miru

MIRU genotyping method is useful to study the cause of tuberculosis recurrence .

MIRU分型方法是研究结核病复发原因的可行方法。

The 81 Beijing genotype strains could be subdivided into 39 different MIRU genotypes .

81株北京基因型菌株可以分为39种不同的MIRU基因型。

Especially MIRU typing that is easy to popularize will exert important function in the epidemiological investigation of tuberculosis .

尤其是MIRU技术，便于普及，可以在结核病流行病学调查研究上发挥重要作用。

It can be divided further with genotyping methods , such as mycobacterial interspersed repetitive unit ( MIRU ) typing .

它可进一步用基因分型方法划分，如结核分枝杆菌散在重复单位（MIRU）分型。

Based on the MIRU genotypes , 13 of all 16 recurrent drug-resistant patients were reinfected with new drug-resistant strain of Mycobacterium tuberculosis .

在16例复发耐药患者中，13例患者在两次发病时分离的菌株基因型不一致，可能是由于重新感染了耐药菌株所致，属于原发性耐药。

Mycobacterial interspersed repetitive units ( MIRU ) genotyping was performed and analyzed on pairs of isolates of Mycobacterium tuberculosis from 16 recurrent patients with drug-resistant tuberculosis .

并对16例复发耐药患者前后发病菌株进行结核分枝杆菌散在分布重复单位（mycobacterialinterspersedrepetitiveunits，MIRU）基因型比较分析。

All isolates were typed by mycobacterial interspersed repetitive units ( MIRU ) and deletion-targeted multiplex PCR ( DTM-PCR ) .

所有的菌株均采用了结核分枝杆菌散在重复单位分型方法（MIRU）和定向缺失多重PCR（DTM-PCR）。

Results Of 37 qualified patients with recurrent tuberculosis , the isolates from 25 patients in their two tuberculosis episodes showed different MIRU patterns , indicating that 68 % recurrent patients were due to exogenous reinfection .

结果在37例符合要求的结核病复发患者中，25例患者两次发病时MIRU基因型发生了变化，提示68%的结核病患者复发是由于外源性再感染而引起的。