栀子苷

HPLC法测定清开灵胶囊中栀子苷的含量

Determination of Geniposide in Qingkailing Capsule by HPLC

含量测定：采用HPLC法对银天颗粒中的绿原酸和栀子苷的含量进行测定，确定其含量限度。

Content determination : the content of chlorogenic acid and geniposide in Yin Tian granules were determined by HPLC .

方法以HPLC法测定不同粉碎粒度样品中栀子苷的含量为指标，比较了粉碎粒度对栀子苷提取率的影响。

Methods The effects of extraction particle size was studied by determining the gardenoside content in the extract by HPLC .

以栀子苷标示栀子总环烯醚萜苷，采用HPLC法测定其含量，作为工艺筛选时的评价。

In this paper jasminoidin is used to signal total iridoid glycoside of Cape Jasmine Fruit , and the contents were determined by HPLC method for evaluation of technology screening .

胆酸、栀子苷及配伍对大鼠缺血再灌注脑组织TNF-α、IL-1β和ICAM-1含量的影响

Effect of Cholic Acid and Jasminoidin on Contents of TNF - α, IL-1 β and ICAM-1 in Rat Brain with Injury of Cerebral Ischemia and Reperfusion

结论树脂D301可用作栀子苷的精制方法。

Conclusion Resin D301 can be used to refine geniposide .

结论D301R型大孔树脂用作栀子苷的分离效果较好。

Conclusion D301R macroporous resin is effective to separate the gardenoside .

结论：HPD-100、HP-20对栀子苷有较强的吸附能力，极好的解吸率，其纯化产物栀子苷含量高，是精制栀子苷的良好吸附剂。

Conclusion : HPD-100 and HP-20 has better absorption ability and best desorption rate . They are good absorbent for the purification of jasminoidin . The contents of products purified with them are high .

细胞免疫荧光法结果显示与免疫蛋白印记法基本一致。结论：1.通络救脑注射液及其有效组分栀子苷、三七总皂苷均可通过抗氧化损伤作用有效减轻MVEC拟缺血损伤，提高细胞活性。

Immunofluorescence results are consistent with the immunohistochemical Western blot method . Conclusion : 1 . TongluoJiu ' naoinjectionfluid and effective components Geniposide and PNS can be effective in reducing ischaemic damage to MVEC due to oxidative stress , therefore improving cell activity .

样品处理采用固相萃取法，流动相为乙腈：磷酸盐缓冲液：水（15：5：85），检测波长：栀子苷240nm，芍药苷232nm。

The mobile phase for serum sample consisted of a mixture of acetonitrile : PBS : water ( 15 : 5 : 85 ) . The UV detector was set at 240 nm and 232 nm respectively .

高效液相色谱法测定蒙药如达-6中栀子苷的含量

Determination the Content of Geniposide in Mongolian Drug Ruda-6 by HPLC

目的优选分离栀子苷的大孔树脂。

Object To optimize the macroporous resin for separating gardenoside .

栀子苷乳酸-羟乙酸共聚物微球的制备及其性质研究

Preparation and characterization of geniposide loaded poly ( lactic-co-glycolic acid ) microspheres

尿塞通糖衣片、薄膜衣片的体外溶出度考察黄芩清肺分散片中栀子苷的体外溶出度研究

Study on in Vitro Dissolution Rate of Niaosaitong Sugar-coated Tablets and Film-coated Tablets

栀子苷阻抑脑缺血损伤级联反应的作用环节探讨

Protective effect of jasminoidin on cascade of damage of cerebral ischemia in rats

结果：分离纯化出栀子苷单体28.5g。

Results : 28.5 g gardenoside were isolated .

目的建立珍珠清心口服液中栀子苷的含量测定方法。

OBJECTIVE To establish a method to determine geniposide in Zhenzhu Qingxin oral solution .

而黄芩苷、栀子苷可以显著减轻上述损伤。

It was also observed that baicalin and gardenoside could significantly alleviate this injury .

目的：建立高效液相色谱法测定复肾宁片的栀子苷含量。

Objective : To establish a determination method for Jasminoidin in Fushenning tablets by HPLC .

大孔吸附树脂对栀子苷精制纯化的研究

Purification of Jasminoidin with Macroporous Absorption Resin

目的：探寻复肾宁胶囊中栀子苷的含量测定方法。

Objective : To establish a method to determine the content of geniposide in Fushenning capsule .

结论：柱层析和重结晶方法是简单、速分离栀子苷的有效办法。

Conclusion : Silica gel column chromatography and crystallization are simple and rapid methods to isolate gardenoside .

对所得药渣，进一步以栀子苷提取率为指标，采用正交试验优化了水煎煮工艺参数。

The gruffs were further extracted with water optimized by orthogonal test with jasminoidin yield as index .

目的建立清肝调脂胶囊中栀子苷含量测定方法。

Objective To develop the RP-HPLC method to determine the content of berberine hydrochloricde in the Tiaozhiqinggan capsule .

方法使用壳聚糖作为澄清剂，考察壳聚糖絮凝澄清效果，主要成分栀子苷为作为含量考察指标，并与醇沉法作对比。

Methods The clarified effect of chitosan was investigated , the content of jasminoidin was determined , and compared with precipitated method by alcohol .

结果表明：国标中以栀子苷为对照品，用高效液相色谱法测定食品中的栀子黄色素不够合理。

The results showed that it was not reasonable to assay the gardenia yellow pigment with the standard control in food by high performance liquid chromatography .

栀子苷在大鼠小肠的吸收速率随浓度的增加而减小，提示药物的吸收机制除了被动扩散外，可能有主动转运和易化扩散因素；

Their absorption was first-order process besides the passive diffusion mechanism , and facilitated diffusion and active transport may also take part in the transport process .

同时进行了栀子苷含量的变化与主成分的多元相关分析，证实了矿质元素与中药功效之间存在相关性。

We also multi-analyzed the relationship between the content of gentiobioside and principal component , which confirmed that there were relationship between microelement and efficacy of herbs .

配方颗粒组方汤剂栀子苷、盐酸小檗碱、黄芩苷平均提取率依次约为传统汤剂相应成分平均提取率的70%，145%及123%。

The extration rates of geniposide , berberine hydrochloride and baicalin in refine granule decoction were 70 % , 145 % and 123 % of traditional decoction respectively .

解析液为75%乙醇，10倍药材量，流速10mL/mim，黄芩苷及栀子苷的解析率可达95%以上。

And a resolution solution of 75 % alcohol , a resin amount of 10 times that of the drugs and a flow rate of 10 mL / min.