pila

Sequencing and bioinformation analysis of type I pili pilA gene of pathogenic Escherichia coli isolated from ducks

鸭源致病性大肠杆菌Ⅰ型菌毛pilA基因序列测定及生物信息学分析

The immunoprotection effect of pilA recombinant protein vaccine was evaluated according to the mortality , re-isolated rate of E. coli , and grades of pathological changes .

coli分离率和各组织器官的病变等级来判定pilA重组蛋白的免疫保护效果。

The Study of Anti-Fimbriae of Type 1 from Avian E.Coli and the Fusion Expression of the Pila Gene and the Immunogenic Study of the Recombinant Fimbriae Proteins

抗鸡大肠杆菌的1型菌毛的单克隆抗体的研究和pilA基因的融合表达及其重组菌毛蛋白免疫原性研究

We also find the C-terminus of PilA possesses cysteine residues that are conserved in type ⅳ pilus of many species , and it forms a disulphide bond that produces a loop , which is important for the function of pilus and also comprises a major antigenic determinant . 2 .

另外，PilA蛋白羧基端拥有相对保守的半胱氨酸残基，该位点能够形成二硫键并产生一个环形结构，在Ⅳ型菌毛发挥功能时起到重要作用，而且是主要的抗原决定部位。