卡铂

紫杉醇联合卡铂新辅助化疗Ⅱb期宫颈癌50例

Neoadjuvant Chemotherapy with Paclitaxel and Carboplatin for 50 Cases with Cervical Cancer Stage ⅱ b

环磷酰胺/卡铂联合化疗对卵巢癌患者外周血单个核细胞DNA损害

DNA damage in peripheral mononuclear blood cells of ovarian cancer patients during combining chemotherapy with cyclophosphamide / carboplatin

其次为卡铂与细胞因子同时组（P＜0.01）；

The highest transformation of spleen T cell was in the simultaneous group ( P < 0 . 001 ) .

卡铂和5－Fu联合化疗晚期鼻咽癌48例疗效分析

Combined chemotherapy with carboplatin and 5 - fluorouracil in the

卡铂、5－Fu序贯腔内用药治疗癌性腹水

Intraperitoneal Carboplatin and 5-Fu in Sequence in the Treatment of Malignant Ascites

置管引流后卡铂腹腔灌注化疗联合EP方案治疗妇科恶性腹水48例疗效分析

A Curative Analysis of 48 Cases with Gynecological Malignant Ascites

卡铂复合液诱导胃癌细胞凋亡和p53蛋白表达的研究

Study on Apoptosis and p53 Protein Expression Induced by Carboplatin Mixture Liquid in Gastric Cancer Cell Line

采用HPLC研究了卡铂对光和热的稳定性。

The stability of carboplatin ( 1 ) and its aqueous solution under light and heat was studied by HPLC .

5FU8小时静滴联合CF、卡铂治疗晚期鼻咽癌的临床研究

Clinical trial of 5FU / CF and carboplatin combination chemotherapy in patients with advanced

卡铂复合液对大鼠腹腔内化疗后腹膜Ⅰ型和Ⅲ型胶原mRNA表达的影响

Effect of Carboplatin Mixture Liquid on the Expression of Type I and type ⅲ Collagen mRNA Levels of the Peritoneum After Intraperitoneal Chemotherapy

流式细胞仪检测结果发现EPA联合卡铂组的凋亡率较单用卡铂组明显增加。

Flow cytometry results showed that the apoptosis rate of combination group than carboplatin group significantly increased .

目的研究国产卡铂（CBP）的临床药代动力学与药效学。

Objective : To study the clinical pharmacokinetics and pharmacodynamics of carboplatin .

而内毛细胞的缺失是发生在注射卡铂后72h。

However , The reduction of the inner hair cells occurred within 72 hours .

口腔鳞癌对卡铂联合5-Fu新辅助化疗方案敏感性的预测研究

Prediction of chemosensitivity to combination neoadjuvant chemotherapy with carboplatin and 5-Fu for the patients with oral squamous cell carcinoma

卡铂多相脂质体腹腔注射对615小鼠U（14）移植瘤腹膜后淋巴结和肺转移的抑制作用

Intraperitoneal administration of carboplatin encapsulated in polyphase liposome suppressed the metastasis of tumor cell ( U14 ) to the retroperitoneal lymphnodes and the lung of 615 mice

CE组：卡铂300mg/m2，静脉滴注，第1天，足叶乙甙100mg/d，静脉滴注，第1~5天。

Carboplatin 300 mg / m2 on day 1 and etoposide 100 mg / d on days 1 to 5 were given to patients in CE group .

术后给予以铂类为主的联合化疗，其中13例行紫杉醇+顺铂或卡铂（TP）方案化疗，9例行顺铂+阿霉素+环磷酰胺（PAC）方案化疗。

Thirteen cases received paclitaxel + cisplatin ( TP ) and 9 received cisplatin + doxorubicin + cyclophosphamide ( PAC ) combination chemotherapy .

结论：卡铂、顺铂联合，经不同途径给药，由于抗肿瘤作用相加，而毒性作用分担，治疗有胸水的Ⅲb～Ⅳ期非小细胞肺癌疗效好，副反应小，可安全用于临床。

Conclusion : The combined chemotherapy Carboplatin and Cisplatin in different way to add more Anti-neoplasm effects of the two drugs and reduce the toxicity of treatment of stage ⅲ b ~ⅳ non-small cell lung cancer with pleural effusion .

结论利用卡铂联合5-Fu作为化疗方案的时辰化疗联合动脉化疗治疗口腔颌面部鳞癌可提高疗效，减少毒副作用，值得临床推广。

Conclusion Arterial chrono-chemotherapy of CBP and 5-FU for the patients with OSCC can increase therapeutic effects and reduce toxicities comparing with routine chemotherapy .

紫杉醇加卡铂是晚期EOC的标准一线化疗方案。

At present , paclitaxel plus carboplatin become the first-line chemotherapeutic regimen of advanced EOC .

单药拓朴替康与CE方案（足叶乙甙+卡铂）的反应率相似[OR0.59,95%CI（0.22,1.60）]；

The response rate of monotherapy with topotecan was similar with that of CE ( carboplatin + etoposide ) regimen with OR 0.59 and 95 % CI 0.22 to 1.60 ;

卡铂、阿霉素微囊对Tca8113作用的体外实验观察

The experimental observation on effect of carboplatin ADM microcapsules for TCA 8113

同时银杏叶多糖与环磷酰胺、卡铂、顺铂、5-Fu、盐酸阿霉素等药物合用，其抑制鼻咽癌细胞、宫颈癌细胞的生长能力强于各药物单独使用的抑制率。

The inhibition ability of CTX , carboplatin cisplatin , doxorubicin , 5-fluorouracil combined with Ginkgo biloba polysaccharide were higher than these drug used alone .

结论卡铂联合5FU作为宫颈癌NACT方案是有效、可行、安全的。

Conclusion NACT based on carboplatin is effective , feasible and safe .

结论胸腔内置入中心静脉导管化疗达到CR的例数提高，可明显降低卡铂与α-2b干扰素联合治疗次数，副作用小。

Conclusions Intrapleural chemotherapy by center vein catheter may increase CR and decrease application times of Carboplatin and α - 2b Interferon in the treatment of malignant pleural effusion , with fewer side effects .

结果：注射卡铂后从24h～3个月，灰鼠的外毛细胞基本无缺损。

Result : Loss of outer hair cells was not observed on basal membrane from 24 hours to 3 months after drug administration except one ear .

目的为了观察正常灰鼠和卡铂（Carboplatin）耳中毒灰鼠耳蜗单个疆孔（habenulaperforata）内的神经纤维数量。

Objective To examine the number of nerve fibers in the habenula perforata of the cochlea in normal and carboplatin treated chinchillas .

卡铂缓释微球瘤内注射治疗兔肝VX2肿瘤最适剂量研究

Study on optimal dosage of slow released carboplatin microspheres for intratumoral injection on rabbit VX_2 liver tumor

观察免疫细胞化学染色的结果，可以发现联合组抗凋亡因子bcl-2的表达较对照组、EPA组和卡铂组明显减弱。

The expression of anti-apoptotic factor bcl-2 of combined group was significantly reduced than the control group , EPA group and carboplatin group by observing the results of immunocytochemical staining .

方法：用单次剂量的卡铂（50mg/kg）静推造成Hb较长时间的降低。

Methods : Anemia was induced using a single dose of carboplatin ( 50mg / kg , iv ) resulting in a long lasting reduction of the hemoglobin concentration .