冠心苏合丸

[方法]采用内标法，选用OV-1弹性石英毛细管柱，建立了冠心苏合丸中冰片和苯甲酸苄酯含量的气相色谱测定方法。

A gas chromatographic method using a fused silica capillary column OV-1 and internal standard was established .

冠心苏合丸抗胃溃疡作用机理初探

Exploration of anti-stomach ulcer role of Guan Xin Su He pills

冠心苏合丸系列组方对犬心肌梗死影响的比较药理学研究

Study on therapeutic effects of series of Muskone on myocardial infarction canines

冠心苏合丸相关的肾小管间质肾病及其临床病理特点

An analysis of the clinical and pathological characteristics of Guan Xin Su He Wan associated tubulointerstitial nephropathy

方法将患者48例（辨证为寒凝血瘀证）随机分为治疗组与对照组，分别口服心泰康颗粒和冠心苏合丸，连用4周；

Methods : 48 patients were randomly and blindly assigned to the treatment group and the controlled group .

根据实验推测，改善胃粘膜血流量是冠心苏合丸抗溃疡作用的主要机理。

The experiment indicated : the principal mechanism of Guan Xin Su He Pills anti-stomach ulcer role was change the volume of flow of gastric mucosa .

对于中老年患者的肾损害，尤其是合并有冠心病中老年患者的肾损害应注意除外冠心苏合丸所致肾损害。

To diagnose renal injury of elder patients , especially accompanied with coronary heart disease , the renal injury induced by GW should be carefully distinguished .

结果：1.冠心苏合丸系列药材在小鼠急性毒性试验中未发现有急性死亡现象，且药物的最大给药量均超过临床剂量的几十倍甚至几百倍。

Acute toxicity test in mice was not found to have acute mortality , and the maximum tolerated dose of drugs were tens or hundreds of times more than the clinical dose . 2 .

因此，这三种药物是相对安全的，土木香和冠心苏合丸（含土木香）可以代替青木香和冠心苏合丸（含青木香）在临床上继续使用。

Therefore , these three drugs are relatively safe . Radix Inulae and Guanxin Suhe Wan ( with Radix Inulae ) can replace Aristolochia debilis and Guanxin Suhe Wan ( with aristolochia debilis ) to be used in clinical practice .