calnexin

The assembly and transportation of HLA B27 molecule and its relationship with molecular chaperone calnexin and BiP

HLA-B27分子与分子伴侣的相关性研究

Conclusion The association of calnexin and BiP with B27 was mainly with nascent B27 molecules .

结论Calnexin及BiP均参与B27分子在细胞内的组装过程，主要与新生态的分子结合。

Calnexin / Calreticulin Cycle and Glycoprotein ER-Associated Degradation

Calnexin/Calreticulin循环与糖蛋白内质网相关性降解

Calnexin , an important lectin-like chaperone in endoplasm reticulum , can assist in protein fol - ( ding ) and modulate Ca ~ ( 2 + ) homeostasis in cell .

Calnexin是内质网中重要的类凝集素分子伴侣，其主要作用是辅助糖基化蛋白的折叠和装配，调节内质网中的Ca2+稳态平衡和Ca2+信号传导过程。

The accumulation of unfolded proteins in the endoplasmic reticulum ( ER ) lumen causes ER stress response , activates the unfolded protein response ( UPR ) signal pathway and consequently induces the expression of ER-located molecular chaperones ( such as BiP , calnexin , etc. ) in eukaryote cells .

真核细胞内质网中未折叠蛋白的积累会引起内质网胁迫（ERstress），激活未折叠蛋白应答（UPR）信号途径，从而诱导内质网中分子伴侣的表达（比如BiP和Calnexin等）。