ghrh

The Construction of GHRH Gene Expression Vector Based on RNA Replicon and Its Expression in 293 Cell

基于RNA复制子GHRH基因表达载体的构建及在293细胞中的表达

Cloning , Sequencing Analysis on GHRH Gene on Yak

牦牛生长激素释放激素基因的克隆及序列分析

Cloning and sequence of GHRH gene of porcine hypothalamus

猪下丘脑促生长激素释放激素（GHRH）基因克隆及序列分析

Expression and Bioactivity Analysis of a Fusional Protein which Consists of HSA and GHRH

生长激素释放激素&白蛋白融合蛋白的克隆表达和活性鉴定重组人白蛋白融合干扰素在毕赤酵母中的表达及稳定性研究

Expression of gsp Oncogenes in Human Somatotrophinomas and Their Correlation with Effects of GHRH on Growth Hormone Secretion

gsp癌基因在人垂体生长激素腺瘤的表达及与GHRH对生长激素分泌效应比较

The above suggests that the GHRH provocative test has great significance in the diagnosis and treatment of the patients with GH deficiency disease .

提示GHRH激发试验对明确诊断和指导治疗有重要意义。

Objective To study the effects of dexamethasone and growth hormone releasing hormone ( GHRH ) on growth hormone ( GH ) cell differentiation .

目的探讨糖皮质激素和生长激素释放激素（GHRH）对大鼠胚胎垂体生长激素（GH）细胞分化的作用。

TPA enhanced GHRH releasing effect on adenoma cells with gsp positive , but in vain on gsp negative ones .

TPA可增强GHRH对gsp阳性表达腺瘤细胞分泌的刺激作用，但是对阴性组细胞无此作用。

After 30 days , the plasmic level of CRH , ACTH and cortex ketone increased , GHRH decreased and GH had no obvious change .

间断低氧30d后，血浆CRH、ACTH，皮质酮均升高，GHRH降低，而生长激素没有明显变化。

GH is regulated by two hypothalamic neuropeptides : inhibitory somatostatin ( SS ) and stimulatory GH-releasing hormone ( GHRH ) .

腺垂体GH受下丘脑分泌的生长抑素（SS）和生长激素释放激素（GHRH）的双重调节。

Objective : To prolong the half-life of growth hormone releasing hormone ( GHRH ) by constucting human serum albumin ( HSA ) - GHRH fusion protein .

目的：通过与人血清白蛋白（HSA）融合，延长生长激素释放激素（GHRH）在体内的半衰期。

Growth hormone releasing hormone ( GHRH ) is a peptide hormone secreted from thalamencephalon , which can induce the releasing of human growth hormone ( hGH ) .

生长激素释放激素（growthhormonereleasinghormone，GHRH）是一种下丘脑分泌的肽类激素，具有诱导hGH释放的作用。

Purpose To investigate Gs α and growth hormone releasing hormone receptor ( GHRHR ) mutation and the possible role of GHRH in the formation of human pituitary somatotroph adenoma .

目的探索Gsα和生长激素释放激素受体（GHRHR）基因突变和生长激素释放激素（GHRH）在生长激素瘤形成中的作用。

This article reviewed the development of GHRH analogs about many aspects respectively such as its recognition , synthesis and analysis method of biological activity , the relationship with diabetes mellitus and the treatment situation of diabetes mellitus using GHRH analogs .

本文对GHRH类似物的认识、合成、活性分析方法，与糖尿病的关系，以及GHRH类似物应用于糖尿病的研究现状进行了逐一论述。

Growth hormone ( GH ) provocative test was done by intravenous injection of growth-hormone-releasing hormone ( GHRH ) in 31 children with GH deficiency disease ( male 21 , female 10 ; age 3.6 ~ 16 yr ), and the levels of GH were measured by radioimmunoassay .

应用体外静脉注射生长激素释放激素（GHRH）对31例生长激素缺乏症病儿（其中男21例，女10例，年龄3.6～16岁）进行激发试验，并进行生长激素（GH）放射免疫测定。

This peptide is very sensitive to the degeneration of enzyme , especially the dipeptidyl peptidase ⅳ ( DPP ⅳ) . Protein hydrolyzation mediated by dipeptidyl peptidase ⅳ ( DPP ⅳ) is the mainly cause resulting in the degeneration and invalidation of GHRH in vivo .

该肽对酶降解十分敏感，特别是对二肽酶Ⅳ（DPPⅣ）最为敏感，二肽酶Ⅳ（DPPⅣ）介导的这种蛋白水解作用是GHRH在体内降解、失活的主要途径。