同源二聚体

通过胞内免疫荧光实验观察，我们发现这个核酸结合区域对NACA同源二聚体在细胞核内的定位有关键作用。

Through the immunofluorescence assay in vivo , we discovered that this nucleic acid-binding region is crucial for the location of the NACA homodimer in the nucleus .

另外我们发现Siah-1S不仅可以和Siah-1结合形成异源二聚体，也可以和自身形成同源二聚体。

Additionally , Siah-1S is found to interact with Siah-1 to form heterodimer or with itself to form homodimer .

EPO刺激后1分钟，EPOR形成同源二聚体，出现酪氨酸磷酸化；

Dimerization and tyrosine phosphorylation of EPOR were found after 1 minute incubated with EPO .

同时，MDH多为同源二聚体或四聚体结构，也可以作为研究寡聚蛋白结构和功能的理想模型蛋白质。

For its homo-dimer or tetrad structure , MDH is regarded as an ideal model for research on oligomeric protein structure and function .

在凋亡相关基因中Bcl-2家族研究的较为深入，Bcl-2基因是主要的抑凋亡基因，Bax是Bcl-2的同源二聚体，能对抗Bcl-2对细胞凋亡的抑制作用。

Bcl - 2 family is a well studied gene related to apoptosis in which Bcl - 2 gene can prevent cells from apoptosis . Bax is homologous to Bcl - 2 and prompt cell apoptosis .

NAC蛋白通过形成同源二聚体和异源二聚体来决定行使蛋白伴侣或转录共激活子的功能，从而在细胞翻译过程和转录过程之间建立了联系。

NAC proteins form homo-and heterodimers to decide their functions as protein chaperone or transcription coactivator , and make a connection between translation and transcription processes in cell .

米非司酮使Bcl-2/Bax凋亡调控途径平衡失调而诱发流产：Bax增多可导致Bcl-2/Bax的平衡关系被打破，形成Bax同源二聚体增多，最终诱发Bax介导的细胞凋亡，从而引起流产结局。

Mifepristone evoke abortion pass dysequilibrium of Bcl-2 / Bax apoptosis control pathway : the increasing of Bax induce dysequilibrium of Bcl-2 / Bax and Accumulation of Bax / Bax , at last it evoke cell apoptosis .

戊型肝炎病毒衣壳蛋白同源二聚体的相互作用结构域

Interface Domain of Hepatitis E Virus Capsid Protein Homodimer

本文用支持向量机方法从蛋白质一级结构出发区分同源二聚体、同源三聚体、同源四聚体和同源六聚体。

Support vector machine approach is applied to classifying the homodimers , homotrimers , homotetramers and homohexamers from the primary structure .

另一方面，纯化的同工酶4在pH11时有突显的酶活高峰，且其分子构型为同源二聚体，这是该酶区别于其它单功能过氧化氢酶的独特之处。

On the other hand , the new purified enzyme displayed the unique properties of a sharp maximum activity at pH 11 and an uncommon structure of homodimer , which are both distinct from the common characteristics of the monofunctional catalase .

EGFR同相应的配体结合形成同源或异源二聚体，从而激活细胞内下游信号传导通路。

Upon binding to corresponding ligands . the EGFR forms homo-or heterodimers and activate downstream signal transduction pathways .

EGF受体家族成员通过配体形成同源或异源二聚体，活化胞内酪氨酸激酶，从而激活信号转导通路。

EGFR family members binding with ligands to form homo-dimers or hetero-dimers activate intracellular tyrosine kinase , which further activate cysto-signal transduction pathway .