脂溢性角化病

P21~（WAF1/CIP1）和细胞周期蛋白E在脂溢性角化病中的表达及意义

Expression and significance of P21 ~ ( WAF1 / CIP1 ) and Cyclin E in seborrheic keratosis

YAG激光治疗脂溢性角化病38例

Effect of YAG laser in treating seborrheic keratosis

CO2激光治疗多发性皮脂溢性角化病

Multiple seborrheic keratoses treated with CO_2 laser

Q开关Nd：YAG激光联合高能超脉冲CO2激光治疗脂溢性角化病

Combined treatment of keratosis seborrheica with Q-switch Nd : YAG laser and ultra pulsed CO_2 laser

目的：研究脂溢性角化病皮损组织中P21WAF1/CIP1和细胞周期蛋白E（CyclinE）表达和意义。

Objective To investigate the expression and significance of Cyclin E and P21 WAF1 / CIP1 in seborrheic keratosis .

Survivin和PTEN在脂溢性角化病中的表达及其意义

Expression and clinical significance of survivin and PTEN in lesions of seborrheic keratosis

色素痣和蓝痣患者的年龄小于脂溢性角化病和疣的患者，有显著性差异（p0.01）。

Patients with blue nevus and pigmented nevus were younger than patients with seborrheic keratosis and wart ( p0.01 ) .

结论：P21WAF1/CIP1和CyclinE过度表达与脂溢性角化病的发生发展密切相关。

Conclusion The over expression of P21 WAF1 / CIP1 and Cyclin E is closely related to the pathogenesis of seborrheic keratosis .

细胞周期素E、P21～（WAF1/CIP1）、PCNA在脂溢性角化病皮损中的表达研究

Expression of Cyclin E 、 P21 ~( WAF1 / CIP1 ) and PCNA in Seborrheic Keratosis Tissue and Its Biological Significance

CyclinE、Ki-67、EGFR及Bcl-2在脂溢性角化病中的表达及其意义

The Expression and Significance of CyclinE , Ki-67 , EGFR and Bcl-2 in Seborrheic Keratosis

结果：脂溢性角化病皮损组织P21WAF1/CIP1和CyclinE阳性表达率及表达强度均明显高于正常皮肤组织（P<0.05）；

Results The over expression rates of P21 WAF1 / CIP1 and Cyclin E in seborrheic keratosis were significantly higher than those of normal control tissues .

P21~（WAFI）和PCNA在脂溢性角化病皮损组织中的表达与意义

The Expression and Significance of P21 ~ ( WAFI ) and PCNA in Seborrheic Keratosis

局部5-ALA光动力疗法治疗脂溢性角化病的疗效观察

Efficacy of ALA-PDT in Treatment of Seborrheic Keratosis

除1例脂溢性角化病pRb蛋白阴性表达外，12例角化棘皮瘤，11例脂溢性角化病及10例正常皮肤中p16、p15及pRb蛋白均呈阳性表达；

Whereas positive expressions of them were observed in almost all 12 keratoacanthomas , 11 seborrheic keratoses and 10 normal epidermises except loss expressions of pRb in 1 seborrheic keratosis ;

目的：探讨细胞周期相关因子细胞周期素E（CyclinE）、P21~（（WAF1）/（CIP1））和增殖细胞核抗原（PCNA）在脂溢性角化病皮损组织中的表达和意义。

Objective : To investigate the expression and significance of Cyclin E , p2l ~ ( WAF1 / CIP1 ) and PCNA in seborrheic keratosis , the relationship of Cyclin E , P21 ~ ( WAF1 / CIP1 ) and PCNA in seborrheic keratosis .

方法选择鳞状细胞癌8例、基底细胞上皮瘤10例、Bowen病8例和脂溢性角化病12例，运用免疫组化方法观察肿瘤细胞中环氧化酶-2的表达。

Method The expression of COX-2 was detected by immunohistochemical staining of skin specimens from 10 cases of basal cell carcinoma ( BCC ), 8 squamous cell carcinoma ( SCC ), 8 Bowen ′ s disease ( BD ), 12 seborrheic keratosis ( SK ) and 10 normal volunteers .

脂溢性角化病皮损的表皮中TGF-βⅠ型和Ⅱ型受体表达下调

Downregulation of TGF - β receptors in epidermis of seborrheic keratosis

方法应用微波治疗仪治疗脂溢性角化病，6个月后观察疗效。

Methods Microwave instrument was used for treatment of seborrheic keratosis .

微波治疗脂溢性角化病231例疗效观察

Observation on the therapeutic effect of microwave on 231 keratosis patients

目的探讨脂溢性角化病的临床及组织病理学特点。

Objective To learn the clinicopathologic features of seborrheic keratosis .

目的探讨脂溢性角化病的临床病理特征及诊断要点。

Objective To study the clinicopathological features and diagnostic criteria of seborrheic keratosis .

转化生长因子-α在脂溢性角化病皮损中的表达

Expression of Transforming Growth Factor - α in Skin Lesions of Seborrheic Keratosis

而环氧化酶-2在脂溢性角化病中的表达与正常人皮肤的表达近似。

COX-2 expression in SK cells was similar to that of normal epidermal cells .

九种化学剥脱剂对猪皮肤早期组织学影响的实验观察化学剥脱和刮除术联合治疗脂溢性角化病

Research on skin chemical peeling Effects of chemical peeling and scraping on seborrheic keratosis

目的观察微波治疗脂溢性角化病的疗效，为临床治疗提供依据。

Objective To observe the clinical efficacy of microwave in treatment of seborrheic keratosis .

多发性脂溢性角化病并发基底细胞癌1例

A case of multiple seborrheic keratosis with basalioma

结果显示：（1）脂溢性角化病可发生于任何年龄；

It is proposed that ( 1 ) keratosis seborrhoeica can occur in any age ;

脂溢性角化病是一种常见病，但临床上易与多种疾病相混淆。

Keratosis seborrhoeica is very common lesion and easy to be confused with some other diseases .

调Q-开关翠绿宝石激光治疗脂溢性角化病121例临床疗效观察

Q-switched Alexandrite Laser in Treatment of Seborrheic Keratosis : Report of Clinical Effect of 121 Cases

黑色丘疹性皮病不应看作独立疾病，而是早期发生的脂溢性角化病。

Dermatosis papulosa nigra is not a independent disease but represent keratosis seborrhoeica at its early stage .