羟脯氨酸

大鼠肝慢性损伤后血浆白蛋白mRNA和丙氨酸转氨酶及羟脯氨酸的变化

Changes of plasma mRNA , alanine aminotransferase and hydroxyproline in chronic liver damage of rats

1周后测量各组吻合口抗张力，用高效液相法（HPLC）测量吻合口组织羟脯氨酸含量。

Then measure the tensile strength and concentrations of hydroxyproline of colon stoma tissue with HPLC .

进行HE染色和电镜扫描观察与DNA含量、羟脯氨酸含量以及瓣叶生物力学检测。

Hematoxylin-eosin staining and scanning electronic microscopy were performed .

品种及杂交组合效应对育肥猪猪肉羟脯氨酸和pH值的影响

Effect of different breed and crossbred pigs with Hal ~ NHal ~ N on hydroxy - proline and pH in pork

先天性白内障晶体内，酪氨酸和羟脯氨酸含量明显高于正常对照组（P＜0.05）；

The values of tyrosin and hydroxy-proline in congenital cataractous lens aged 50 days were significantly higher than that of normal group ( P0 . 05 ) .

维生素K缺乏组动物尿钙、尿羟脯氨酸排出增高，提示维生素K缺乏导致骨分解代谢增强；

Vitamin K deficiency led to the high levels of urinary calcium and hydroxyapatite excretion , suggesting an increase of bone absorption .

尿羟脯氨酸（HOP）的含量。

The content of urinary hydroxyproline ( HOP ) .

照射后4个月和6个月两个时间点对各组的肺组织羟脯氨酸（HP）含量及肺病理形态变化（光镜和电镜）进行研究。

Pulmonary fibrosis was evaluated by lung hydroxyproline ( HP ) content and histological observation ( LM and EM ) .

30%酒精组股骨干重变化不大，骨羟脯氨酸含量有下降趋势，骨钙、磷仍增加（P0.05）；

In 30 % ethanol group , bone hydroxyproline tended to decrease but bone calcium , and phosphorus still increased ( P0.05 ) .

羟脯氨酸含量和型胶原RNA的表达水平。

The liver pathological and ultrastructural change , the content of rat liver hydroxyproline and the type ⅰ collagen RNA expression were observed .

结果：青年对照组，阳性对照组和茯苓高剂量组大鼠皮肤的羟脯氨酸含量均高于老年空白组（p＜0.05）。

Results : The content of HPY in the skin of Young Control Group , Positive Control Group and High-Poria-Dosage Group are higher than that of Old Control Group ( p < 0.05 ) .

Graves病患者骨密度与血AKP、尿羟脯氨酸的变化

Changes or Bone Mineral Density , Serum AKP and Urine Hydroxyproline in Graves ′ Disease

背部羟脯氨酸（HP）含量BHT组明显高于UV照射组，而腹部真皮羟脯氨酸含量各组均无差别。

The contents of dermis hydroxyproline in BHT + UV group are significantly higher than those in UV + irradiation group .

37℃4h后，用羟脯氨酸试剂盒测定各标本的胶原降解量。

The amount of degraded collagen of each sample was determined with hydroxyproline assay kit .

以心肌细胞中MT含量、血流动力学指标、心肌组织羟脯氨酸（HP）含量、内皮素（ET）含量作为观察指标。

Such index , including MT content , the recovery of hemodynamics , hydroxyproline ( HP ) and endothelin ( ET ) content were tested .

每2周观察组织学、过氧化及抗氧化指标MDA、SOD，羟脯氨酸含量等，评价光老化造模效果。

Observe the histological appearance , peroxide and antioxidant indexes of MDA / SOD , hydroxyproline contents every two weeks to evaluate the effects of photoaging model .

扫描电镜和羟脯氨酸分析表明更多的胶原被固定到了预先处理的CMC微载体上。

Scanning electron microscopy and hydroxyproline analysis revealed that larger amount of collagen was immobilized on the CMC-MC with initial treatment .

虫草对肺纤维化肺组织羟脯氨酸的表达影响：在各个时间点，M组羟脯氨酸含量最高，N组含量最低。

The effect of cordyceps sinensis on pulmonary fibrosis lung : at each point of time , the model group has the highest content of hydroxyproline , while the normal group has the lowest .

目的：探讨抗代谢药物丝裂霉素C（mitomycinC，MMC）对实验性椎板切除术后硬膜外瘢痕组织中羟脯氨酸（HOP）含量的影响。

Objective : To study the effect of mitomycin C , an anti-metabolic drug , on content of Hydroxyproline in the epidural scar tissue of experimental post-laminectomy .

用氯氨T法分析肺成纤维细胞总羟脯氨酸含量，并用抗TNF抗体和IFNγ进行成纤维细胞增殖和胶原合成抑制试验。

The hydroxyproline of fibroblast was analysed with chloramine-T and inhibiting assay of fibroblast proliferation and collage synthesis were carried out by using Unti-TNF antibody and IFNr .

检测肝组织羟脯氨酸（Hyp），明胶酶图法观察组织MMP-2、MMP-9活性表达。

Detect the Hyp of liver tissue , and observe the activity expression of MMP-2 , MMP-9 by gelatinase picture .

结论纳米SiO2较常规SiO2粉尘致肺脏脏器系数和羟脯氨酸含量增加的程度轻。

Conclusions The increase of lung / body coefficient and lung hydroxyproline was less in SiO 2 nanoparticles than that of normal SiO 2 .

耐羟脯氨酸（HYP）愈伤组织变异系的筛选；

Selection of Hyp-resistant variants ;

其作用优于Estradiol单纯提高胎鼠头盖骨中Ca的含量，而对骨的干重和羟脯氨酸含量无显著影响；

Its potency is greater than that of estradiol , which only increases calcium content in fetal rat calvaria but has no significant effects on dry weight and hydroxyproline content .

肌肉中羟脯氨酸含量与肌肉嫩度负对应，SOD活性与肌肉品质正对应，是表达不同品种鸡肌肉品质的有意义指标。

The content of OH-proline was negative correlated with muscle tenderness and the activity of SOD was positive correlated with meat quality . Both of them are meaningful indexes for meat quality .

研究了三个不同剂量的He－Ne激光照射对骨折愈合过程中血清羟脯氨酸浓度的影响。

The effects of three levels of energy density He Ne laser on the concentration of serum hydroxyproline in the Process of rabbit fracture healing were studied .

结果：EN/GH组吻合口破裂压力、抗张力强度和羟脯氨酸含量明显高于对照组和EN组，组织学结果表明，EN/GH组组织愈合较好。

Results : Anastomotic bursting pressure , anastomotic breaking strength and hydroxyproline content in EN + GH group were higher than that in control and EN groups .

结果C组和D组心肌羟脯氨酸含量及间质光密度和胶原线密度均低于A组（P<0.01），间质体密度高于A组（P<0.01）。

Results The content of cardiac muscle hydroxyproline , stroma light density and collagen length density in group C and group D were all lower and stroma volume density was higher than that in group A ( P < 0.01 ) .

用四唑盐（MTT）法检测细胞增殖情况，用碱性磷酸酶（ALP）试剂盒检测ALP活性，用细胞免疫实验检测细胞外基质中羟脯氨酸浓度，观察细胞胶原蛋白的合成分泌。

Cell proliferation was measured by MTT tese while activity of alkaline phosphatase ( ALP ) and hydroxyproline concentration in cell matrix was checked by ELISA .

结果：1.动物实验：生肌玉红膏组创面愈合率、愈合速度、创面肉芽微血管密度（MVD）、羟脯氨酸含量均高于对照组凡士林纱布组，结果有统计学差异（P0.01）。

Animal experiments : The Healing rate , MVD , and HYP of SHENG JI YU HONG ointment group are higher than the group of Vaseline gauze .