cyp2c19
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So gender , age and BMI may have no significant effect on genetic polymorphism of CYP2C19 .
可以初步推断,性别、年龄和体重指数可能不是CYP2C19遗传多态性的主要影响因素。
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Aim To assess the effect of gender on genetic polymorphism of cytochrome CYP2C19 in Chinese population .
目的考察性别对中国汉族人群细胞色素氧化酶CYP2C19遗传多态性的影响。
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People who have reduced functioning of their CYP2C19 liver enzyme cannot effectively convert Plavix to its active form .
体内肝酶CYP2C19机能丧失的人群不能有效地将波立维转化为其活性形式。
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Tests are available to assess CYP2C19 genotype to determine if a patient is a poor metabolizer .
目前可通过检测CYP2C19的基因来了解某人是否为代谢不良者。
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Conclusion We did not find the difference between the two CYP2C19 phenotypes in relation to the acid-suppressing effect of esomeprazole .
结论未观察到CYP2C19基因多态性对埃索美拉唑的抑酸效应的影响。
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Objective : To study the genotypical polymorphism of CYP2C19 , a cytochrome oxidase , in Chinese healthy and hyperthyroid populations .
目的:考察中国健康人群和甲亢患者细胞色素氧化酶CYP2C19遗传多态性的相关性。
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Cytochrome P450 2C19 ( CYP2C19 ) is an important hepatic microsomal enzyme . Its genetic polymorphism affects drug metabolism .
细胞色素P4502C19(CYP2C19)是一种重要的肝微粒体酶,它的遗传多态性影响着许多临床药物的氧化代谢。
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Plavix does not have its anti-platelet effects until it is metabolized into its active form by the liver enzyme , CYP2C19 .
波立维在被肝酶CYP2C19代谢转化为其活性形式前不具有抗血小板作用。
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Objective To investigate whether cytochrome P450 2C19 ( CYP2C19 ) / P450 2D6 ( CYP2D6 ) genetic polymorphisms were associated with schizophrenia in Chinese subjects .
目的探讨中国健康人群与精神分裂症患者细胞色素P4502C19(CYP2C19)/P4502D6(CYP2D6)遗传多态性的相关性。
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Background : Many studies have indicated that cytochrome P4502C19 ( CYP2C19 ) involved in the metabolism of proton pump inhibitors ( PPIs ), and it is the main metabolic pathway of omeprazole , lansoprazole and pantoprazole .
背景:研究表明细胞色素P4502C19(CYP2C19)参与质子泵抑制剂(PPIs)的代谢,是奥美拉唑、兰索拉唑和泮托拉唑的主要代谢途径。