prx

Effect of ionizing radiation on the expressions of Prx ⅰ and Prx ⅵ gene in murine intestinal epithelial cells

电离辐射对小肠上皮细胞PrxⅠ和PrxⅥ基因表达的影响

Immunohistochemistry was used to observe the distribution of Prx ⅰ and ⅱ in the mouse oviduct and uterus . 2 .

方法：1.免疫组织化学方法观察PrxⅠ和Ⅱ在昆明小鼠输卵管和子宫的分布。

Nevertheless , weak positive expression of PRX 2 was found in the epithelial basal layer cells in normal adult skin but not in dermal tissue .

而在正常成人皮肤中，表皮基底层细胞呈弱阳性表达，真皮组织中未见阳性表达。

Real-time PCR analysis indicated that the Prx showed different expression profiles in shrimp hemocytes and hepatopancreas after artificial infection with Vibrio anguillarum .

实时荧光定量PCR结果显示，弧菌感染后，该基因在对虾血细胞和肝胰脏中的转录水平都有明显变化并且表达模式不同。

Immunohistochemistry analysis display that Prx 1 protein expression was up-regulated in epithelium mucosae of ureter in mice fetus with hydronephrosis .

免疫组化结果显示，Prx1蛋白在肾积水胎鼠输尿管粘膜上皮表达增强。

Results Half of all Prx members had pseudogenes that were the retrotransposons of coding genes and produced according to chronologicaol order .

结果分析表明该家族半数成员具有多个假基因序列，为返转座类型假基因。

Peroxiredoxin ( Prx ) belongs to a peroxidase family of antioxidant enzymes distributed ubiquitously in aerobic organisms .

过氧化物氧还蛋白为广泛存在于需氧生物体的过氧化物酶家族抗氧化蛋白。

CP is the conserved residue that attacks substrates peroxides , and is usually located at the N-terminal region of Prx .

Cp是直接攻击底物过氧化物的残基，在进化水平上非常保守，且通常位于N端。

It was found that many EST and PRX alleles expressed only under salt-stress and a number of salt-induced isozymes appeared .

发现许多EST和PRX等位基因在盐胁迫下表达，产生盐诱导同工酶；

So far researches have focused mainly on Prxs in fish and mammalian , little is known about the existence of Prx in lamprey .

目前关于Prx的研究多集中在硬骨鱼及哺乳动物，七鳃鳗中是否存在Prx尚不明确。

The results indicate that there are close relationships between the changes of EST and PRX isozymegene expression and the genetic salt-stress adaptability in tomato .

实验表明，EST和PRX同工酶表达的变化与番茄对盐胁迫的遗传适应性有密切关系。

It was found that there existed both codominant and silent alleles expressed in the zymograms of EST , PRX and TO .

结果表明，在EST、PRX和TO酶谱中既有共显性等位基因，又有沉默等位基因的表达；

The classification , mechanism of Prx and the research progress on Prx in parasitic helminthes including trematode , cestode and nematode have been briefly reviewed in this article .

本文综述了过氧化物氧还蛋白的分类、作用机制以及寄生性蠕虫（包括吸虫、绦虫和线虫）过氧化物氧还蛋白的研究进展。

Western blotting showed that Prx ⅰ and ⅱ were expressed in the uterus and oviduct , and their levels of expression had no significant differences between diestrus and estrus . 3 .

蛋白免疫印迹技术也显示这两型蛋白在输卵管和子宫均表达，动情期和动情间期这两型蛋白在输卵管和子宫中的表达水平无显著性差异。

Three types of Prx ( I , II , and III ) have been shown to be over-expressed in the case of human breast cancer , and it has been suggested that their over-expressions are related to cancer development or progression .

硫氧还蛋白过氧化物酶Ⅰ、Ⅱ和Ⅲ在人乳腺癌组织中过表达，并与肿瘤的发展和分级相关。

Prx II has been reported to be present in the cytoplasm of RBCs and human umbilical endothelial cells . In a previous study , Prx II is expressed in endothelial cells of benign and malignant vascular tumors in human skin in vivo .

硫氧还蛋白过氧化物酶Ⅱ存在于红细胞及人脐内皮细胞的胞浆中，同时表达于人体表皮肤的良恶性血管瘤。

Results The mRNA and protein expressions of Prx ⅱ in tree shrew HCC tissues were significantly higher than those in para-HCC and pre-HCC tissues , and also higher than those in the liver tissues from the control animals ( all P < 0.05 ) .

结果PrxⅡ在树鼩肝癌组织中的mRNA和蛋白质表达水平均明显高于相应的癌旁和癌前组织，也高于对照组同期活检肝组织（P<0.05）；

Incidence rate congenital hydronephrosis induced by TCDD in C57BL / 6J fetal mice may be cut down effectually by quercetin . Effect of quercetin prevent with congenital hydronephrosis is related with that Prx 1 protein expression is inhibited in epithelium of mucous membrane of fetal ureter .

槲皮素能有效降低TCDD所致胎鼠肾积水的发生率，其对小鼠先天性肾积水的预防作用与抑制胎鼠输尿管粘膜上皮Prx1蛋白表达有关。

Prx isotypes ( I-VI ) are associated with the cellular proliferation , differentiation , and antiapoptotic effect , and their expression is relevant to cancer . Prx II was identified as a thiol-specific antioxidant in the K-562 erythroleukemia cell line and erythrocytes , respectively .

与细胞增殖、分化、抗凋亡及肿瘤相关。研究表明，硫氧还蛋白过氧化物酶Ⅱ在红细胞及K-562红白血病细胞系中作为巯基特异性的抗氧还剂。