ht4
ht4
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Objective : To examine the effects of 5 HT4 receptor partial agonist tegaserod on response to rectal distention ( RD ) and on nNOS expression in spinal cord , and to investigate the mechanism of tegaserod influencing visceral sensation .
目的:观察应用5HT4受体部分激动剂替加色罗(tegaserod)对大鼠直肠扩张反应的影响和脊髓神经元性一氧化氮合酶(nNOS)表达的变化,探讨替加色罗对内脏感觉的影响机制。