p65

Telomerase reverse transcriptase and nuclear factor kappa B / p65 expression in human laryngeal squamous cell carcinoma

端粒酶逆转录酶与核因子κB/p65在喉鳞状细胞癌中的表达

Expression and clinical significance of Bcl-2 and NF - к B / p65 in diffuse large B-cell lymphoma

Bcl-2与NF-κB/p65在弥漫性大B细胞淋巴瘤中的表达及意义

Effect of burn serum on the nuclear translocation of monocytic NF - κ B p50 / p65

烧伤患者血清对单核细胞核因子κB核移位的影响

The protein levels of NF κ B ( P65 ) and Caspase 3 in cancer cells were observed by SP immunohistochemistry .

SP免疫组化法检测细胞内NF-κB蛋白（P65）、caspase-3蛋白表达水平。

EGCG also suppressed the nuclear translocation in NF - κ B ( p65 ) and I κ B α phosphorylation .

EGCG能抑制NFκB（p65）的核移位，并抑制IκBα的磷酸化。

The expression rate of Bcl-2 and NF - κ B / p65 proteins in DLBCL have relation with clinical staging , effect and prognosis .

Bcl-2与NF-κB/p65蛋白在DLBCL中的表达与临床分期、疗效及预后有关。

The expression level of NF - κ B ( p65 )? FAK and the level of phosphorylated FAK were assessed by Western blot analysis .

westernblot法分析NFκB（P65）、FAK的表达及FAK酪氨酸磷酸化水平。

Result : There is significant difference between the laryngeal carcinoma group and vocal cord polyps group about NF - κ B / p65 and COX-2 protein expression level .

结果：NFκB/p65和COX2蛋白在喉癌组与对照的声带息肉组比较有显著性差异。

NF - κ B / p65 in cell suspension was measured by immunochemical staining , positive rate was calculated and its correlation with the cytokine levels was analyzed .

细胞悬液用免疫组化染色检测NF-кB/p65，显微镜下计算其阳性细胞率，并分析二者的相关性。

Over-expression of NF - κ B / p65 was related to lymph node metastasis and depth of invasion , it may be related to cancer cell invasion and metastasis .

NF-κB/p65在有淋巴结转移和浸润至深肌层的宫颈癌组织中高表达，可能与肿瘤细胞侵袭转移有关。

The expression rates of Bcl-2 and NF - κ B / p65 proteins in DLBCL were 51.5 % and 38.7 % . There was significant correlation between them ;

结果Bcl-2和NF-κB/p65蛋白在DLBCL中的表达率为51.5%和38.7%，二者表达有相关性；

Objective To explore the effects of interleukin-6 ( IL-6 ) on the activity of nuclear factor kappa B p65 ( NF - κ B p65 ) in HL-60 cells .

目的研究白细胞介素6（interleukin-6，IL-6）对粒细胞白血病细胞系HL-60核因子-κBp65（NF-κBp65）活性的影响，以探讨IL-6在白血病发生、发展中的作用。

Having stimulated by AGE-BSA for 15 min , NF - κ B / P65 translocated into nucleus , and reached to the peak in 30 min.

经AGE刺激后NF-κB/P65迅速核转位，30min达高峰。

In ovarian benign epithelial tumors , borderline epithelial tumors and malignant epithelial tumors , the positive rates NFkB / P65 were 33.3 % , 37.5 % and 65 % respectively .

2在卵巢良性上皮性肿瘤、卵巢交界性上皮性肿瘤和卵巢癌中NFkB的阳性表达率分别为33.3%、37.5%和65.0%；

Results The soluble GST-polypeptide fusion protein and the p50 / p65 proteins with DNA binding activity were obtained . Three polypeptides could interact with p50 protein identified by GST pull-down assay .

结果经诱导表达获得了可溶性的GST-多肽融合蛋白和具有DNA结合活性的p50p、65蛋白，GSTPull-down实验证实3条多肽与p50发生特异地相互作用。

Detection expression of NF - κ B / p65 may be of value in further understanding the biological behavior of cervical carcinoma , NF - κ B / p65 is likely to be a target molecule in clinical therapy .

检测宫颈癌中NF-κB/p65表达有助于进一步探讨宫颈癌生物学行为，NF-κB/p65有望成为抗宫颈癌临床治疗新的靶分子。

Conclusion Irradiation with both low dose and high dose of X-rays can induce the increase of the DNA binding activity of NF - κ B predominantly heterodimer p65 / 50 in peritoneal macrophages in irradiated mice .

结论：高、低剂量X射线诱导小鼠腹腔巨噬细胞转录因子NF-κB的DNA结合活性增强以异源二聚体p65/50增强为主。

Methods The growth inhibitory rate was evaluated by MTT assay . Apoptotic rate was determined by flow cytometry . The expression of wild type P53 , Bcl-2 and NF - κ B ( P65 ) proteins were detected by immunohistochemical staining .

方法采用MTT法检测癌细胞增殖抑制率，流式细胞仪检测细胞凋亡率，免疫组化检测野生型P53、Bcl-2和NF-κB（P65）蛋白表达。

Objective To evaluate the expression of nuclear factor kappa B ( NF - к B ) p65 in relation to angiogenesis microvessel density ( MVD ) and clinical outcomes in adenoid cystic carcinoma of salivary glands ( ACCs ) .

目的检测涎腺腺样囊性癌（ACCs）中核因子кB（NF-кB）p65的蛋白表达水平和微血管密度（MVD），并探讨二者与ACCs临床病理及预后的关系。

The study showed NAC can down-regulate the NF - κ B translocation . Conclusion Through the regulation of redox balance , NAC influences the NF - κ B p65 ′ s translocated nuclear import so as to inhibit TNF - α′ s release , relieve the liver injury .

结论NAC可能通过调整库普弗细胞氧化还原平衡，影响NFκBp65活化（核易位），从而抑制了TNFα等炎性因子基因的表达，减轻肝损伤。