扭体反应

结果：皮下注射（sc）RAN6mg/kg后35～45min及45～55min均可显著抑制小鼠醋酸扭体反应，抑制率分别为67.76%及69.55%。

Results : RAN 6mg / kg sc could significantly inhibit the writhing response induced by acetic acid after 35 ~ 45 min and 45 ~ 55min administrated in rats The inhibitory rates were 67.76 % and 69.55 % , respectively .

冰醋酸建立小鼠扭体模型，检测扭体反应抑制率；通过热板实验测定小鼠的痛阈值，计算小鼠痛阈提高百分率，观察平胃舒胶囊的镇痛作用。

The analgesia function of Ping-wei-shu Capsule was observed by testing the inhibition rate of writhing response with glacial acetic acid and pain threshold through hot plate experiment on mice .

应用热诱发小鼠疼痛反应模型和冰醋酸诱导小鼠扭体反应模型观察CCD对疼痛的抑制作用。结果CCD对疱疹病毒Ⅰ型的半数有效浓度为098g·L-1。

And heat induced pain response and acetic acid induced writhing in mice were employed to observe the analgesic effect of CCD .

天元克痛方可以显著减少醋酸所致疼痛小鼠的扭体反应次数（P＜0.05），明显延长光幅射热致痛小鼠的甩尾潜伏期（P＜0.05）；

Tianyuan Ketong prescription could notably decrease times of body-writhing induced by acetic acid in mouse ( P < 0 . 05 ), and prolong latency of tail-flick induced by radiant heat stimulation in rats ( P < 0 . 05 );

在剂量为0.1mg／kg小鼠体重时，SAPⅤ对由醋酸引起的小鼠扭体反应抑制率为70%。

At a dose of 0.1mg/kg body weight , SAP V inhibited the 70 % of the twisting action of the mice induced by acetic acid .

记录腹腔注射醋酸后15min内小鼠的扭体反应数。

The number of torsion response was recorded within 15 minutes after intraperitoneal injection of acetic acid .

按10g／kg剂量ig能显著降低醋酸所致小鼠扭体反应次数（p＜0.01），扭体抑制率为47.33%；

They ( 10g / kg , ig ) can markedly decrease frequencies of twisting reaction induced by aceti acid in mice ( p < 0.01 ), whose rate of the decrease is 47.33 percent .

结论：理气活血止痛法对催产素所致痛经大鼠扭体反应有镇痛作用，其机制与血浆βEP的作用有关。

Conclusions : The method of regulating Qi and activating blood has close correlativity to the mechanism of easing pain caused by oxytocin and increasing β EP in blood plasma on rats .

动物实验结果表明，痛风冲剂能明显减少小鼠扭体反应次数，且能明显提高小鼠痛阈值，与生理盐水组比较，有显著性差异（P0.05）。

The results of animal experiment indicated that gout granule could obviously reduce the number of mice torsion reaction and raise the pain threshold of mice . Compared with NS group , there was an obvious difference ( P0.05 ) .

方法：采用连续ig给药，观察抗痛经冲剂对抗缩宫素诱发的小白鼠扭体反应；

METHODS : Anti menorrhagia preparation was administered to mice by ig for 12 days and its antagonism of anti menorrhagia preparation against mouse writhing symptom induced by oxytocin was observed .

结果··：用药组的戒断综合积分、体重减轻情况及其对热刺激的痛阈值和出现的扭体反应次数与NS组比较，差异均有显著性意义（P＜0.01）。

Result : The total scores of abstinence symptoms , the body weight loss of morphine dependent rats and the pain threshold , the number of writhing of mice were compared with NS group 's , and the difference was significant ( P < 0.01 ) .

镇痛实验表明，BTK（52与104mg·kg－1）能明显延长小鼠热板实验的痛反应潜伏期，对小鼠扭体反应也有明显的抑制作用。

It was also showed that not only writhing reactions induced by acetic acid were decreased , but also the latency of hot plate could be enhanced in mice treated with BTK ( 52 and 104 mg · kg ￣ - 1 ) .

结果：26.6、13.3、6.65、3.33和1.66g/kg赤雹果（生药）各剂量均可显著减少ip酒石酸锑钾致痛引起的小鼠扭体反应的次数，（与盐水组比较：P<0.05~0.01）。

Results : FTDB ( crude medicinal materials ) of 26.6 、 13.3 、 6.65 、 3.33 、 1.66g/kg all markedly reduced the times of writhing induced by ip antimony potassium tartrate in mice ( P < 0.05-0.01 vs NS group );

结果：①0.10mg/g，0.15mg/g拳参水提取物对醋酸诱发小鼠扭体反应有非常显著的镇痛作用，与对照组比较，差异有非常显著性意义（P0.01）。

RESULTS : ① PBL extract of 0.10 mg / g and 0.15 mg / g had very significant analgesic effect on the writhing reaction the mice induced by acetic acid as compared with the control group ( P 0.01 ) .

皮下注射小檗碱明显减少醋酸性小鼠扭体反应次数，半数有效量为3.5mg/kg，仅在皮下注射8mg/kg的大剂量时，对热板法实验表现出镇痛作用。

Berberine sulfate ( Ber ) given subcutaneously , significantly decreased acetic acid & induced writhing frequency in mice . The median effective analgesic dose ( ED_ ( 50 )) of Ber was found to be 3.5 mg / kg .

减少醋酸所致小鼠扭体反应次数。

The writhing times of mice induced by acetic acid decreased .

主要观察指标：①小鼠扭体反应次数。

MAIN OUTCOME MEASURES : ① Times of twisting - body reaction ;

对抗酒石酸锑钾引起小鼠的扭体反应；

Resisting reaction of rat spraining body caused by antimony potassium tartrate ;

能抑制醋酸诱发的小鼠扭体反应，提高小鼠热板痛阈。

It also enhanced the hot plate threshold in mice .

均能显著抑制07%醋酸引起的扭体反应。

Dose significantly inhibited the writhes induced by 0 7 % acetic acid .

女金胶囊能明显抑制醋酸诱发小鼠扭体反应的发生。

Nujing capsule inhibited the torsion reaction of the mice caused by acetic acid .

采用乙酸致小鼠扭体反应，观察亚砷酸注射液的镇痛效果。

Observation of the analgesic effects of AA injection on acetic acid-caused mouse writhing .

药物所致小白鼠扭体反应主要观察指标：①小鼠扭体反应次数。

A study on drug-induced writhing in the mouse main outcome measures : ① writhing times ;

氟哌啶醇与吗啡合用对醋酸导致小鼠扭体反应的影响

The Effects of Morphine Combined with Haloperidol on the Twisting Response of Mice Induced by Acetic Acid

试验结果表明：头痛宁滴丸的中剂量能明显减少冰醋酸所致小鼠产生扭体反应的次数。

Consequence indicate that , the middle dose can obviously decrease the time of mice 's twist by HAC .

结果狭叶荨麻根、茎、叶70%乙醇提取物及狭叶荨麻根水提取物能明显对抗二甲苯致小鼠耳廓肿胀，并显著抑制0.5%醋酸致小鼠扭体反应。

Results All test samples of Urtica angustifolia significantly inhibited dimethylbenzene-induced ear edema and acetic acid-induced writhing in mice .

同时设计了腹腔注射化学物质引起小鼠扭体反应的镇痛实验。

At the same time , we design relieving pain experiment which cause the mice twist by chemistry material .

结果乌红天麻种麻可显著提高小鼠的痛阈值和延长扭体反应的潜伏期，且呈剂量依赖性。

Result WHGS can increase the threshold of pain markedly in mice and the action depends on its dose .

方法采用醋酸诱发小鼠扭体反应和小鼠热板法。

Methods Analgesic effect was studied using experimental pain models induced by acetic acid and hot plate in mice .

结果筒鞘蛇菰甲醇提取物的正丁醇部位能显著提高小鼠热刺激的痛阀；且对小鼠醋酸扭体反应具有显著的抑制作用。

Results Then-BuOH fraction in methyl alcohol extract could significantly prolong the latencies of paw licking and decrease mice writhing .