phage display technology

Application of phage display technology in protein researches

噬菌体展示技术在蛋白质研究中的应用

Accompanied the development of phage display technology , the construction of antibody library is becoming matured .

随着噬菌体展示技术的发展，抗体库的构建方案日趋成熟。

Phage display technology is being widely used in cancer research .

随着噬菌体呈现技术的日益广泛应用，其在肿瘤的研究中也发挥了越来越大的作用。

Objective To construct human antibody gene library with phage display technology .

目的构建胶质瘤患者人源性噬菌体抗体基因库。

Phage display technology has been applied in many biotechnological fields .

噬菌体表面呈现技术已被广泛地应用于生物技术的许多领域。

Phage display technology is an ideal approach to the study on the protein evolution .

噬菌体展示肽库技术是研究蛋白质分子进化的理想工具。

The screen of anti-melanoma single chain antibody by phage display technology

噬菌体呈现技术筛选抗黑色素瘤单链抗体

Expression of Anti-RBC Blood Group B Substance ScFv by Using Phage Display Technology

用噬菌体呈现技术表达抗人红细胞血型B抗原的单链抗体

Generation of Human Monoclonal Antibody Fab Fragment to Rabies Virus by Phage Display Technology

人源抗狂犬病毒单克隆抗体Fab段基因的获得和表达

Objective To search for new antigens expressed on the surface of thymic stromal cells using phage display technology .

目的利用噬菌体展示技术寻找胸腺基质细胞表面的新抗原。

In this paper , phage display technology was used to screen scFv against HrpA .

通过噬菌体展示技术淘选抗细菌HrpA蛋白的单链抗体。

Human monoclonal antibody Fab fragments to HIV 1 have been prepared by using phage display technology .

应用噬菌体抗体库技术有效地筛选出了多株抗HIV1人源单克隆抗体。

Generation of anti-rhEPO ScFv by using phage display technology

用噬菌体表面表达技术筛选及表达抗重组人促红细胞生成素单链抗体ScFv

This review focuses on the application of phage display technology in the prevention , diagnosis and treatment of parasitic diseases .

本文介绍丝状噬菌体展示技术及其在寄生虫病预防、诊断和治疗中的应用。

Phage display technology , which is an important tool for the high affinity Antibody , can make human antibody without immunization .

抗体库技术为制备高亲和性的人源抗体提供了有力工具。

The successful preparation of specific antibodies against MM cells by phage display technology paves the way for further study and application .

在本研究中，我们采用噬菌体抗体库技术，成功地从1例长期带瘤生存的MM患者体内克隆到特异性抗MM细胞的抗体，为进一步的研究和应用奠定了基础。

By using phage display technology , 12-mer peptide ligands that bind specifically to mouse embryonic stem cells were isolated .

本实验利用噬菌体展示技术，得到了九条能与小鼠胚胎干细胞特异性结合的十二肽。

Construction of Single-chain Light Variable Region ( ScV_L ) Library of Chicken IgY Genes by T7 Phage Display Technology

鸡IgY轻链可变区（ScVL）基因T7PDT文库构建

This review will focus on the application of phage display technology in epitope studies and its potential application in the development of novel diagnostic reagents and vaccines .

本文将集中回顾一下噬菌体展示技术在抗原决定族定位研究中的应用，及其在新型诊断试剂和疫苗开发中的潜在前景。

A dodeca-peptide SVSVGMLPSHAP that targets human CL-187 tumor was identified in vivo by phage display technology .

利用噬菌体展示技术，对荷人结肠癌CL-187裸鼠进行体内筛选，获得在肿瘤组织中富集的一条十二肽SVSVGMLPSHAP。

METHODS : The ScFv gene library was constructed by phage display technology . The affinity to antigen was detected by ELISA after panning .

方法：利用噬菌体表面呈现技术，构建基因文库，经过panning筛选富集后，用ELISA方法检验抗原结合活性。

Peptides possess not only appropriate pharmacokinetic properties to serve tumor imaging or therapeutic targeting agents , but also easily deduce peptide residues using phage display technology .

肽作为肿瘤显像剂和导向治疗靶试剂不仅具有药物代谢动力学的优势，而且利用噬菌体展示技术易于得到肽序列。

The genes of anti-HBsAg Fab antibody were obtained from human peripheral blood lymphocytes of volunteer with high antibody titer to HBsAg by using of phage display technology .

通过噬菌体展示技术从含高滴度抗乙肝表面抗原（HBsAg）抗体的人外周血淋巴细胞获得抗HBsAgFab抗体的轻、重链基因。

Antibody phage display technology has been described as the third revolution in antibody technology . The key of this technology was the construction of large , highly specific and sensitive antibody libraries .

噬菌体呈现抗体库技术被誉为抗体技术的第三次革命，发展构建库容量大、特异性高和敏感强的人源性抗体库是噬菌体呈现技术的关键。

Therefore , it has certain innovative that the broad-spectrum chemokine inhibitors in vitro screening which made a variety chemokines as targets by using phage display technology . Methods : 1 .

因此，利用噬菌体展示技术，以多种趋化因子为靶标进行的广谱趋化作用抑制剂的体内筛选具有一定的创新性。

The Phage display technology ( PDT ) is technology that expresses exogenic polypeptide with shell protein of phage by inserting the exogenic DNA into the shell gene .

噬菌体展示技术是一种有效的药物靶点筛选工具，可用其筛选中药的药物靶点蛋白。

Using phage display technology , cDNA library of anti - adipocyte membrane scFv was constructed from mRNA of mice spleen cells , which had been immunized by pig adipocytes .

应用噬菌体展示技术，从猪脂肪细胞免疫的小鼠脾细胞mRNA中构建出单链抗体（scFv）cDNA文库。

Conclusion Both epithelial cells and dendritic cells are highly heterogeneous in thymic medulla . Phage display technology can be used as a powerful tool in searching for new antigens on thymic stromal cells .

结论胸腺髓质上皮细胞和胸腺树突状细胞均具有异质性，同时噬菌体展示技术可以作为寻找细胞表面新分子的强有力工具。

The best advantage of in vivo phage display technology was able to obtain targeting peptide , which can combine with living tissue or organ specifically and have a relatively higher stability and specificity in vivo .

噬菌体展示技术体内筛选方法的最大优点是能够得到特异性结合活体组织、器官等靶标并在体内具有较好的稳定性和较高特异性的小肽。

Objectives : To screen small peptides that could antagonize the PGE2 receptor in rheumatoid arthritis ( RA ) by phage display technology , so that a new way could be found for the treatment of RA .

目的：通过噬菌体技术筛选PGE2受体拮抗剂，探讨其在类风湿性关节炎（Rheumatoidarthritis，RA）中的作用，为RA的治疗开辟新的途径。