肝脂肪变性

熊胆粉对豚鼠肝脂肪变性的预防

The Preventive Effects of Bear Bile on Fatty Degeneration of Liver Cells in Guinea Pigs

目的探讨熊胆粉对高脂饮食豚鼠肝脂肪变性的预防及其作用机理。

Objective To determine whether bear bile could prevent fatty degeneration of liver cells caused by high fat diet and the mechanism .

HBV、高脂环境和肝脂肪变性之间的关系如何？

What is the relationship of HBV , high-fat environment and hepatic steatosis ?

HIV/HCV协同感染与HCV单独感染患者肝脂肪变性的患病率与意义

Hepatic steatosis in HIV / hepatitis C coinfection : Prevalence and significance compared with hepatitis C monoinfection

了解HCV核心蛋白在诱发肝脂肪变性中的分子学机制，对丙型肝炎相关性脂肪肝的病因学，预防和治疗等方面具有极大的促进作用。

Understanding the molecule mechanisms of HCV core protein induction hepatic steatosis may contribute to elucidate the etiology , prevention and treatment of HCV hepatic diseases .

疏肝健脾方药能改善NAFLD模型大鼠肝脂肪变性。

The soothing liver and invigorating spleen recipes can improve hepatocytes steatosis in rats with NAFLD .

慢性丙型肝炎氧化n-3多不饱和脂肪酸的原位检测：与肝脂肪变性的关系

In situ detection of oxidized n-3 polyunsaturated fatty acids in chronic hepatitis C : Correlation with hepatic steatosis

肝脂肪变性程度，正常组为0级，对照组Ⅰ级，TPN组Ⅳ级。

On the side of the degree of fatty degeneration in the liver , normal group was class 0 , while control group and TPN group , respectively , belong to class ⅰ and class ⅳ .

口服酸枣油或酸枣浸膏53天，可明显降低日本种雄性鹌鹑高脂模型的TC、LDL和TG，肝脂肪变性亦明显减轻。

Our experiments have shown that oral administration of Semen Ziziphis Spinosae oiI ( SZSO ) or Ziziphis Spinosae extract ( ZSE ) given to quails for 53 days can significantly reduce their TC , LDL and TG and markedly subdue the fatty degeneration in their livers .

慢性乙型肝炎肝脂肪变性相关因素的探讨

Investigation of the Chronic Hepatitis B Patients with Hepatic Steatosis of the Relevant Factors

结论供肝脂肪变性对原位肝移植后移植肝功能不良有直接影响；

Conclusion Steatosis of donor liver has direct influence on the poor graft function after orthotopic liver transplantation .

结论：肝脂肪变性引起肝窦狭窄和不规则，门脉压增高。

Conclusion : Liver steatosis can result in narrow and irregular liver sinus and increase the portal vein pressure .

柴胡、丹参复方组肝脂肪变性程度明显轻于模型组（P<0.01）。

The level of steatosis was notably slighter in treatment group than in model group ( P < 0.01 ) .

该药物有明显的降低血脂及改善肝脏脂肪变性的作用，对治疗高血脂症和预防肝脂肪变性的发生发展有积极意义。

The drugs significantly lower cholesterol and improve hepatic steatosis . Prevention and treatment of hyperglycemia in development of hepatic steatosis has positive significance .

结果熊胆粉能降低胆汁胆固醇浓度，提高胆汁胆汁酸浓度，缓解肝脂肪变性。

Results Bear bile could decrease the concentration of cholesterol in bile , raise the concentration of bile acid in bile and relieve fatty degeneration of liver .

将供者性别、年龄、供肝脂肪变性程度及供肝是否切取肝中静脉作为影响术后肝脏再生和供受者术后肝功能恢复的影响因素进行分析。

The donor age , sex , liver steatosis and the middle hepatic vein if were harvested as the impact of donor and recipient liver regeneration and recovery of liver function factors were analyzed .

葛根组的肝组织脂肪变性和炎症浸润均较模型组显著减轻，肝组织γ-GT活性和TG含量显著低于模型组；

Pueraria can obviously alleviate hepatic steatosis and inflammation in model group .

行HE染色观察肝组织脂肪变性程度同时采用免疫组化染色法观察肝组织DPPⅣ的分布和表达情况。

To observe the degree of liver tissue steatosis by HE staining and the expressions of DPP ⅳ in liver tissue were examined using immunohistochemistry .

结果1.菊苣可显著抑制血清ALT、AST，减轻肝细胞脂肪变性及炎性细胞浸润，说明菊苣具有抑制肝细胞、肝损伤的作用。

C. intybus can significantly inhibit serum ALT , AST , fatty degeneration of liver cells and reduce the infiltration of inflammatory cells , that indicated it has the protection effect of the liver cells . 2 .

模型组肝细胞脂肪变性程度显著重于对照组（P0.05），运动组显著轻于模型组（P0.05），但仍然显著比对照组严重（P0.05）。

The hepatic steatosis of the model group was more severe compared with the control group ( P 0.05 ), the training group was obviously lighter than the model group ( P 0.05 ), but still more serious than the control group ( P 0.05 ) .

该学说认为，NAFLD的初次打击是指由胰岛素抵抗引起的肝细胞脂肪变性及肝内脂肪沉积，而在此基础上发生的氧化应激及脂质过氧化反应所导致的肝脏发生炎症、坏死为二次打击。

The first hit is fatty degeneration and lipid accumulation of liver cells induced by insulin resistance , and the second hit refers to the inflammation and necrosis of liver cells caused by oxidative stress and lipid peroxidation on the basis of the first hit .

结论：理气化痰祛瘀中药能明显改善高脂饮食诱导的大鼠肝组织脂肪变性，抑制大鼠肝组织NF-κBp65表达可能是其作用机制之一。

Conclusion : The Chinese prescription of regulating qi to dissipate blood stasis and phlegm can relieve the severity of fatty-liver in rats with fatty-liver induced by high-fat diet , down-regulating the expressions of NF - κ Bp65 maybe one of the mechanism in treating nonalcoholic fatty liver .

目的：对药物导致肝细胞脂肪变性模型进行研究。

AIM : To study the model of the drug-induced hepatocyte fatty degeneration .

病理模型组13天出现程度不同的临床症状，光镜下可见肝细胞脂肪变性、坏死；

Signs appeared in control group at 13 day .

病毒性乙型肝炎肝组织脂肪变性的相关因素分析

Analysing the Correlation in the Liver Tissue Fatty of the Patients with Hepatitis B

治疗组肝细胞脂肪变性程度无显著变化。

And the degree of hepatocyte steatosis did not change in the treatment group .

随着假小叶的形成和造模方法停止，肝脏病理结构变化趋于稳定；肝细胞脂肪变性尤为突出，与模型制作进程相平行。

Ballooning degeneration of liver cells was outstanding , and paralleled with model making course .

灶状肝细胞脂肪变性的超声诊断价值

Ultrasound Diagnosis of Focal Liver Fatty Degeneration

氧应激/脂质过氧化可能在肝组织脂肪变性后进一步发生炎症反应的过程中发挥重要作用；

Oxygen stress / lipid peroxidation may play an important role in formation of liver inflammation cell infiltration .

本实验成功制备了DL-乙硫氨酸诱导体外肝细胞脂肪变性，建立脂肪肝的动物体外模型。

In this study , it succeeded to made fatty liver in vitro model by DL-ethionine induced hepatocytes adipose degeneration .