perilymph

OBJECTIVE To establish a method for determining the concentration of dexamethasone phosphate in the perilymph of guinea pig .

目的建立豚鼠外耳淋巴液中磷酸地塞米松的含量测定方法。

Variations in round window membrane permeability and in perilymph flow could account for why hearing losses are observed in some patients .

圆窗膜通透性的变化和外淋巴液流动的变化可以解释为什么在某些患者观察到听力损失。

The effects of noise on the contents of some ions in cochlear perilymph

噪声对耳蜗外淋巴中某些离子含量的影响

The Primary Study of the Perilymph Drainage to Cervical Lymph Nodes in Guinea Pigs

豚鼠外淋巴至颈淋巴结引流途径初步观察

Ferrum in serum and perilymph were not significant between groups .

各组间血清铁和外淋巴铁无显著差异，SAGM对肾功能无明显影响。

Perilymph Ions Changing of Cochlea in Guinea Pig with Acute Purulent Otitis Media

急性化脓性中耳炎对耳蜗外淋巴离子的影响

Effect of adenosine on perilymph glutamate concentration and compound action potentials in guinea pigs exposed to white noise

腺苷对噪声暴露豚鼠耳蜗谷氨酸和复合动作电位的影响

Relationship of distribution of danshensu in blood , cerebrospinal fluid and perilymph fluid with noise-induced deafness

丹参素在豚鼠血液、脑脊液和外淋巴液中的分布与噪声性耳聋的关系

The Distribution of Gentamicin in the Hair Cells of the Inner Ear Following Gentamicin Application Through Endolymph or Perilymph Approach

庆大霉素经过内、外淋巴途径给药后在内耳毛细胞中分布的比较

The effect on SOD content in cochlea perilymph of guinea pigs with the kanamycin ototoxicosis

卡那霉素内耳中毒对豚鼠外淋巴液中SOD含量的影响

The effect of less perilymph in the scala tympani on excitability of auditory nerve in guinea pig

外淋巴枯竭状态对听神经兴奋性影响

Objective To observe the effect of noise on the concentration of glutamate in perilymph and cochlear potential of guinea pig cochlear .

目的观察噪声暴露对豚鼠耳蜗外淋巴液中谷氨酸含量及耳蜗电位的影响。

The Effects of Potassium and Sodium in Perilymph on the Endocochlear Potential ( EP ) in Guinea Pig

外淋巴钠、钾离子浓度对豚鼠蜗内电位的影响

The quantitative assay of zn 、 cu 、 ca 、 cu / zn in perilymph of inner ear in foetus

胎儿内耳外淋巴锌、铜、钙定量分析

Results After topical administration or intracardial injection of DEX , concentrations of drug in perilymph and plasma decreased gradually over time .

结果圆窗或心内注射给药后，豚鼠外淋巴液、血浆中的DEX浓度随时间的延长呈逐渐下降的趋势；

Methods Cochlear action potentials , cochlear hair cell counts , and GM concentrations in blood and perilymph were tested for the following experiments .

方法听神经动作电位测试技术，全耳蜗毛细胞计数定量观察技术和荧光偏振免疫法测定庆大霉素浓度的技术被用于以下两个不同目的的实验观察。

Potassium and sodium ion concentration of the endolymph and perilymph in endolymphatic hydrops of the guinea pig

膜迷路积水豚鼠的内、外淋巴液钾、钠离子浓度

Objective To investigate the distribution of ligustrazine hydrochloride in guinea pig blood , cerebrospinal fluid and perilymph fluid afte intramuscular injection .

目的测定肌肉注射盐酸川芎嗪注射液后川芎嗪在豚鼠血液、脑脊液和耳蜗外淋巴液中的分布。

The concentrations of nifedipine in perilymph of guinea pig range from 50.2 ng / ml to 124.2ng/ml .

外淋巴液硝苯地平的浓度为50.2~124.2ng/ml。

Peak concentrations and gradients for gentamicin varied considerably between animals , likely resulting from variations in round window membrane permeability and rates of perilymph flow .

庆大霉素的峰值浓度和浓度梯度在动物之间的差异相当的大，这可能是由圆窗膜通透性的不同和外淋巴液流动率的不同所导致的。

AIM : To measure the content of danshensu in guinea pig blood , cerebrospinal fluid and perilymph fluid of cochlea after injection with danshen injection .

目的：测定给豚鼠肌注丹参注射液后血液、脑脊液和耳蜗外淋巴液中丹参素的含量。

Determination of the Content of Dexamethasone Sodium Phosphate in the Scala Tympani Perilymph and Blood Plasma in Guinea Pigs after Intracardiac Injection of the Drug

豚鼠心内注射给药后外耳淋巴液和血浆地塞米松磷酸钠的浓度测定

Conclusion : The sensibility of the method is high , accurate , and repeatable . It can be used to determine the content of dexamethasone sodium phosphate in perilymph .

结论：该法灵敏度高，准确性、重复性好，可用于外淋巴液中磷酸地塞米松的测定。

Experimental Study on the Therapeutic Value of Oxytocin on Hearing Loss due to Kanamycin The effect on SOD content in cochlea perilymph of guinea pigs with the kanamycin ototoxicosis

催产素改善卡那霉素所致听力损伤的实验研究卡那霉素内耳中毒对豚鼠外淋巴液中SOD含量的影响

The high concentration of K + in endolymph and the circulation of K + in both endolymph and perilymph are the basis of maintaining cochlear function and homeostasis .

内淋巴中高浓度的K+聚积及内、外淋巴液中K+循环是维持耳蜗功能和内环境稳定的基础。

It decreased to low level 70 min after injection . The ligustrazine hydrochloride could be found in perilymph fluid 5 min later . Its high level in 20 min was 215.79 ug / ml.

在耳蜗外淋巴液中5min时能检测到川芎嗪，50min时浓度达最大值（215.79μg/ml），70min后药物浓度明显降低。

Objective : To determine pharmacokinetics profiles of dexamethasone ( DEX ) in perilymph of guinea pig with different intratympanic administrations , and to provide experimental evidence for clinical choice about administration .

目的：分析不同方式鼓室内给药后豚鼠耳蜗外淋巴液中地塞米松（DEX）代谢动力学特征，为临床选择鼓室内给药方式提供实验依据。

In the inner ear , there are distribution of a lot of Na + / K + ATP-ase , which plays an important role in maintaining ion homeostasis and the large cation gradients that exist between the endolymph and the perilymph .

在内耳中，同样分布着大量的Na+/K+-ATP酶，其对维持内、外淋巴钾离子梯度及各细胞功能稳定起着重要作用。

Methods The HPLC was used for determination of ligustrazine hydrochloride in guinea pig blood , cerebrospinal fluid and perilymph fluid afte intramuscular injection by internal and external standard method . Results Ligustrazine hydrochloride could be absorbed into blood rapidly after intramuscular administration in guinea pig .

方法豚鼠经肌肉注射盐酸川芎嗪注射液（2ml/kg）后，采用高效液相色谱法（HPLC）中的内标法和外标法测定血液、脑脊液和耳蜗外淋巴液中川芎嗪的浓度。