cd7

The relationship between differentiation antigen CD7 and childhood acute lymphoblastic leukemia

分化抗原CD7与小儿急性淋巴细胞白血病的临床关系

Genotype and Cell Origin of Acute Leukemias Associated with Expression of CD7 Antigen

伴有CD7抗原表达的急性白血病的基因表型和细胞来源

Clinical significance of CD7 expression in associated with cytogenetics in acute myeloid leukaemia

急性髓细胞白血病表达CD7抗原的临床意义以及与细胞遗传学的相关性

Objective : To study the biological and clinical significance of CD7 + CD56 + AML .

目的：探讨CD7+CD56+急性髓系白血病（AML）的临床生物学意义。

CD7 is the extracellular ligand for human signal regulatory proteins , thus it causes negative regulatory effect ;

CD47是人抑制性受体信号调节蛋白（SIRP）的胞外配体，引发负性调节信号；

Expression of 5 Genes in CD7 Positive Acute Myeloid Leukemia Stem / Progenitor Cells from Bone Marrow

CD7阳性急性髓系白血病骨髓干/祖细胞5个基因表达的研究

CD7 Expression and its Significance in the Detection of Minimal Residual Disease in Adult Acute Myelocytic Leukemia

CD7在成人急性髓系白血病的表达及其在微小残留病检测中的应用

Chemotherapeutic effect of two different doses of cytarabine combined with anthracycline for CD7 positive acute myeloid leukemia

不同剂量阿糖胞苷的DA方案治疗CD7抗原阳性急性髓系白血病疗效分析

It is suggested that acute leukemias associated with CD7 antigen may be come from different early T cells and myeloid cells .

上述结果提示，伴有CD7抗原表达的急性白血病实际上是T、粒等多种细胞来源的白血病。

Objective To study the immunophenotype and P-glycoprotein expression in CD7 positive adult acute myeloid leukemia ( CD7 + AML ) .

目的研究CD7阳性急性髓系白血病（CD7+AML）的临床生物学特征。

Lymphoid-associated antigens expressed in 34.0 % of the AML patients , among which , CD7 expressed in 24.4 % of the AML patients .

34.0%的AML患者伴有淋系抗原表达，最常见为CD7（24.4%）。

Objective To report a case of acute myeloid leukemia ( AML ) with CD7 + near-tetraploid clones by doublet ( 8 ; 21 ) .

目的报道1例以CD7+和双重t（8；21）易位为特征的近四倍体克隆急性髓细胞性白血病（AML）。

Result : ① CD19 was the most commonly expressed of all B-lineage antigens detected , the positive rate was 100 % ; same as CD5 and CD7 for T-ALL .

结果：①B细胞系列的ALL（Ball）中CD19表达最常见（阳性率为100%），而T细胞系列的ALL（TALL）中CD5和CD7表达阳性率最高，均为90%；

In the MRD detection of CD7 ~ ( + ) AML , CD7 , combined with other myeloid markers , could effectively distinguish normal cells from leukemia cells in the dual-parameter dot plots .

在CD7+AML的MRD检测中，CD7与其他髓系抗原组合能够在双参数散点图上很好地区分白血病细胞与正常细胞。

CD7 was the most commonly expressed lymphoid antigen ( 20 . 2 % ), followed by CD19 ( 16 . 5 % ) and CD2 ( 15 % ) .

在淋系抗原中，CD7的表达最为常见（20.2%），其次是CD19（16.5%）和CD2（15%）。

The lymphoid antigen was positive in 57.7 % of cases , with the highest frequency of CD19 ( 36.6 % ) followed by CD7 ( 28.2 % ) . There was no CD20 expression among these patients .

57.7%的病例伴有淋系抗原表达，以CD19表达最常见（36.6%），其次为CD7（28.2%），未见CD20的表达。

The positive rate of the cell surface marker HLA-DR , CD38 and CD34 was high , 91 . 43 % . 85 . 19 % and 65 . 63 % respectively , and that of CD7 was 35 . 90 % .

结果：这两类白血病的HLA－DR、CD38、CD34阳性率很高，分别为91.43%，85.19%和65.63%，CD7阳性率为35.90%；

Conclusion : CD7 + CD56 + AML might constitute a distinct biologic and clinical disease entity . Our data showed that CD7 + CD56 + AML associated with less anemia , overexpression of PgP and CD34 and a high incidence of central nervous system involvement .

结论：CD7+CD56+AML具有独特的临床生物学特征，较少贫血，高表达PgP和CD34，常伴有中枢神经系统浸润。