tnbc

TNBC patients are more likely to have lymph node metastasis ( P0.05 ), and the local recurrence and distant metastasis rates are significantly higher than non-TNBC patients ( P0.05 ) .

提示三阴性乳腺癌有较高的淋巴结转移率。其复发转移率亦明显高于非三阴乳腺癌患者（P0.05）。

The latest studies revealed that the triple-negative breast cancer ( TNBC ) was frequently associated with apparent EMT , but the mechanisms are still unclear .

最新的研究显示，三阴性乳腺癌（TNBC）经常伴随着EMT的发生，但其机制目前尚不清楚。

Results : This study involved 295 cases of breast cancer patients , including 32 cases of TNBC which accounts for 10.85 % and most of its pathological type is invasive ductal carcinoma .

结果：本研究纳入了295例乳腺癌患者，其中三阴性乳腺癌32例，约占10.85%。

The prognosis of TNBC was poor . The factors which were associated with poor prognosis included tumor size , lymph node status , TNM stage . Tumor size and lymph node status were independent prognostic factors .

肿瘤直径、临床分期、淋巴结状态是影响预后的重要因素，其中肿瘤大小和腋窝淋巴结N分期是影响预后的独立危险因素。

TNBC , which accounts for20 percent of all breast cancers , is a very aggressive form of the disease , which has higher rates of metastases and poorer survival rates than other breast cancer subtypes .

在所有乳癌中占百分之二十，是一种侵袭性强的疾病，它与其他乳腺癌亚型相比具有较高转移率和较低生存率。

Compared to other kinds of breast cancer , patience of TNBC can get higher pathologic complete remission and clinical response rates to the neoadjuvant chemotherapy which contains paclitaxel and anthracycline , but also would get lower recurrence-free and overall survival rates .

相对于其他类型的乳腺癌，TNBC对含紫杉类和蒽环类的新辅助化疗有较高的病理完全缓解率和临床反应率，但是无复发生存率及总体生存率低于非TNBC。