克拉霉素

B组28例给予奥美拉唑、克拉霉素和甲硝唑治疗。

28 cases in group B were given omeprazole , clarithromycin , and metronidazole .

克拉霉素10～15mg/（kg·d），每日2次。

And clarithromycin ( 10-15 mg / kg / d , bid ) .

HPLC内标法测定克拉霉素含量

Determination of Clarithromycin With HPLC Internal Standard Method

方法92例HP阳性的十二指肠溃疡患者随机分为3组，A组为治疗1组31例，口服奥美拉唑+克拉霉素+大蒜素胶囊治疗；

Methods 92 patients with HP-positive duodenal ulcer were randomized allocated to three groups .

HPLC测定克拉霉素及其制剂的含量

Determination of Clarithromycin by HPLC

阿克拉霉素联合阿糖胞苷对survivin基因表达的原代急性白血病细胞增殖的影响

Sensitivity of survivin-positive primary acute leukemia cells to aclacinomycin and cytarabine

克拉霉素治疗小鼠Lewis肺癌的实验研究

Therapeutic effect of Clarithromycin on Lewis lung carcinoma in mice

TGA测定克拉霉素热分解动力学参数

Determination of clarithromycin thermal decomposition kinetic parameters with thermogravimetry analysis

结果1994～1998年氨基糖苷类、硫霉素、多粘菌素B、克拉霉素、麦迪霉素均无耐药菌；

RESULTS All of campylobacters were isolated from 1994 to 1998 . No strain was resistant to aminoglycosides , imipenem , polymycin B , clarithromycin , josamycin , midecamycin .

测定克拉霉素、氧氟沙星的MIC值；

The MICs of clarithromycin and ofloxacin were measured ;

目的：探讨克拉霉素（CAM）对急性肺损伤（ALI）的预防作用及其作用机理。

Objective : To study preventive effect of clarithromycin ( CAM ) on acute lung injury ( ALI ) induced by oleic acid .

目的建立萃取-薄层色谱法（TLC）检查克拉霉素注射液中的有关物质及分解产物。

Objective The extraction - TLC method for the detection of the related substances in clarithromycin injection was established .

目的：观察国产克拉霉素的短程三联疗法根除幽门螺杆菌（Hp）感染的疗效及不良反应。

AIM : To determine efficacy and adverse reactions of domestic clarithromycin combined shortterm triple therapy for eradication of Helicobacter pylori ( Hp ) .

克拉霉素血药浓度HPLC-MS测定方法的改进及药代动力学研究

Modified HPLC-MS method in determination of plasma concentration of clarithromycin and its pharmacokinetic study

克拉霉素组18例Hp根除患儿，30个月内随访复发率5.6%（1/18）。

The recurrence rate of 18 Hp eradicated children treated with CLA triple therapy was 5.6 % ( 1 / 18 ) during the 30 months follow-up .

阿糖胞苷、阿克拉霉素联合G-CSF治疗50例复发急性髓系白血病的临床研究

Low-dose Cytarabine and Aclarubicin in Combination with Granulocyte Colony-Stimulating Factor Priming in 50 Patients with Relapsed Acute Myeloid Leukemia

克拉霉素抑制b-FGF诱导血管生成的实验研究

Study on anti-angiogenesis effect of clarithromycin on angiogenesis induced by b-FGF

耐药情况：65%（E-test法）对甲硝唑耐药，37.5%对阿莫西林耐药，克拉霉素耐药率为0。

37.5 % to AM ; the drug resistant rate of CH was zero .

采用Lewis肺癌C57BL/6小鼠模型，观察比较克拉霉素对肿瘤组织内微血管密度、移植瘤体积、肺脏转移和实验小鼠存活时间的影响。

The quantitation of microvessel density in tumor , occurrence of lung metastasis , tumor volume and mean survival time were analyzed in Lewis tumor bearing C57BL / 6mice .

目的：观察雷尼替丁加克拉霉素、阿莫西林治疗幽门螺旋菌（HelicobacterPylori，HP）感染相关的十二指肠溃疡（DU）及降低复发率的效果。

Objectives : To evaluate the curative effect and the recurrence rate of duodenal ulcer ( DU ) with helicobacter pylori ( HP ) infection with ranitidine , kromycin and amoxycillin .

寡核苷酸微阵列技术用于检测幽门螺杆菌克拉霉素耐药相关23SRRNA基因多态性

Screening of single nucleotide polymorphism of a 23S rRNA gene from Helicobacter pylori associated with clarithromycin resistance using oligonucleotide microarray

目的研究二妙龙胆合剂的药理及与克拉霉素联合应用治疗非淋菌性尿道炎（黏液脓性宫颈炎）[NGU（MPC）]的临床疗效。

Objectives To study the pharmacologic mechanism of Ermiao-radix-gentianae mixture ( ERM ) and its therapeutic effects associated with clarithromycin in the treatment of nongonococcal urethritis ( mucopurulent cervicitis ) .

目的：探讨克拉霉素和氟罗沙星对铜绿假单胞菌（PA）生物被膜的影响。方法：选取临床分离的呼吸道PA7株，用平板法培养细菌生物被膜，银染色法鉴定；

OBJECTIVE : To observe the effects of clarithromycin and fleroxacin on Pseudomonas aeruginosa ( PA ) biofilm METHODS : Clinical isolates of 7 strains of PA from respiratory tract were cultured with modified plate culture method ;

方法：通过正交试验设计，以Td值为指标，优选出克拉霉素胶囊的最佳处方组成为每粒含克拉霉素0.25克，微晶纤维素0.075克，优质羧甲基淀粉钠0.015克。

Method : By orthogonal design with Td as index , the optimal formula of clarithromycin capsules was 0.25 g clarithromycin , 0.075 g microcrystalline cellulose and 0.015 g DST in every capsule .

目的评价预激方案（低剂量阿糖胞苷加阿克拉霉素或高三尖杉酯碱联合粒细胞集落刺激因子）治疗难治和继发性急性髓系白血病（AML）的疗效。

Objective To evaluate the efficacy of the priming regimen ( low-dose cytarabine and aclarubicin or homoharringtonine in combination with granulocyte colony-stimulating factor ) on refractory and secondary acute myeloid leukemia ( AML ) .

方法对二妙龙胆合剂进行体外抗菌试验和毒理试验，并进行联用治疗NGU（MPC）与单用克拉霉素的疗效观察和对比。

Methods ERM 's anti-bacteria and toxicological test were performed in vitro , and the therapeutic effects of ERM plus clarithromycin versus clarithromycin alone in NGU ( MPC ) treatment were also observed .

观察阿克拉霉素（Acla）与阿糖胞苷（Ara-c）联合方案（AA方案）治疗难治及复发性急性白血病的疗效，对22例难治及复发性急性白血病患者进行了AA方案化疗。

To observe the effect of Acla and Ara c ( AA plan ) on acute refractory and recurrent leukemia . 20 patients with acute refractory and recurrent leukemia were treated with AA plan .

方法采用琼脂稀释法和E-test药敏试验检测幽门螺杆菌对甲硝唑、阿莫西林和克拉霉素的药敏和耐药性。

METHODS The susceptibility of HP to metronidazole ( MZ ), amoxicillin ( AM ) and clarithromycin ( CH ) were tested by E test and agar diluted method .

结论：1.克拉霉素、多潘立酮、莫沙必利和伊托必利均能够提高SD大鼠胃和十二指肠肌电活动的振幅及频率，其中伊托必利作用最强，其次是莫沙必利和多潘立酮，克拉霉素最弱。

Itopride , mosapride , domperidone , and clarithromycin can increase the amplitude and frequency of stomach and duodenum on the SD rats , and among the total , itopride have the best power , second are mosapride and domperidone , and the least is clarithromycin . 2 .

目的：比较宫颈癌HeLa细胞对阿克拉霉素低密度脂蛋白复合物（ACMLDL）及游离ACM的摄取量及ACMLDL对HeLa细胞DNA及RNA合成的抑制作用。

Objective : To study cellular intake of aclacinomycin LDL ( ACM LDL ) complex and free ACM by HeLa cells of uterine carcinoma . Inhibition effect of this complex on the synthesis of DNA and RNA of the cancer cells was also studied .