pericyte

The relation between TGF β _1 and pericyte in angiogenesis of breast cancer

TGFβ1与周细胞在乳腺癌血管生成中的关系及意义

Objective To observe the morphological character of pericyte , meanwhile , to find the marker of pericyte .

目的观察周细胞形态特点，并寻找其标记物。

Advances in research on the molecular biology mechanisms of diabetic retinal pericyte cell apoptosis

糖尿病视网膜毛细血管周细胞凋亡分子生物学机制的研究进展

Objective : To study the pericyte of angiogenesis in granulation tissues .

目的：研究周细胞在肉芽组织血管生成过程中作用。

AIM : To explore the selective culture method of bovine retinal capillary pericyte in vitro .

目的：探讨牛视网膜毛细血管周细胞（pericyte，PC）的体外选择性培养方法。

Effect of hypoxia , bFGF and VEGF on proliferation of bovine microvascular endothelial cell and pericyte

缺氧、bFGF和VEGF对牛视网膜血管内皮细胞和周细胞增殖的影响

The effect of retinal pericyte conditioned medium on proliferation of RPE cells , glial cells and macrophage

周细胞条件培养液对视网膜色素上皮细胞、胶质细胞及巨噬细胞增殖的影响

Rat retina digest preparations were observed by light microscope , and the number of pericyte was counted .

动物活体灌注固定，视网膜消化铺片，光镜观察，计数周细胞并行统计分析。

Diabetic rats showed pericyte decrease and capillary basement thickening in deep capillary bed of retina after 6 months follow-up .

成模6月后，视网膜深层毛细血管呈现周细胞减少、基底膜增厚的特征性改变，而成模4月时，电镜显示糖尿病大鼠深层毛细血管基底膜增厚。

Advances in research on diabetic retinopathy have confirmed that pericyte apoptosis precedes the selective loss of diabetic retinal pericyte cells .

随着糖尿病视网膜病变研究的进展，已证实糖尿病视网膜毛细血管周细胞的丧失是由细胞凋亡所引起的。

Stereoscopy Analysis showed that , in breast cancer , there are positive correlation between area of TGF β 1 mRNA expression and area of pericyte .

乳腺癌中TGFβ1mRNA的表达与周细胞的表达正相关，P<001。

Hypoxia leads to DNA injury , an increase in oxygen free radicals , and a low expression of the Bcl-2 , which then causes pericyte cell apoptosis .

低氧则引起视网膜毛细血管周细胞DNA损伤、氧自由基的产生增加、细胞凋亡抑制基因Bcl-2的低表达，导致细胞凋亡。

Results : After six months , the STZ diabetic rats retinal digest preparations showed characteristic retinal changes including decrease of pericytes , capillary microaneurysms , acellular capillary and ghost pericyte .

结果：糖尿病大鼠存在明显的高凝、高粘现象，并出现了周细胞减少、微血管瘤、无细胞毛细血管及影周细胞等特征性糖尿病视网膜病变；

The retinal digest preparations of the STZ-diabetic rats showed characteristic retinal changes of early diabetic retinopathy , including decrease of pericytes , microaneurysm , acellular capillary and pericyte ghost .

糖尿病6个月时模型组大鼠的血液有高凝、高粘现象，并出现了影周细胞、周细胞减少、微血管瘤等早期糖尿病性视网膜病变的特征性改变。

Pericyte / endothelial cell ratio is 0.755.4 Immunohistochemical staining of retinal capillary showed that retinal vascular with a brown positive , artery and vein were stained deep and the microvascular with a shallow staining .

4视网膜毛细血管铺片免疫组织化学染色：可见视网膜血管呈现棕黄色阳性着染，动静脉染色深，微血管染色浅。

CONCLUSION : There are changes of retinal capillary endothelium and pericyte at the early period of diabetic retinopathy , and the capillary basement membrane is thickened , it is further aggravated with the process of disease .

结论：当糖尿病视网膜病变早期即出现视网膜内皮细胞及周细胞的改变，且基底膜增厚，随着病程延长病变进一步加重。

At the 6th month , apoptosis was increased significantly . The pericyte number of control group and DM_6 group were 5.66 ± 0.60 and 6.52 ± 0.40 respectively , and there was obvious difference ( P < 0.01 ) .

6月时细胞凋亡呈增加趋势，DM6组及对照组周细胞数分别为（5·66±0·60）个及（6.52±0.40）个（P<0.01）；

After passage , pericyte growth is accelerated , with a growth period characterized by a logarithmic function on the third day and a flat period on the tenth day . The capitalists of our times continued vigorously to cultivate white chauvinism .

传代培养后增长速度明显加快，第3天进入对数生长期，第10天进入平台期。当代的资本家继续卖力地培养白种沙文主义。

D α tocopherol achieved a complete prevention of augmented pericyte and endothelial cell profile areas and basement membrane thickening in the superficial and deep capillaries bed of diabetic retina but had no effect on blood glucose and HbA 1c .

Dα生育酚可显著改善糖尿病视网膜微血管周、内皮细胞截面积和深浅层毛细血管基底膜厚度，而对血糖、HbA1c无影响。

Digest preparation . 1 ) With GK rats grow up , there is significant difference in the ratio of endotheliocyte and pericyte ( E / P ) of blood capillary of the GK rats ( P < 0 01 ) .

消化铺片1）GK大鼠随着月龄增加毛细血管内皮细胞与周细胞的比值（E/P）增大，差别有统计学意义（P<0.01）。