异喹啉

一种新结构二聚异喹啉生物碱的NMR结构研究

The NMR Structural Study of a Novel Dimeric Isoquinoline Alkaloid

RP-HPLC同时测定紫金龙中4种异喹啉生物碱的含量

Simultaneous Determination of Four Isoquinoline Alkaloids in Root of Dactylicapnos scandens by RP-HPLC

pH校正最小二乘紫外分光光度法同时测定喹啉异喹啉和萘

Simultaneous determination of quinoline iso - quinoline and naphthalene by UV spectrophotometry and pH corrected least squares

四氢异喹啉衍生的异硫脲类化合物的合成及NOS抑制活性研究

Synthesis of isothioureas derived from tetrahydroisoquinoline and NOS inhibitory activity

N-酰基-1-苄基四氢异喹啉衍生物的合成和GABA转运蛋白抑制作用

Synthesis and GABA transporter inhibitory activities of N-acyl-1-benzyl tetrahydroisoquinoline derivatives

异喹啉季铵盐在盐酸中对A3钢的吸附及其缓蚀作用

Inhibition and adsorption behavior of isoquinoline quaternary ammonium salt for A3 steel in hydrochloric acid

用电化学方法测定了异喹啉及其衍生物的缓蚀效率，用HMO、CNDO法作量子化学计算表明：随着N原子负净电荷的减少，缓蚀效率提高；

Abstract The structure parameters and corrosion inhibition of isoquinolines were determined by HMO , CNDO and electrochemical methods .

方法：将1，2，3，4四氢异喹啉2基引入到硫脲和异硫脲结构中，测试合成的目标化合物的NOS抑制活性。

METHOD : 1,2,3,4-Tetrahydroisoquinol-2-yl are introduced into the structure of thioureas and isothioureas , the NOS inhibitory activity of the target compounds are measured .

异喹啉盐与环醚的Diels-Alder环加成反应

Diels-Alder cycloaddition of isoquinolinium salt with cyclic ethers

目的设计、合成新的1,2,3,4-四氢异喹啉衍生的异硫脲类化合物，并研究其对NOS抑制活性。

Aim To get some novel potent compounds with NOS inhibitory activity , a series of new compounds of isothioureas derived from 1,2,3,4-tetrahydroisoquinoline were synthesized .

小檗胺（Berbamine，BER）是从我国中草药小檗属（Berberis）植物中提取的一种双苄基异喹啉类生物碱。

Berbamine ( BER ) is a kind of bis-benzylisoquinoline alkaloids that was extracted from Chinese herb .

本文报道十二种四氢异喹啉类生物碱对大鼠脑内D-2,5-HT1和5-HT2受体的结合特性。

Investigation of some tetrahydroisoquinoline alkaloids on their in vitro affinities to D-2,5-HT_1 and 5-HT_2 receptors in rat brain was made using radioreceptor binding assay .

脂多糖、白介素-6和肿瘤坏死因子α与三氟吡啦嗪（TFP）或1-（5-异喹啉磺胺）-3-甲基哌嗪（H7）联合运用，则它们的刺激作用受到明显抑制。

While LPS , IL-6 and TNF α were combined with trifluoperazine or H 7 , their inductive effects were inhibited .

苄基异喹啉类化合物拮抗钙调素（CaM），对环核苷酸磷酸二酯酶（CaM-PDE）产生抑制作用。

Benzylisoquinoline compounds antagonized calmodulin ( CaM ) to inhibit the activity of CaM-dependent cyclic nucleotide phosphodiesterase ( CaM-PDE ) .

结果表明，在反应器的高效运转阶段，进水COD3500-4100mg.L-1，HRT24h，平均COD去除率达到96.51%，出水中有毒化合物苯、萘、菲、吡啶、喹啉、异喹啉等的浓度不可测出。

The results indicated that COD removal rate of 96.51 % was obtained and toxic compounds of benzene , naphthalene , phenanthrene , pyridine , quinoline , and isoquinoline were undetectable in the effluent .

小檗碱（Berberine，以下简称BBR）是一种异喹啉类生物碱，主要用于治疗胃肠炎、细菌性痢疾。

Berberine ( BBR ) is an isoquinoline alkaloid . It was mainly used for the treatment of gastroenteritis and bacillary dysentery .

目的：研究双苄基异喹啉化合物Ys96与阿霉素或长春新碱联合用药对体外培养人癌细胞系MCF7和KB的抗癌增效作用。

Objective : To study in vitro the anticancer interaction between Ys 96 , a bisbenzylisoquinoline compound derived from Stephania tetrandra , and adriamycin or vincristine against human cancer cell lines .

异喹啉盐可与不同结构的环烯醚及环烯醇醚进行Diels-Alder环加成反应，这是合成稠环化合物的有效途径。

Some isoquinolinium salts are able to react with a wide variety of cyclic enol ethers and cyclic vinyl ethers in Diels-Alder reaction , this is an effective way to form fused ring compounds .

借助于POLYGEN软件包在SGI－4D25G计算机上对四氢异喹啉钙拮抗剂CPU23，CPU80和硝苯啶的化学结构进行了分子模拟。

The chemical structures of CPU 23 and CPU 80 , two substituted tetrahydroisoquinoline calcium antagonists , and nifedipine were mimicked on a SGI-4D 25G computer with the POLYGEN software .

概括介绍了双苄基异喹啉类生物碱的两种基本类型berbamine系列和bebeerine系列（头接头与尾接尾；头接尾与尾接头）的~1H-NMR和~（13）C-NMR谱特征。

The review summarized the characteristics of ~ 1H-NMR and ~ ( 13 ) C-NMR spectra of two essential types of bisbenzylisoquinoline alkaloids ( BBI ), berbamine series and bebeerine series ( head to head and tail to tail ; head to tail and tail to head ) .

取代苄基异喹啉化合物与α-受体的亲和力及构效关系

Affinity to α - Adrenoceptor and QSAR of Some Substituted Benzylisoquinoline

抗心律失常药研究Ⅱ&1-对甲苯基-2-取代四氢异喹啉衍生物的合成

Studies on antiarrhythmic agents , ⅱ syntheses of 1-p-methylphenyl-2-substituted tetrahydroisoquinoline derivatives

1-（4-酰氧基苄基）四氢异喹啉类化合物的合成

Synthesis of 1 ( 4 Acyloxy Benzyl ) 1,2,3,4 Tetrahydroisoquinoline Compounds

水溶液中异喹啉与羟基的作用机理

The Reaction Mechanism Studies on Isoquinoline with Hydroxyl Radical in Aqueous Solution

某些异喹啉类生物碱对大鼠脑内单胺的影响

Effect of some isoquinoline alkaloids on monoamines in rat brain

千金藤碱等异喹啉类生物碱对5&羟色胺受体的阻断作用

5-HT receptor blockade properties of stephanine and other tetrahydroquinoline alkaloids

异喹啉类生物碱的生物活性和构效关系研究进展

Advances in studies on biological activity and structure-activity relationships of isoquinoline alkaloids

异喹啉类心血管药物研究进展再论现代汉语动结式的句法核心

Development of Cardiovascular Drugs Based on Isoquinoline Compounds from Chinese Medicinal Materials

新型四氢异喹啉类化合物的合成及其抗真菌和抗生育活性研究

Synthesis of novel tetrahydroisoquinolines and study of their anti-fungal and contraceptive activities

异喹啉及其衍生物在银电极上吸附行为的研究

Adsorption Behaviors of Isoquinoline and its Derivates on Ag Electrode