tils

Study of the expressions of Fas and Fasl on tumor cells and Tils in patients with HCC

肝细胞癌患者肿瘤细胞和肿瘤浸润淋巴细胞Fas抗原与Fas配体表达的研究

The failure analysis of glazed TILs die block

釉面砖模板失效分析

Objective To explore the conditions and characterization of tumor infiltrating lymphocytes ( TILs ) isolation and expansion .

目的从肺癌患者手术切除的肿瘤组织中分离出肺癌浸润淋巴细胞（TIL），经rIL2体外激活培养，研究TIL体外分离、增殖的条件和特点。

Methods The TILs acquired number and activity derived from different places of PHCC tissue in12 cases were compared .

方法本实验对12例PHCC肿瘤组织不同部位TIL的得率和成活率进行了比较。

Conclusions : ( 1 ) Low dose irradiation may enhance the anti tumor activity and the number of TILs derived from malignant thoracic fluid .

结论：（1）低剂量照射对胸水TIL具有辐射刺激作用，表现细胞增殖和细胞抗瘤活性增强。

One feature of many solid tumors is the influx of inflammatory cells , such as tumor infiltrating lymphocytes ( TILs ) and macrophages .

许多实体肿瘤中都可以发现炎症细胞浸润，如肿瘤浸润淋巴细胞（TILs）和巨噬细胞。

The augmentation activities of TILs in IL-12 + IL-2 group were higher than that in IL-2 group ( P < 0.05 ) .

IL-12+IL-2组TIL比IL-2组扩增能力明显增强（P<0.05）。

These results indicate that TILs are more suitable to the adoptive immunotherapy of turn or as effector cells than LAK cells .

本研究证明TIL比LAK细胞更适合应用于肿瘤的过继免疫疗法。

Detect the counterattack of lung adenocarcinoma cells and A549 against TILs and protected effect of FasL to TILs ;

检测肺腺癌细胞及腺癌细胞株A549对TIL的杀伤活性及FasL抗体对TIL的保护作用；

The study on the relation between intracellular PFP mRNA expression and antitumor activity in vitro and in vivo of TILs and LAK cells of mouse

小鼠TIL、LAK细胞穿孔蛋白mRNA表达与其抗瘤作用的关系

Objective : To investigate the activities of tumor infiltrating lymphocytes ( TILs ) stimulated by dendritic cells ( DCs ) on mouse breast cancer cells in vitro .

目的：探讨致敏的树突状细胞（DC）激活的肿瘤浸润淋巴细胞（TIL）体外抗小鼠乳腺癌活性。

Conclusions The results indicated that the anti - tumor activities of TILs isolated from primary breast cancer differ from that of TILs isolated from metastatic lymphaden .

结论同一个体乳腺癌其原发癌和转移淋巴结TIL抗瘤活性有差别。

Conclusion : There were a variety of TIDCs and TILs in human melanoma tissue , and those cells could immigrate through high endothelium venule-like blood vessel and lymphatic vessel .

结论人皮肤黑色素瘤组织中存在不同形态的TIDC与TIL，并通过类高内皮微静脉和淋巴管迁移；

TILs could secrete factors that would inhibit the growth of tumor cells when cultured in the presence of rIL-2 . The above observations could help to elucidate the mechanisms of TILs in antitumor defense .

经IL-2培养后的TIL能分泌某种（些）因子抑制肿瘤细胞的生长。上述资料将有助于对TIL的认识和对其抗瘤机理的探讨。

Methods : The proliferation and tumor cytotoxicity of TILs were determined by 3 H-TdR releasing assay . The synergetic effect of TILs and GCM was detected by MTT colorimetric assay .

方法采用3H-TdR释放法检测TILs的增殖及抗肿瘤活性，MTT比色法测定TILs与GCM的协同抗癌作用。

Based on the antigen specific lymphocytes in acute infection tissue can quickly eliminate pathogenic microbial , we hypothesized that induction of acute inflammation in tumor lesions may be capable of rescuing and restoring the effector function of TILs to achieve enhanced antitumor effect .

然而急性感染组织灶中的抗原特异性免疫细胞却能使感染迅速清除。因此，我们提出假设：肿瘤组织引入微生物建立急性炎症环境有可能恢复TIL细胞的抗肿瘤免疫效应。

The results showed that , CD3 + CD4 + and CD8 + lymphocytes scattered in the newly isolated TILs , cultured with low - concentration of rIL-2 in vitro , TILs expressed CD3 + and CDg + predominantly , though CD4 + cells increased significantly .

结果发现新分离TIL中CD3~+、CD4~+、CD8~+较低，体外培养后，TIL中各亚群均有增加，但以CD3~+、CD8~+增加为主；