UDCA

A Study on the Protective Effect of UDCA in the Model of Cholestatic Rats

熊去氧胆酸对实验性大鼠淤胆保护作用的研究

Transformation of CDCA in Poultry Bile into UDCA

鸡胆汁中鹅去氧胆酸转化为熊去氧胆酸的研究

Early application of UDCA therapy could significantly improve Child-Pugh classification .

早期应用UDCA治疗可明显改善Child-Pugh分级。

Conclusion : UDCA was a safe and effective drug in the treatment of ICP .

结论：UDCA是治疗ICP安全有效的药物。

The Clinical Observation and Interview on the Therapy with UDCA to the PBC Patients

PBC患者临床观察及UDCA治疗随访

UDCA was the most effective treatment of PBC .

UDCA是治疗PBC的最有效药物。

In addition to conventional postoperative care , control group received vitamin C , while UDCA was given to observation group .

除传统的胆肠吻合术后处理外，对照组于术后给予维生素C，而观察组则给予UDCA。

Conclusion Combination of SAMe and UDCA are safe , efficient , good treatment . The prognosis of pregnancy is improved .

结论SAMe联合UDCA是治疗ICP的安全有效的方法，可改善妊娠预后。

Ursodexcholis acid ( UDCA ), the primary chemical component of bear bile , has widely pharmacological value .

熊胆具有广泛的药理作用及应用价值。

There is currently no consensus on how to treat patients with a suboptimal biochemical response to UDCA .

目前，对UDCA应答欠佳患者的治疗方法尚不确定。

The expression of ER in low dose group dropped obviously in contrast with normal group and UDCA group ( P < 0.01 ) .

低剂量组ER的表达显著低于正常组和UDCA组（P<0.01）。

Compared the concentration of UDCA in aqueous humor and vitreous at 6h , P < 0.01 ;

给药6h后，房水和玻璃体内UDCA浓度相比较，P<0.01，差异具有显著性；

All 63 cases of patients to the UDCA treatment of Western medicine , Chinese medicine decoction of Chinese medicine by giving oral syndrome differentiation .

63例病人西医全部予UDCA治疗，中医通过辨证论治给予中药汤剂口服。

This article reviewed the advances in the study of UDCA for treating PBC , including mechanism , evidence of clinical effects and clinical applications .

本文就UDCA治疗PBC的作用机制、临床疗效依据、临床应用等方面的研究进展作一综述。

The choleretic action was both significant as treated with UDCA or lower dosage of Jin Shi San .

低剂量金石散和UDCA显示具有明显利胆作用。

The role of ursodeoxycholic acid ( UDCA ) and patient characteristics that predict the success of this tolerance are unclear .

熊去氧胆酸（UDCA）的作用以及能预测获得这种TIW后免疫耐受的患者特征尚不清楚。

The effect of Ursodeoxycholic acid ( UDCA ) combined with Domperidone in 156 patients with primary biliary reflux gastritis

熊去氧胆酸联合多潘立酮治疗原发性胆汁反流性胃炎156例临床研究

A Study on ~ 1H-NMR Characteristic Spectra of Epimer UDCA , CDCA and Determination of Bear Bile Powder

差向异构体熊去氧胆酸和鹅去氧胆酸的~1H&NMR谱学特征研究及熊胆粉主要成分测定

Objective To evaluate the efficacy and safety of ursodeoxycholic acid ( UDCA ) in the treatment of severe chronic hepatitis with cholestasis .

目的评价熊去氧胆酸（ursodeoxycholicacid，UDCA，商品名优思弗）治疗慢性肝炎重度伴胆汁淤积的疗效及安全性。

Our research is to observe the effect of combined application of two drugs , metformin and ursodeoxycholic acid ( UDCA ), in treatment of NAFLD .

本研究主要观察两种药物&二甲双胍及熊去氧胆酸联合疗法在非酒精性脂肪性肝病治疗中的作用。

ObjectiveTo investigate the effect of ursodeoxycholic acid ( UDCA ) on prevention of retrograde biliary tract infection after cholangioenterostomy .

目的：探讨熊去氧胆酸（UDCA）对胆肠吻合术后胆道逆行性感染的预防作用。

Ursodeoxycholic acid ( UDCA ) is the only safe and effective drug for the treatment of PBC proven by randomized controlled clinical trials .

熊去氧胆酸（UDCA）是惟一经随机对照临床试验证实的治疗PBC安全有效的药物。

Methods Totally 80 guinea pigs randomly divided into 4 groups i.e. blank group , lithogenic group , prevention by bear bile powder group and UDCA group .

方法将80只豚鼠随机分为4组，分别为空白组、致石组、熊胆粉预防组、熊去氧胆酸（UDCA）预防组。

There are many alternatives to bear bile on the market , containing the active constituent found in bear bile : UrsoDeoxyCholic Acid ( UDCA ) .

市场上有很多可以替代熊胆功能的药物，包括在熊胆上发现的有效成分：熊脱氧胆酸。

Objective To study the clinical therapeutic effectiveness on primary intrahepatic stones ( PIS ) treated by Ursodeoxycholic Acid ( UDCA ) combined with Xiaoyao San .

目的观察优思弗（熊去氧胆酸胶囊）联合逍遥散加味治疗原发性肝内胆管结石的临床疗效。

UDCA therapy not only decreases CSI ( cholesterol saturation index ) but also lowers APN activity in gallbladder bile of patients with cholesterol gallstones .

UDCA能够在降低胆固醇饱和指数的同时，也降低APN活性。

METHODS : 16 PBC patients were observed . Ursodeoxycholic Acid ( UDCA ) was used 13 to 15 mg / kg / day , with some Chinese herbal prescription .

方法：以16例PBC患者为观察对象，采用熊去氧胆酸（每日13-15mg/kg体重）和中药止痒方、软坚散、消黄散等中西医结合方法治疗。

By in vitro and in vivo experiments , the mechanism that UDCA protect the hepatocyte was proved mainly through the role of anti-apoptosis , but its exact mechanism was still unclear .

体内外实验证明，UDCA保护肝细胞损伤主要是通过抗凋亡作用，而其确切机制还不是很清楚。

UDCA is the U.S. FDA-approved treatment PBC only effective drugs , but UDCA could significantly prolong the survival period and the demand for liver transplantation there are different points of view .

熊去氧胆酸（UDCA）是美国食品和药品管理局（FDA）批准的治疗PBC的唯一有效药物，但UDCA能否可以显著延长病人生存期及对肝移植的需求尚有不同的观点。

It is estimated that 100,000 kg of synthesised UDCA is already being consumed each year in China , Japan and South Korea , and that the world consumption may be double this figure .

根据估计，每年大约有10万千克人工合成的熊脱氧胆酸在中国、日本和南韩售卖并使用。全球消费量可能是这个数目的双倍。