nya

And NYA could increase the expression at 24 h obviously .

而脑溢安在第24h即明显增强大鼠脑内HO1表达。

But we all wish you and nya many years of happiness , and many sons too .

但是我们希望你和尼娅永远快乐，儿孙满堂。

Conclusion : NYA promotes the recovery of neurological deficits , increases the hematoma absorption ;

结论：NYA能促进神经功能恢复，加快血肿吸收；

Nya is not just another women .

尼娅不仅仅是另一个女人。

Nao yi-an ( NYA ) is a kind of traditional Chinese medicine treating ICH ( acute stage ), and had valid clinical effect .

脑溢安（Naoyi-an，NYA）是治疗脑出血（急性期）的国家三类中药新药，临床疗效确切；

Objective : To explore the mechanism of Naoyian granule ( NYA ) in treatment of intracerebral hemorrhage ( ICH ) .

目的：探讨脑溢安颗粒剂（NYA）治疗脑出血的作用机制。

The distribution and expression difference of BDNF ^ GDNF in the ICH rat brains and effect of NaoYiAn ( NYA ) have been investigated by immunohistochemistry technique .

应用免疫组化技术研究脑出血大鼠脑内BDNF、GDNF在脑出血后分布、不同时间点的表达差异以及脑溢安对其表达的影响；

Objective To study expression change of vascular endothelial growth factor ( VEGF ) protein and mRNA in rat brain with cerebral hemorrhage and effect of traditional Chinese medicine complex Nao Yi An ( NYA ) on VEGF expression .

目的研究实验性脑出血大鼠脑内血管内皮生长因子（VEGF）的时空分布及中药脑溢安的影响。

Objective To study the effects of Nao Yi An ( NYA ) serum on the expression of vascular endothelial growth factor ( VEGF ) gene in cultured rat cerebral microvascular endothelial cell ( BMEC ) with hypoxia .

目的观察脑溢安血清对体外缺氧培养的大鼠脑微血管内皮细胞血管内皮生长因子（VEGF）基因表达的影响。

VEGF protein was increased by hypoxia in cerebral microvascular endothelial cells ( P < 0.05 ) . The content of VEGF protein in NYA serum containing medium was more significantly elevated than those cultured in other control media ( P < 0.01 ) .

缺氧损伤的脑微血管内皮细胞内VEGF蛋白表达增强，脑溢安血清组VEGF蛋白的表达水平高于对照组（P<0.01）。

Objective To investigate the effects of the traditional Chinese medicine complex nao yi an granule ( NYA ) on the expression of heme oxygenase 1 ( HO 1 ) in the brains of intracerebral hemorrhagic ( ICH ) rats .

目的：探讨脑溢安对脑出血后含铁血红素氧合酶1（HemeOxygenase1，HO1）表达的影响。

Objective To investigate the effect of NYA granule , a national new class agent , on protein and mRNA expression of bFGF in rat brain following intracerebral hemorrhage and supply theoretic evidence of NYA treating intracerebral hemorrhage and promoting rehabilitation of neural function .

目的探讨国家三类新药脑溢安颗粒（NYA）对脑出血大鼠脑内碱性成纤维因子（bFGF）蛋白和mRNA表达的影响，从而为治疗脑出血，促进神经功能的修复提供理论依据。

Methods : Experimental ICH model rats were established by stereo-locating injection of collagenase method . Cell morphologic ex - amination , DNA fragmentation rate and flow cytometry were used to observe the effects of NYA on neuronal apoptosis of hippocampal capsula internal ( CAI ) region and cerebral cortex .

方法：用立体定位注射胶原酶方法，采用细胞形态学，DNA裂解率及流式细胞仪技术，观察脑溢安颗粒剂对出血性中风大鼠海马CA1区及皮质神经细胞凋亡的影响。