everolimus

CONCLUSION : The used rat model offers the opportunity to study the influence of everolimus on the interaction of humoral and cellular mechanisms involved in chronic renal damage .

结论：该大鼠模型研究慢性肾脏破坏体液和细胞机制，并研究依维莫司与其的交互作用。

As with other immunosuppressive therapies , everolimus is linked to a potential risk for serious infection and malignant tumors , such as lymphoma .

与其他免疫抑制剂治疗组相比，依维莫司于严重感染和恶性肿瘤发生的危险，如淋巴瘤，表现为正相关。

Because of these safety concerns , a risk evaluation and mitigation strategy has been implemented to educate patients and clinicians regarding the safe use and risks of everolimus .

基于这些安全性的考虑，研究者们正在进行一些危险评估和缓解策略，从而对患者和临床医生进行依维莫司安全使用和危险因素的相关教育。

Some new immunosuppressive drugs , such as Rapamycin and Everolimus , can not only inhibit the acute transplant rejection but also prevent cardiac vasculopathy .

雷帕霉素和Everolimus等新型免疫抑制剂在有效抑制急性排斥反应的同时还可预防移植物心血管病变，显示出较好的应用前景。

Everolimus is also approved under an alternative trade name , Zortress , for prophylaxis of organ rejection in adult patients at low-moderate immunologic risk receiving a kidney transplant .

另外，已被批准的依维莫司的其他商品名为Zortress，用于预防接受肾移植并伴有低级至中级免疫学风险的成人患者的器官排斥。

Also , the rate of peripheral edema , dyslipidemia , and hyperlipidemia was5 % higher in those receiving everolimus and low-dose cyclosporine compared with mycophenolic acid and full-dose cyclosporine .

与麦考酚酸和足剂量环孢素治疗组相比，小剂量环孢素和依维莫司治疗组外周水肿、血脂障碍和高脂血症的发生率高出5%。

OK MDC live cell staining showed that the glioma cells to increase the role of everolimus in the acidic vesicle-like organelles ( from macrophage foam ) formation that everolimus can promote the formation of glioma cell autophagy .

行MDC活细胞染色显示，依维莫司作用于胶质瘤细胞增加了酸性囊泡样细胞器（自噬泡）的形成，可认为依维莫司可促进胶质瘤细胞自噬的形成。