嗜铬细胞

刺激-分泌偶联离体嗜铬细胞模型的研究

Study in Isolated Chromaffin Cell Model of Stimulus-Secretion Coupling

人体嗜铬细胞培养的实验研究

Experimental study of culture of human chromaffin cell

与肾上腺髓质嗜铬细胞瘤相比较，异位嗜铬细胞中恶性肿瘤者较多。CT诊断正确率为87%。

The incidence of malignant ectopic pheochromocytoma was rather high reaching 13 % and the accuracy of CT diagnosis was 87 % in this series .

结论PKA在大鼠肾上腺髓质嗜铬细胞CA分泌过程中的作用不明显。

Conclusion PKA has no significant effect on CA secretion in rat adrenal chromaffin cells .

神经生长因子（NGF）可促进嗜铬细胞贴壁，存活和生长出神经轴突样突起，但是成人及成年大鼠肾上腺嗜铬细胞对于NGF的依赖程度存在种属差异。

NGF could enhance the attachment , Survival and neurite outgrowth , however , there appeared species differences .

方法应用胶原酶消化法分离、提取牛嗜铬细胞，进行APA微囊化；

Methods The bovine chromaffin cell ( BCC ) was isolated with collagenase ingestion .

APA微囊牛肾上腺嗜铬细胞移植治疗晚期癌痛研究

An Effective Evaluation of Transplantation of Microencapsulated Bovine Chromaffin Cells on Analgesia to Advanced Cancer Pain

APA微囊包裹对牛肾上腺嗜铬细胞分泌儿茶酚胺和亮氨酸脑啡肽的影响

The Affection of APA Microcapsulation on Catecholamine and Leucine-enkephalin Secretion from the Bovine Adrenal Medullary Chromaffin Cells

目的探讨作为5-羟色胺（5-HT）重要来源的肠嗜铬细胞（EC细胞）在功能性消化不良（FD）患者胃黏膜中的改变。

Objective To investigate the alteration of serotonin-producing gastric enterochromaffin ( EC ) cell in patients with functional dyspepsia ( FD ) .

NGF组肾上腺髓质嗜铬细胞膜可见杵状和绒毛状突起。

There were some drumstick-like and villiform processes in the adrenaline medullary chromaffin cells ( AMCC ) membrane of the NGF group .

肠易激综合征患者分泌5-羟色胺的肠嗜铬细胞的实验研究已发现肠易激综合征患者肠道黏膜中分泌5-HT的肠嗜铬细胞（EC细胞）和肥大细胞有所改变。

Several studies reported that there were alterations of enterochromaffin cells and mast cells in the intest-inal mucosa of patients with irritable bowel syndrome .

囊化牛肾上腺嗜铬细胞移植48个月时移植区D2受体活性较对侧明显提高。

The activity of D2 receptor in microencapsulated BCCs at48 months of post-transplantation was higher than that in the opposite side .

通过牛嗜铬细胞在添加壳聚糖的培养液中培养、牛嗜铬细胞的ACA微囊化培养以及ACA微囊化牛嗜铬细胞的动物移植实验来考察微胶囊材料的生物相容性。

Primary bovine chromaffin cell was cultured in the presence of chitosan in order to test the in vitro biocompatibility of chitosan .

结果显示：大鼠和猫的嗜铬细胞内NSE与胺共存于嗜铬颗粒内。

It was shown that NSE was exclusively localized within the chromaffin granules of all the adrenal chromaffin cells in rats and cats .

羊蛛网膜下植入APA微囊化牛嗜铬细胞脑脊液亮氨酸脑啡肽和儿茶酚胺含量的变化

Concentration change of catecholamine and leucine-enkephalin in sheep cerebrospinal fluid after APA microencapsulated bovine chromaffin cells transplantation to the spinal subarachnoid space

目的研究糖皮质激素（GC）对大鼠肾上腺髓质嗜铬细胞（AMCC）分泌儿茶酚胺（CA）的作用机制。

Objective To study the effects of glucocorticoids ( GC ) on stimulus-catecholamine ( CA ) secretion coupling in rat adrenal chromaffin cells ( AMCC ) .

大鼠嗜铬细胞分泌的膜片钳和fura-2联合检测

The Detecting of Secretion of the Rat Adrenal Chromaffin Cells by Combing Fura 2 with Patch Clamp Measurements

目的：探讨微囊牛肾上腺嗜铬细胞（BCC）移植治疗晚期癌痛的有效性。

Objective : To evaluate the effect of transplantation of microencapsulated bovine chromaffin cells ( BCC ) on pain stopping for the patients with advanced malignant tumors .

通过检测肠嗜铬细胞数量及测定血清5-HT、NO含量变化，阐明芳香化湿方药对应激状态下胃肠动力的影响。

Through the determination of cell and the secretion of intestinal 5-HT and serum NO variation in content of wet aroma , improve the condition of stress formulas gastrointestinal influence . 3 .

目的：观察接受牛嗜铬细胞（BCC）移植的大鼠脑脊液中儿茶酚胺及脑啡肽含量的变化。

Aim : To detect the concentration of the leucine enkephalin and catecholamine in rat cerebral spinal fluid ( CSF ) after bovine chromaffin cell ( BCC ) implantation .

目的：探讨微囊化牛嗜铬细胞（BCC）蛛网膜下腔移植对疼痛大鼠脊髓后角神经元活动的影响。

Aim : To observe the effect of transplantation of microencapsulated bovine chromaffin cells ( BCCs ) on activity of nerve cells in spinal dorsal cord of formalin-induced rats .

目的观察微囊化牛嗜铬细胞（BCC）大鼠脑内移植的效果及微囊的作用。

Objective To observe the immune separation effects of micro capsules from alginate polylysine alginate ( APA ) in the rat cerebral transplantation of bovine chromaffin cell ( BCC ) grafts .

结果肾上腺皮质腺瘤、皮质腺癌、嗜铬细胞瘤和嗜铬细胞癌的皮质中均可见CgA染色阳性细胞，皮质增生、髓质增生和正常肾上腺病例皮质CgA染色阴性；

Results The expression of CgA was detected in cortex of adrenocortical adenoma , adrenal neoplasm and chromophile tumor , but not in that of hyperplasia and normal adrenal .

结论微囊化牛嗜铬细胞移植对福尔马林致痛大鼠有镇痛作用，可以提高脑脊液中儿茶酚胺的含量，可以抑制福尔马林致痛大鼠脊髓后角c-fos基因的表达。

Conclusion Transplant of microencapsulated bovine chromaffin cells can produce analgesic effect on formalin-induced Rats , and increase the concentrations of the catecholamine in CSF , and reduce the expression of c-fos gene in spinal dorsal cord of formalin-induced rats .

目的观察海藻酸钠-聚赖氨酸-海藻酸钠（APA）微囊化牛肾上腺嗜铬细胞（BCC）异种移植对慢性顽固性疼痛患者的镇痛效应、作用持续时间及毒副作用。

Objective To study the analgesic effect , the effective duration and the toxic and side effects of Alginate Polylysine Alginate ( APA ) microencapsulated bovine chromaffin cells ( BCC ) xenotransplantation on the terminal pain of 20 patients .

方法：分别将APA空微囊、牛嗜铬细胞（BCCs）和APA微囊化BCCs（APABCCs）移植到绵羊的蛛网膜下腔中，观察宿主细胞免疫指标和组织形态学的变化。

Methods : To observe changes of cellular immune and tectology of sheeps after hollow microcapsules , Bovine Chromaffin Cells ( BCCs ) and APA Microencapsulated BCCs ( APA-BCCs ) transplanted to the spinal subarachnoid space .

目的：了解海藻酸钠-多聚赖氨酸-海藻酸钠微囊化牛肾上腺嗜铬细胞（APA-BCC微胶囊）植入癌痛患者脊髓蛛网膜下产生镇痛的同时对脑脊液中内源性阿片肽类物质含量的影响。

AIM : To study the effect of APA BCC ( alginate polylysine alginate microencapsulated bovine adrenal medullary chromaffin cells ) microcapsule transplantation into the subarachnoid space of cancer pain patients on endogenetic enkephalin concentration in cerebrospinal fluid ( CSF ) when analgetic effects occurs .

大鼠肾上腺嗜铬细胞原代培养的一种实用方法

A Practical Method for Primary Culture of Rat Adrenal Chromaffin Cells

嗜铬细胞分泌的模型研究

A Kinetic Model of Control on Secretion in Chromaffin Cells

帕金森病样大鼠牛嗜铬细胞脑内移植后的行为和组织学观察

The behavioral and morphological observation following transplantation of bovine chromaffin