Heterodimer

By forming heterodimer with another bHLH . MRFs recognize and bind tO the E-box of DNA to activate the expression of muscle-specific genes .

MRFs通过与E蛋白家族的另一类bHLH形成异二聚体识别靶DNA上的E-box并结合，从而活化肌肉特异性蛋白的表达。

Initially , atRA activates a heterodimer RAR / RXR , which further recognizes and binds to retinoic acid receptor response element ( RARE ) consensus sequence , thereby activating or repressing target gene transcription .

AtRA可激活异二聚体RAR/RXR，后者通过识别和结合维甲酸受体反应元件（RARE），进而引起靶基因的转录激活或转录抑制。

Relationship between the level of Bax-Bcl-2 heterodimer and apoptosis of gastric cancer cells

Bax-Bcl-2异源二聚体与胃癌细胞凋亡的关系

Additionally , Siah-1S is found to interact with Siah-1 to form heterodimer or with itself to form homodimer .

另外我们发现Siah-1S不仅可以和Siah-1结合形成异源二聚体，也可以和自身形成同源二聚体。

The mating type genes in A loci encode two kinds of highly conserved homeodomain containing protein , which play important roles in A dependent development by the formation of protein heterodimer .

A位点的交配型基因编码两类含相似同源结构域的蛋白质，两种蛋白质形成异源二聚体，调节依赖A因子的发育过程；

These known sequenced mutations , either single base substitutions or small intragenic deletions ( 9-16bp ) were analyzed for peptide production , dimer formation and enzymatic activity of the heterodimer .

这些已知序列的突变体〔包括单碱基置换或基因内小段缺失（9～16个碱基）〕，用来分析肽的合成，二聚体的形成和杂工聚体酶活性〔1〕。

Conclusion Irradiation with both low dose and high dose of X-rays can induce the increase of the DNA binding activity of NF - κ B predominantly heterodimer p65 / 50 in peritoneal macrophages in irradiated mice .

结论：高、低剂量X射线诱导小鼠腹腔巨噬细胞转录因子NF-κB的DNA结合活性增强以异源二聚体p65/50增强为主。