五味子乙素

五味子乙素干预二氧化硅致大鼠肺损伤的研究

Research on Effects of Schisandrin B Against Silica-induced Lung Injury in Rats

人工经验判别、水浸率、五味子乙素三者均能建立近红外光谱数据分析模型。

The experience method , lixiviation percent of water and the content of schisandrin B could be built data analysis model of NIRS .

五味子乙素对小鼠肝细胞微粒体细胞色素P-450的诱导作用

Induction of hepatocyte microsomal cytochrome P-450 by schizandrin B in mice

此外，五味子乙素能显著促进~（14）C-苯丙氨酸掺入肝脏蛋白质，并使肝细胞微粒体细胞色素P-450及蛋白质含量显著增加。

In addition , Schizandrin B Was found to enhance-the incorporation of ~ ( 14 ) G-phenylalanine into liver protein , and to increase hepatic microsomal cytochrome P-450 and protein contents significantly .

五灵胶囊中五味子乙素在小鼠体内药代动力学研究

Pharmacokinetic Study of Schizandrin in Wuling Capsules in Mice

回归正交试验设计优化五味子乙素的提取工艺

Optimization of Extract Processing of Schizandrin in Schisandra Chinensis by Orthogonal Regression Design

体外释放实验表明具有较好的缓释作用，为五味子乙素提供一个具有靶向及缓释作用的新剂型。

In vitro release experiments show that it has a better effect of schisandrin B , to provide a targeted and sustained release of new dosage forms .

五味子乙素系从中药五味子分离出的成分之一，有抗肝损伤和解毒作用，同时亦引起小鼠肝脏重量增大。

Schizandrin B , one of the components isolated from Fructus Schizandrae , was found to have protective action on liver injury and to increase the weight of liver in mice .

以上结果表明，五味子乙素对药酶有诱导作用，其引起的肝脏增大主要系肝实质细胞体积增大，同时伴有肝细胞增生。

From these results , it may be concluded that Schizandrin B is'an inducing agent of drug metabolizing enzyme , and the enlargement of the liver caused by Schizandrin B is mainly , due to hypertrophy and to a lesser degree , hyperplasia .

方法采用回归正交试验设计，通过HPLC测定五味子中五味子乙素的含量，确定最佳提取工艺。

Methods Orthogonal regression design was used in experience . The content of Schizandrin in Schisandra Chinensis was determinated by HPLC .

结果五味子中五味子乙素提取的最佳工艺为5倍量的90%乙醇，提取3h。

Results The optimal extract processing of Schizandrin in Schisandra Chinensis was five time volume 90 % ethanol and extracting three times .

辽宁不同产地五味子中五味子乙素的含量测定

A Determination on γ - schisandrin Content within Schisandra Chinensis Gathered from Different Liaoning Origins

粗蛋白、粗灰分、各种氨基酸和五味子甲、乙素含量呈微弱的下降趋势；

Crude protein , crude ash , all sorts of amino acid and contents of schisantherin A and schisantherin B of which tended to reduce faintly ;

前言：目的：五味子中有效成分为五味子乙素，因此我们对该成分进行测定。

Purpose : The main active composition of Schisandra Chinensis Baill is r-schisan-dria , therefore , we conducted determination for the composition .