正常组明显升高。

The plasma concentration of thrombomodulin ( TM ) were measured in29 cases of acute non-lymphocytic leukemia ( ANLL ) . Plasma TM level significantly increased in ANLL patients .

结论大鼠严重烧伤早期血栓调节蛋白蛋白C蛋白S抗凝途径发生显著变化，它不仅是烧伤早期血管内皮受损的标志，而且可能参与了严重烧伤后血栓和DIC的形成。

Conclusion The TM / PC / PS anticoagulant pathway altered obviously in early burnt rats , which was not only the marker of the vascular endothelium damage but also involved in thrombosis and disseminated intravascular coagulation after burn injury .

两组患者分别在入院当时及治疗第2、5、7d用ELISA法检测血浆血栓调节蛋白（TM）及血管性血友病因子（VWF），并与正常者比较。

Plasma thrombomodulin ( TM ) and von Willebrand factor ( vWF ) were both measured with ELISA in all patients on admission to hospital and on the 2nd , 5th , 7th day respectively .

目的：研究慢性肾小球疾病的血浆和尿血栓调节蛋白（PTM和UTM）水平及其临床意义。

Objective : To study clinical significance and level of plasma and urine thrombomodulin ( FTM and UTM ) in chronic glomerular disease .

目的了解血栓调节蛋白（thrombomodulin，TM）在肝细胞癌（HCC）病人血浆中的水平，探讨TM与HCC门静脉癌栓形成及侵袭和转移的关系。

Objective To study the relationship between plasma thrombomodulin ( TM ) level and formation of portal vein thrombus in hepatocellular carcinoma ( HCC ), and explore new prognostic marker for recurrence and metastasis of HCC .

目的探讨2型糖尿病患者血浆中内皮细胞损伤标志物内皮素（ET-1）、血栓调节蛋白（TM）、血管性假血友病因子（vWF）水平变化与糖尿病血管病变的关系。

Objective To explore the relationship between the changes of markers to endothelium cell injury endothelins-1 ( ET-1 ), thrombomodulin ( TM ) and von willebrand factor ( vWF ) levels in type 2 diabetes patients .

方法运用ELISA或发色底物法对93例AL患者血浆PC活性和抗原（PC：A和PC：Ag）、血栓调节蛋白（TM）及蛋白S（PS）水平进行了检测。

Methods The activity and antigen level of PC ( PC : A and PC : Ag ), as well as thrombomodulin ( TM ) and Protein S ( PS ) were measured among 93 cases of AL using ELISA or chromogenic substrate assay .

目的：探讨血浆组织型纤溶酶原激活物（t-PA）及其抑制物（PAI-1）、血栓调节蛋白（TM）和血小板α颗粒膜蛋白-140（GMP-140）在急性脑梗死发病中的意义。

Objective : To study the effects of tissue-type plasminogen activator ( t-PA ), plasminogen activator inhibitor-1 ( PAI-1 ), thrombomodulin ( TM ) and platelet alpha granule membrance protein-140 ( GMP-140 ) in patients with acute cerebral infarction ( CI ) .

血浆血栓调节蛋白（TM）和纤溶酶原激活物抑制剂（PAI-1）均可反映血管内皮的功能，抑制纤溶活性，促进凝血，参与血管生成，增加视网膜血管通透性等，最终导致DR。

Both plasma thrombomodulin ( TM ) and plasminogen activator inhibitor-1 ( PAI-1 ) can reflect the function of endothelial cell , inhibit fibrinolysis , promote coagulation , participate in angiogenesis , increase retinal vascular permeability , which then resulted in the occurrence of DR at last .

出血性疾病患者的血浆血栓调节蛋白检测的临床意义

Clinical Significance of Plasma TM Concentration Detection among Hemorrhagic Disease Patients

人血栓调节蛋白基因的表达及转基因小鼠的建立

Expression of Human Thrombomodulin Gene and the Establishment of Transgenic Mice