tlr4

TLR4 is expected to become a new target for cancer biotherapy .

TLR4有望成为肿瘤生物治疗的新靶点。

TLR4 muscle protein content correlated with the severity of insulin resistance .

肌组织中TLR4蛋白含量与胰岛素抵抗的轻重有联系。

Experimental and Clinical Research of LPS Receptor TLR4 、 CD14 and Inflammatory Response

内毒素膜受体TLR4、CD14与炎症反应的基础与临床研究

The lack of TLR4 in those cells diminishes these effects .

而TLR4缺乏的细胞，这种效应降低。

Deficiency of TLR4 diminished this effect in mice breathing dirty air .

TLR4缺陷小鼠降低了吸入污染空气的影响。

Objective : To study the expression of Toll like receptor 4 ( TLR4 ) in human pancreas .

目的：研究人胰腺组织Toll样受体4（TLR4）的表达分布。

Objective To explore Toll like receptor 4 ( TLR4 ) expression and distribution in rat pancreas .

目的探索Toll样受体4（TLR4）在大鼠胰腺组织的特异性分布表达。

LPS / TLR4 signaling has been intensively studied in the past few years .

在过去的几年里，LPS/TLR4信号通路有了很多研究。

However , it is not known whether insulin-resistant subjects have abnormal TLR4 signaling .

然而尚不清楚胰岛素抵抗者是否有不正常的TLR4信号。

And the mice deficient in the TLR4 receptor showed dramatically lower levels of the cytokines .

并且，缺乏TLR4受体的小鼠，其细胞因子水平明显降低。

Overexpression of TLR2 and TLR4 may induce structural and functional damage to organs .

过度表达的TLR2、TLR4可能造成组织、器官结构和功能损害。

Expression of TLR2 、 TLR4 mRNA in Patients with Atopic Dermatitis

特应性皮炎患者皮损中TLR2、TLR4mRNA的表达

TLR4 and the innate immune response mediated by it are associated with arteriosclerosis .

TLR4及其介导的天然免疫应答与动脉粥样硬化的发生发展存在一定的相关性。

Regulation of the gene expression of TLR4 / MD-2 in endotoxin tolerant macrophages

巨噬细胞内毒素耐受时TLR4/MD-2的基因表达调节作用

Expression of Toll like receptor 4 ( TLR4 ) in human dental pulp cells is regulated by E.coli lipopolysaccharide

大肠杆菌脂多糖影响Toll样受体4在人牙髓细胞的表达

Results Normal human small intestinal and colonic epithelial cells didn 't express TLR4 , CD14and MD2 .

结果人小肠和结肠粘膜上皮细胞TLR4、CD14和MD2均不表达。

TLR4 expression in gastric mucosa with intestinal metaplasia , dysplasia is significantly higher than that in gastric cancer mucosa .

肠化、不典型增生胃粘膜组织TLR4的阳性表达明显高于胃癌组织。

This article reviews TLR4 and the role of TLR4 in the initiation and progression of atherosclerosis .

本文对TLR4及TLR4在动脉粥样硬化的发生和进展中作用的研究作一概述。

Objective To explore the differential expression of Toll-like receptor 4 ( TLR4 ) in human leukocytes and its significance in atherosclerosis .

目的探讨Toll样受体4（tolllikereceptor4，TLR4）在外周血白细胞上的表达及其表达差异在动脉粥样硬化中的意义。

Predication and synthesis of B cell epitopes of human toll-like receptor 4 ( TLR4 ) and determination of its immunogenicity

人TLR4的B细胞优势表位设计、合成及其免疫原性检测

In classic theory LPS activates toll-like receptor 4 ( TLR4 ) in immunity cells and mediates immunology response .

经典的理论是LPS和免疫细胞上Toll样受体4（TLR4）结合，介导免疫反应。

Conclusions Our data indicate that TLR4 may be the LPS signal transducer in endothelial cells and plays important roles in the cell activation of LPS .

结论本研究提示TLR4可能内皮细胞上LPS作用的信号转导分子，在LPS对内皮细胞的激活效应中具有重要的作用；

Besides , the exogenous activation and endogenous ligands in tumor microenvironment may also play important roles in tumor immune escape triggered by TLR4 .

TLR4参与肿瘤免疫逃逸除了外源性活化机制外，肿瘤微环境中的内源性配体同样可能发挥重要作用。

Expression of TLR2 、 TLR4 on peripheral mononuclear cells with the linkage to IL-5 in patients with chronic urticaria

慢性荨麻疹患者外周血单个核细胞TLR2、TLR4表达及其与IL-5的相关性

Ethanol molecules suppress TLR4 's usual ability to send signals that would normally trigger the production of inflammatory cytokines , the authors suggest .

作者提出，酒精分子抑制了TLR4的保护炎症细胞因子的能力。

Background : It has been reported that toll-like receptor 4 ( TLR4 ) is involved in signal transduction of endotoxins .

背景：Toll样受体4（TLR4）在内毒素的信号转导过程中具有重要作用。

Objective To investigate the effects of mechanical ventilation on Toll like receptor 4 ( TLR4 ) in rat ′ s alveolar macrophages ( AM ) .

目的探讨机械通气对大鼠肺泡巨噬细胞（AM）表面Toll样受体4（TLR4）表达的影响。

TLR4 is a newly found transmembrane receptor of LPS , which is responsible for LPS-induced inflammatory cytokines production of inflammatory cytokines .

TLR4是近年新发现的LPS受体，在LPS的胞内信号转导过程中起重要作用。

Conclusion That TLR2 and TLR4 both expressed in human urinary tract epithelium is probably associated with the distribution of uropathogenic bacteria .

结论人尿路上皮细胞中TLR2和TLR4均有表达，尿路感染致病菌分布量可能与TLR亚型表达情况有关。

Objective To explore the relation between human heat shock protein 70 ( HSP70 ) and Toll-like receptor-4 ( TLR4 ) in human monocytes .

目的寻找Toll样受体4（TLR4）新的配体，探讨热休克蛋白70（HSP70）与TLR4的相互关系。