ABC transporter

MDR-type ABC transporter proteins from medicinal plants were compared for the first time .

首次对药用植物MDR类ABC转运蛋白基因进行了比较研究。

Reconstruction of ABC Transporter Pathways of Archaea and Comparison of Their Genomes

古核生物ABC转运体系的重构及其基因组比较

This result further evidenced that the ABC transporter protein was related to the resistance of Streptococcus suis .

本研究结果进一步佐证了该ABC转运蛋白可能与细菌耐药性的产生相关。

Study of siRNA-directed RNA Interference of the Genes Related ABC Transporter in Silkworm , Bombyx mori

siRNA介导的家蚕ABC转运蛋白相关基因的干涉研究

SpsB gene encode ABC transporter substrate-binding protein and a signal peptide localized at N-terminal .

spsB基因编码ABC转运系统底物结合蛋白（ABCtransportersubstrate-bindingprotein），其N-端有一段18个氨基酸编码的信号肽序列。

Depending on the conserved amino acids of glycine betaine ABC transporter , a pair of degenerate primers were designed .

首先通过该转运系统ATP结合蛋白氨基酸的保守序列设计简并引物一对，获得约560bp的部分核苷酸序列。

The study of ABC transporter genes involved in the accumulation of Taxol requires the detailed acquaintance of the biosynthetic pathway of Taxol .

对紫杉醇累积相关ABC转运蛋白基因进行研究需要详细了解紫杉醇的生物合成途径。

ATP-binding cassette ( ABC ) transporter proteins constitute one of the largest protein superfamilies and are present in all organisms from bacteria to human . These proteins utilize the energy derived from ATP binding hydrolysis to drive substrate translocation across the membrane .

三磷酸腺苷结合盒转运蛋白（ATP-bindingCassette，ABC）广泛分布于从细菌到人类等各种生物体中，是最大的膜蛋白家族之一，它主要利用ATP水解释放能量实现多种底物的跨膜转运。

As a machine to efflux xenobiotics out of cells , ATP binding cassette ( ABC ) transporter protein has a major impact on the in vivo behavior of most of the drugs in use today , including drugs treating cancers , AIDS and infectious diseases .

作为异生物质排出细胞的通道，ABC转运蛋白对大多数现在使用的药物的体内行为产生重要影响，包括治疗肿瘤、艾滋病和微生物感染用药。

P-gp is a representative member of the superfamily of ABC transporters ( ATP-dependent transporter protein ), is considered to be dominant in the process to cause MDR .

P-gp是ABC转运蛋白（ATP-依赖性转运蛋白）超级家族中的一个代表性成员，被认为在引起MDR的过程中占主导地位。