Protopine

Effect of protopine on rat blood pressure

普鲁托品对大鼠血压的影响

RP-HPLC method for determination of protopine in plasma and pharmacokinetics in rats

RP-HPLC法测定大鼠血浆的普鲁托品浓度及其药代动力学研究

Effects of protopine on tracheal smooth muscle and its mechanism

普罗托品松弛气管平滑肌的作用机制研究

A study on the structure of protopine acetate

原阿片碱盐酸盐的结构研究

Effect of protopine on rabbit platelet function

普罗托品对家兔血小板功能的影响

Aim The effects of protopine ( Pro ) on tracheal smooth muscle were observed .

目的观察普鲁托品（Protopine，Pro）对气管平滑肌的影响。

Effect of Protopine on Learning Ability and Acetylcholinesterase Activity of hippocampus and Cerebral Cortex in the Normal Rats

普洛托品对正常大鼠学习能力及海马、大脑皮层乙酰胆碱酯酶活性的影响

Influence of Different Vinegar Processing Method on the Contents of Tetrahydropalmatine and Protopine in Rhizoma Corydalis

不同醋制方法对延胡索中延胡索乙素和原阿片碱含量的影响

Effect of protopine on contraction and intracellular free calcium concentration of smooth muscle of thoracic aorta in rats

普罗托品对大鼠血管平滑肌收缩反应及细胞内游离钙浓度的影响

Distrubution and excretion of protopine in rats by RP-HPLC method

RP-HPLC法测普鲁托品在大鼠体内分布和排泄

Conclusions : Protopine can improve learning ability and decrease acetylcholinesterase activity of hippocampus and cerebral cortex in the normal rats .

结论：Pro可提高正常大鼠学习能力，并降低海马及大脑皮层乙酰胆碱酯酶活性。

Objectives : To investigate the pharmacological effect of protopine ( PRO ) on cardiovascular system and provide theoretical basis for treating cardiovascular diseases .

目的：探讨普托品（protopine，PRO）的心血管药理作用，为研制治疗心血管疾病新药提供理论基础。

RP-HPLC simultaneous determination of tetrahydropalmatine and protopine in Rhizoma Corydalis

RP-HPLC法同时测定延胡索药材中延胡索乙素和原阿片碱

Vasodilative mechanism of protopine in rabbit aorta

普鲁托品对家兔主动脉扩血管作用的机理

Objective To study the effect of protopine ( Pro ) on the intracellular free calcium ions of the smooth muscular cells of the thoracic aorta in rats .

目的探讨普罗托品（protopine，Pro）对大鼠血管平滑肌细胞内游离钙浓度的影响。

Effect of protopine on cytosolic Ca ~ ( 2 + ) in rabbit platelets EFFECT OF THROMBIN ON CYTOSOLIC CALCIUM AND MEMBRANE POTENTIAL IN SINGLE HUMAN PLATELETS

普鲁托品对兔血小板内钙的影响（英文）凝血酶对荧光标记的人单个血小板游离〔Ca~（2＋）〕和膜电位的动态影响

We have previously shown that the vasodilator effect of protopine ( Pro ) on rabbit aorta is related to the elevations of cAMP and cGMP .

本实验室先前的研究已证实，普罗托品（protopine，Pro）舒张家兔主动脉的作用，可能与其增加血管平滑肌细胞内cAMP和cGMP水平有关。

Objective To observe the effect of protopine ( Pro ) on blood pressure ( BP ) of the hypertensive and normal-tensive rats , to evaluate it 's potential availability in clinic .

目的观察比较普鲁托品对实验性高血压大鼠模型和正常大鼠血压的影响，评价其可利用性。

[ Objective ] To establish a method for simultaneous determination of protopine , berberine hydrochloride and tetrahydropalmatine in Yuanhuzhitong ( Rhizoma corydalis analgesic ) tablets .

[目的]建立同时测定元胡止痛片中原阿片碱、盐酸小檗碱、延胡索乙素含量的方法。

Methods : 28 days after protopine ( 0.5 mg / kg ) was administrated in the normal rats , learning ability was measured by using Y-maze , and acetylcholinesterase activity of hippocampus and cerebral cortex was determines .

方法：大鼠每天Pro0.5mg/kg灌胃，28d后三等分Y迷宫测定大鼠学习成绩，并测定海马及大脑皮层乙酰胆碱酯酶活性。