brca

A positive BRCA test does not mean a leap to surgery .

仅仅是BRCA基因检测呈阳性，并不意味着你需要立即接受手术。

This does not affect normal cells because they can call on an alternative repair mechanism , controlled by their healthy BRCA genes .

这种治疗之所以不影响正常细胞，是因为它们能唤醒受健康BRCA基因组控制的备用修复机制。

Strains of CTV in a mixture of CTV infections can be separated by single BrCA transmission .

橘蚜对CTV具有分离株系的作用，通过单虫传播，可以将混合感染状态的CTV不同株系分离而获得纯化株系。

Bilateral prophylactic mastectomy or oophorectomy can reduce the incidence of breast cancer in BRCA mutation carriers .

单纯保乳术不适用于BRCA相关乳腺癌，应该考虑行双侧乳腺切除或保乳术联合双侧卵巢切除。

They found that 1 / 5 of the women had genetic flaws linked to breast cancer including the well known BRCA 1 and 2 genes .

他们发现，五分之一的女性都有与乳腺癌相关的基因缺陷，其中就包括著名的BRCA1和BRCA2基因。

Conclusion Contralateral breast cancer risk depends on age at first breast cancer and on the affected BRCA gene , and this risk should be considered in treatment planning .

结论：对侧乳腺癌的发病风险依赖与初诊乳腺癌的年龄和BRCA基因的变化，而且这种风险应该在治疗计划中得以考虑。

BRCA mutations cause about 5 to 10 percent of breast cancers and 10 to 15 percent of ovarian cancers among white women in the United States .

在美国的白人女性中，由BRCA基因突变导致的乳腺癌病例占5%-10%，卵巢癌病例占10%-15%。

But in tumours cells , where the BRCA pathway is disabled by genetic mutation , there is no alternative repair mechanism , and the cells die .

而在肿瘤细胞内，在基因突变使BRCA失去能力的地方，没有备选修复机制，细胞便死亡。

For BRCA genes , 94 % of non-Ashkenazi Jewish individuals and 19 % of those of Ashkenazi heritage had a mutation that would be missed .

携带有这两种基因突变的人一生中罹患肠癌的风险几乎是100%。对于BRCA基因，94%的非德系犹太人和19%的德系犹太人携带有可能被遗漏的基因突变。

BRCA genes take part in the harmed DNA mending process , maintain gene integrity and make the cell in which DNA has been damaged apoptosis , inhibit the pathogenesis and development of tumors .

BRCAs基因是抑癌基因，参与DNA损伤修复过程，保持基因组的完整性，促进DNA损伤细胞凋亡，抑制细胞癌变。

In my case , the Eastern and Western doctors I met agreed that surgery to remove my tubes and ovaries was the best option , because on top of the BRCA gene , three women in my family have died from cancer .

拿我的例子来说，中西医在诊断之后，都认为摘除卵巢和输卵管是我最好的选择，因为我不仅携带突变BRCA基因，还有三位女性亲人死于癌症。