Thioguanine

A Simple and Rapid HPLC Method for Determination of 6 - Thioguanine Concentration in Human Leukemic Cells

一种简易检测人红细胞中6-硫鸟嘌呤浓度的HPLC法

Objective To establish a HPLC method to measure thioguanine nucleotides concentration in children with acute lymphoblastic leukemia .

目的：建立一种快速、灵敏、高效的方法，检测儿童急性淋巴细胞白血病红细胞中硫鸟嘌呤核苷酸浓度。

Simultaneous Determination of Trace of 2 , 6-Diaminopurine and Thioguanine by Synchronous Derivative Solid Substrate Room Temperature Phosphorimetry

同步扫描-导数-固体基质室温燐光法同时测定痕量2,6-二氨基嘌呤和硫鸟嘌呤的研究

Methods Mutant frequencies of somatic HPRT locus in peripheral blood lymphocytes of 30 healthy adults and 30 radiation workers were detected by using 6 thioguanine resistant ( TG r ) assay .

方法应用人外周血淋巴细胞抗6－TG分析技术检测了30例健康成人和30例放射工作者体细胞HPRT位点突变频率。

TAD ( thioguanine , cytosine arabinoside & daunorubicin ) regi - men was used in treatment of 12 cases aged from 17-47 of untreated ANLL .

采用TAD方案治疗急性非淋巴细胞性白血病（ANLL）12例，年龄17～47岁。

Objective To evaluate the activity and genotype of thiopurine methyltransferase ( TPMT ) and the concentration of thioguanine nucleotides ( TGNs ) as parameters for individualizing mercaptopurine ( 6-MP ) therapy .

目的探讨巯基嘌呤甲基转移酶（TPMT）活性、基因型和硫鸟嘌呤核苷酸（TGNs）浓度检测对6巯基嘌呤（6MP）化疗个体化的意义。