亚低温治疗

结论：亚低温治疗可以降低急性脑卒中患者血清IL-2、IL-6的水平，抑制卒中后炎症反应，保护脑神经细胞。

Conclusions : Mild hypothermia treatment can decrease the serum levels of IL-2 and IL-6 in patients with acute stroke and inhibit the inflammatory response so that the cerebral cells can be protected .

结论通过亚低温治疗能抑制NSE的释放，对重型颅脑损伤病人的神经元细胞和神经内分泌细胞继发性损害有保护性作用，在临床上值得推广应用。

Conclusion Mild hypothermia treatment can dramatically inhibit the release of NSE , it can protect the neuron and neurosecretory cell that they haven 't been destroyed continuously , so it was worth using greatly in the clinical treatment .

亚低温治疗重型颅脑外伤后血SOD含量的变化

Changes of blood SOD levels in patients with severe brain injury after treatment with moderate hypothermia

重型脑伤患者亚低温治疗后脑组织氧分压、二氧化碳分压和pH值的变化

Changes of brain tissue oxygen tension , carbon dioxide tension and pH value after mild hypothermia treatment in patients with severe brain injury

亚低温治疗新生儿缺氧缺血性脑病临床效果的Meta分析

Meta-analysis of clinical efficacy and safety of hypothermia for neonates with hypoxic ischemic encephalopathy

结论经亚低温治疗可以降低DAI后升高的血小板计数、纤维蛋白原定量及D-二聚体含量。

Conclusions : The platelet count , fibrinogen and D-dimer are decreased significantly by sub-hypothermia therapy .

亚低温治疗能有效缓解SHI后的脑组织缺氧及酸中毒，从而改善患者预后。

Mild hypothermia therapy may reduce the brain tissue hypoxia and acidosis , and improve the prog ˉ nosis .

[目的]探讨选择性脑亚低温治疗对脑卒中后抑郁（PSD）的影响。

Objective : To probe into influence of selective sub-hypothermia therapy on depression of apoplexy patients .

目的探讨亚低温治疗重度弥漫性轴索损伤（DAI）的疗效与机制。

Objective To analyze the effect and mechanism of hypothermia ( HT ) treatment for severe diffuse axonal injury .

目的：观察重型颅脑损伤（SHI）亚低温治疗过程中的脑氧代谢变化规律。

Objective : To study the changes of brain oxygen metabolism during mild hypothermia in patients with severe head injury ( SHI ) .

结果亚低温治疗前后及亚低温治疗组与对照组比较神经功能明显改善，体温、NO、ICAM-1及IL-1明显降低，SOD增加。

Results The neurologic function and SOD improved obviously ; NO , ICAM-1 , IL-1 and temperature decreased after moderate hypothermic therapy ;

结论颅脑局部亚低温治疗可显著降低急性脑梗死患者血清IL-8和ICAM-1浓度，减轻脑梗死后炎症反应，保护缺血脑组织。

Conclusion Local mild hypothermia therapy can obviously decrease the concentrations of serum IL-8 and ICAM-1 in patients with cerebral infarction .

亚低温治疗犬颅脑枪弹伤后局部脑组织c-jun蛋白的表达

Expression of c-jun protein in local cerebral tissue after mild hypothermia treatment of craniocerebral gunshot wounds in dogs

结论亚低温治疗能减少脑出血后脑组织钙的增加，减少钙平衡失调，显著减少实验性脑出血大鼠24h内病死率。

Conclusion Hypothermic therapy can reduce the mortality and the content of calcium in the brain after experimental cerebral hemorrhage in rats .

结论颅脑枪弹伤后全身亚低温治疗能够抑制脑神经元c-jun蛋白的表达。

Conclusion Overall mild hypothermia after craniocerebral gunshot wounds can restrain the expression of c-jun protein in brain neurons in dogs .

结论亚低温治疗能明显降低重型颅脑损伤患者ICP，改善脑组织氧代谢。降低患者死亡率及致残率。

Conclusions The therapy of moderate hypothermia in severe head injury can obviously descend ICP , reform brain tissue oxygen metabolism , lower death rate and disablement rate .

结论1急性脑梗死病人血清S-100b蛋白水平明显高于正常人，因此S-100b蛋白可作为脑梗死病情观察指标。2局部亚低温治疗能降低脑梗死病人血清S-100b蛋白水平，提示局部亚低温能发挥脑保护作用。

Conclusion local mild hypothermia therapy can decrease the levels of serum S-100b protein in cerebral infarction patients .

方法36例SHI患者，随机分为常规治疗对照组和常规治疗+亚低温治疗组，各18例。

Methods Thirty-six patients with SHI were randomly divided into conventional therapy group ( control group ) and mild hypothermia therapeutic group ( therapeutic group ), with 18 patients in each group .

在将机电一体化技术应用于传统制冷的基础上，研制了颅脑亚低温治疗仪。该治疗仪主要包括制冷系统、LCD显示系统、数据采集系统及智能变频控制系统。

A hypothermia instrument consisting of refrigerating apparatus , LCD display device , data collection system and intelligent frequency control system is developed on the basis of applying of the modern mechatronics to the conventional refrigeration .

目的：研究颅脑枪弹伤常温下及全身亚低温治疗后脑神经元c-fos蛋白表达的变化。

AIM : To investigate the changes in the expression of c fos protein in cerebral cortex of canines with craniocerebral gunshot wounds after treatment with normothermia and with mild hypothermia respectively .

结果亚低温治疗24h后ICP逐渐下降，脑组织PO2逐渐上升，与对照组比较差异有显著性（P<0.05）。

Results In moderate hypothermia group the ICP gradually decreased and PO2 increased after 24 hours of hypothermia , with obvious difference from the control group ( P < 0.05 ) .

直接脑温监测与直肠温度监测在sTBI亚低温治疗中的应用分析

Clinical exploration of direct cerebral temperature monitoring and rectal temperature monitoring in mild hypothermia therapy of severe cerebral injury

结果：常温及亚低温治疗4～10天后两组病人的GCS评分对比及治疗6个月时的GOS评分比较，均有明显统计学差异，亚低温治疗组的疗效及预后明显优于对照组（P0.05）。

Results : GCS after mild hypothermia treatment in 6 ~ 10 days and GOS at 6 months after injury were higher than that in control group , there were significant differences ( P0.05 ) .

方法：观察大鼠脑损伤亚低温治疗后凝血酶原时间（PT）、部分凝血活酶时间（APTT）、凝血酶时间（TT）和纤维蛋白原（FIB）的变化。

METHODS : Prothrombin time ( PT ), activated partial thromboplastin time ( APTT ), thrombin time ( TT ) and fibrinogen ( FIB ) levels were studied in cerebral injured rats after treatment with mild hypothermia .

目的了解神经源性肺水肿（NPE）患者应激激素的变化，并进一步探讨亚低温治疗NPE的临床意义。

Objective to investigate the changes in stress hormones in neurogenic pulmonary edema ( NPE ) and explore the clinical value of mild hypothermia therapy for treatment of NPE .

[目的]研究亚低温治疗对重型颅脑创伤患者脑脊液中TNFα、IL-6及IL-8水平的影响，并探讨亚低温治疗的机理。

[ Objective ] In order to research on the effection of moderate hypothermia on cerebrospinal fluid tumor necrosis factor a ( TNFa ), interleukin-6 ( IL-6 ) and interleukin-8 ( IL-8 ) levels and therapy mechanism after severe traumatic brain injury in humans .

目的探讨亚低温治疗对重型颅脑损伤患者血清中肿瘤坏死因子-α（TNF-α）、白细胞介素（IL）-1β、IL-6、IL-8的影响及临床意义。

Objective To explore the effect of mild hypothermia on tumor necrosis factor alpha ( TNF - α), interleukin-1 β( IL-1 β), interleukin-6 ( IL-6 ) and interleukin-8 ( IL-8 ) in serum of patients with severe traumatic brain injury and its clinical significance .

目的研究急性重型颅脑创伤（sTBI）病人脑脊液（CSF）中白细胞介素-6（IL-6）含量的变化及亚低温治疗对其影响与临床意义。

Objectives To investigate changes of Interleukin-6 ( IL-6 ) concentration of cerebrospinal fluid ( CSF ) in patients with acute severe traumatic brain injury ( sTBI ), the effect of moderate hypothermic therapy on IL-6 and clinical significance .

目的：探讨亚低温治疗外伤性急性弥漫性脑肿胀（PADBS）的机理与疗效。

Objective : To study the therapeutic mechanism and effect of mild hypothermia on the patients with posttraumatic acute diffuse brain swelling ( PADBS ) .

目的对重型颅脑损伤患者在亚低温治疗过程中的脑脊液PO2、PCO2、pH值、乳酸水平及动脉血pH值进行监测分析，探讨亚低温治疗对重型颅脑损伤脑脊液酸碱平衡的影响。

Objective To investigate the effects of mild hypothermia on brain acid base balance after severe head injury through monitoring the changes of CSF PO 2 , PCO 2 , pH and lactate level and arterial pH in patients with severe head injury treated with mild hypothermia .