demyelinating disease

Clinical Analysis on 51 Cases of Children with Demyelinating Disease

脱髓鞘疾病51例

Tumor - like demyelinating disease of the central nervous system

貌似肿瘤的中枢神经系统脱髓鞘病

Relapse Factors of Acute Central Nervous System Inflammatory Demyelinating Disease in Children

急性中枢神经系统炎性脱髓鞘病患儿复发的影响因素

Conclusions Most of optic neuritis was characterized as clinical inflammatory demyelinating disease .

结论大部分视神经炎患者具有炎性脱髓鞘疾病的临床特征；

CNS demyelinating disease in association with thymopeptide : 2 case reports

胸腺肽致中枢神经系统脱髓鞘病2例

Multiple sclerosis ( MS ) is a chronic inflammatory demyelinating disease of the human central nervous system .

多发性硬化是一种中枢神经系统慢性炎症性脱髓鞘疾病。

MRI of Tumor-Like Inflammatory Demyelinating Disease of Brain

脑肿瘤样炎性脱髓鞘病的MRI表现

The demyelinating disease of the central nervous system ( CNS ) is a disease which is often seen in youth .

中枢神经系统（centralnervoussystem，CNS）脱髓鞘性疾病是多发于青年人的神经系统常见病。

EAE is a T-cell-mediated demyelinating disease of CNS and a typical model of MS.

EAE是T细胞介导的CNS脱髓鞘疾病，是MS的经典动物模型。

Conclusion CNS inflammatory demyelinating disease could have some atypical representation on CT or MRI image , they were made easily the misdiagnosis .

结论中枢神经系统炎性脱髓鞘病CT或MRI可以有肿瘤样的非典型性表现，不易鉴别，容易造成误诊。

The side effects include injection site infusion reactions , infection , lymphoproliferative disease , demyelinating disease , and SLE-like syndromes .

TNF抑制剂的主要不良反应有注射部位反应、感染、肿瘤、淋巴增殖性疾病、神经脱髓鞘病变以及狼疮样综合征。

Background : Multiple sclerosis is a characterized demyelinating disease of the CNS and postulated to be a autoimmune disease .

研究背景多发性硬化一般被认为是以中枢神经系统炎性脱髓鞘疾病为特征的自身免疫性疾病。

Multiple sclerosis is an inflammatory demyelinating disease , and Wernicke 's encephalopathy is caused by deficiency of thiamine .

多发性硬化是一种以中枢神经系统炎性脱髓鞘为特征的慢性疾病，而Wernicke脑病是与物质代谢紊乱有关的疾病。

Background : Multiple sclerosis is a neurological demyelinating disease , which tends to attack the optic nerve , brain stem and spinal cord .

背景：多发性硬化症（MS）是一种中枢神经系统（CNS）脱髓鞘疾病，病变多发生在视神经、脑干和脊髓等部位。

Relapsing-remitting multiple sclerosis is an inflammatory demyelinating disease of the CNS that is presumed to have an autoimmune cause .

复发缓和多发性硬化是一种炎性中枢系统脱髓鞘疾病，推测由自身免疫引起。

For a long time , multiple sclerosis has been considered a primary demyelinating disease of the CNS extensive demyelination and axonal structure is relatively preserved .

长期以来一直认为MS是以CNS广泛的髓鞘脱失而轴索结构相对保存为特征的原发性脱髓鞘病变。

ADEM is a para or postinfectious autoimmune demyelinating disease of the central nervous system and has been considered a monophasic disease .

ADEM是一种中枢神经系统的感染后脱髓鞘性疾病，目前认为其病程是单相的。

Dendritic cell ( DC ) which act as the strongest antigen presenting cell ( APC ) in the body play an important role in demyelinating disease of CNS .

树突状细胞（Dendriticcell，DC）作为体内最强的抗原呈递细胞（Antigenpresentingcell，APC）在CNS脱髓鞘疾病中发挥着重要的作用。

Although the definite etiology and pathogenesis are not very clear up to now , many studies show that the immunological factors play a key role in the demyelinating disease of CNS .

虽然其确切的病因和发病机理尚不十分清楚，但许多研究表明免疫学因素在中枢神经系统炎性脱髓鞘病中起着关键性的作用。

The expression of Rho kinase , microglia and astrocyte is increased in EAE rats , They play an important role in the CNS inflammatory demyelinating disease .

EAE大鼠Rho激酶表达增加，胶质细胞反应明显，两者在中枢神经系统炎性脱髓鞘病中起到重要作用。

The common differential diagnosis of RPLS includes cerebral infarction ( especially top of the basilar artery syndrome ), demyelinating disease , encephalitis , venous sinus thrombosis . 6 .

RPLS需要与脑梗死（尤其是基底动脉尖综合征）、脱髓鞘疾病、脑炎及颅内静脉窦血栓形成等疾病鉴别。

Objective To investigate the clinical and imaging characteristics of tumor like inflammatory demyelinating disease of CNS , We have analyzed the reason of misdiagnosis , and summed up the main point of differential diagnosis .

目的探讨貌似肿瘤的中枢神经系统炎性脱髓鞘病的临床与影像学特点，分析误诊原因，并归纳诊断及鉴别诊断要点。

Results CNS inflammatory demyelinating disease could present edema and mass effect by CT or MRI , there was ring potentialization after enhancement , it was difficulty to distinguish from CNS demyelinating disease .

结果中枢神经系统炎性脱髓鞘病CT或MRI检查可以出现水肿及占位效应，增强后可以有环形强化，很难与中枢神经系统肿瘤相鉴别。

Conclusions ADEM was an inflammatory demyelinating disease of the CNS with multiple neurological signs , CSF and MRI examinations were helpful to establish the diagnosis , corticosteroid treatment was effective , its prognosis was good .

结论急性播散性脑脊髓炎是中枢神经系统常见的炎性脱髓鞘病变，神经系统临床表现多样，脑脊液、MRI检查有助于诊断，激素治疗有效，预后良好。

The pathogenesis of the demyelinating disease of CNS resembles other autoimmune disease whose process is relevant to autoantigens , activation of unspecific T cell and the inflammation reaction induced by T cell especially CD4 + T-helper cell one ( Th1 ) .

其发病机理与其它自身免疫性疾病相似，是自身抗原、非特异性T细胞活化和T细胞尤其是CD4~+T辅助细胞1（Thelpercell，Th）介导的炎症反应共同参与了脱髓鞘疾病的发病过程。