The largest gains were seen by cosmetics companies Kao and Kose , food company Meiji , and three pharmaceutical companies : Shionogi & Co. , Chugai Pharmaceutical Co. , and Astellas .
最大的赢家包括花王和高丝化妆品公司、明治食品公司、以及盐野义制药株式会社、中外制药株式会社和安斯泰来制药厂三家制药公司。