罂粟碱

复方盐酸罂粟碱-甲磺酸酚妥拉明凝胶剂的HPLC测定

Determination of Compound Papaverine Hydrochloride and Phentolamine Mesylate Gel by HPLC

HPLC法检查注射用盐酸罂粟碱中的有关物质

Determination of Related Substances in Papaverine Hydrochloride for Injection by HPLC

方法：采用HPLC法测定野罂粟中野罂粟碱的含量。

Method : The content of nudicauline ⅰ is determined by HPLC .

HPLC法测定盐酸罂粟碱氯化钠注射液中盐酸罂粟碱的含量

Determination of Papaverine Hydrochloride in Papaverine Hydrochloride and Sodium Chlorde Injection by HPLC

去炎舒松组评分低于罂粟碱组和透明质酸酶组（p＜0.05），而罂粟碱组、透明质酸酶组之间无显著性差异（p＞0.05）。

Baker scales of the triamcinolone acetonide group was higher than that of the papaverine group and hyaluronidase group ( p < 0.05 ) .

目的：建立注射用盐酸罂粟碱中盐酸罂粟碱的HPLC含量测定方法。

Objective : To establish a HPLC method for determination the content of papaverine hydrochloride for injection .

目的考察野罂粟全草中野罂粟碱最佳提取方法以及确定HPLC含量测定方法学。

Objective To investigate the best extractive method of papaverine from whole wild poppy and determine the assay methodology of HPLC .

血管内皮细胞Fc？罂粟碱损伤血管内皮。

Papaverine do damage to endothelial cells .

结论在颅内动脉瘤夹闭术中，罂粟碱浸泡术野可增加rCBF；

Conclusion Local application of papaverine can increase rCBF during intracranial aneurysm surgery .

研制了以中性载体冠醚A1为电活性物的涂碳罂粟碱敏感膜电极。

The neutral carrier membrane electrode of papaverine was developed for the quantitative determination of papaverine in Chafing dish .

1Baker评分对照组（生理盐水组）分值明显高于各实验组（去炎舒松组、罂粟碱组、透明质酸酶组）（p＜0.01）。

Capsular firmness : ( 1 ) Baker scales : Baker scales of the control group ( saline groups ) were evidently higher than that of the three experiment groups ( triamcinolone acetonide groups , papaverine groups and hyaluronidase groups ) ( p < 0.01 ) .

目的观察在控制性降压下的颅内动脉瘤夹闭术中罂粟碱浸泡术野对局部脑血流（rCBF）的影响。

Objective To observe the effects of local application of papaverine on regional cerebral blood flow ( rCBF ) in patients undergoing intracranial aneurysm surgery .

结论野罂粟全草中野罂粟碱用pH4酸水提取得率较高。

Conclusion Papaverine extracted from whole wild poppy by PH4 acid water has a higher extractive rate .

应用罂粟碱后，2组rCBF均明显升高（P<0.05），其中A组增加的幅度明显大于B组（P<0.05）。

After local application of papaverine , rCBF significantly increased in both groups ( P < 0.05 ), but the degree of increasing in group A was higher than that in group B ( P < 0.05 ) .

为了探讨测量冠状动脉血流储备（CFR）的可靠性方法，本研究在23例心脏病组（A组）和11例正常组（B组）中应用冠脉内注射罂粟碱测量了CFR。

In order to explore the reliable method for measurement of coronary flow reserve ( CFR ), 23 patients with heart diseases ( group A ) and 11 normal subjects ( group B ) were studied by intracoronary Papaverine .

在11例正常人和20例冠状动脉狭窄（≥50%）患者中，采用冠状动脉内多普勒超声血流钢丝和冠脉内注射罂粟碱测量冠状动脉血流储备（CFR）。

To study the validation of Doppler guidewire with intracoronary papaverine for assessment of coronary flow reserve ( CFR ), 11 normal subjects ( N ) and 20 patients with coronary artery disease ( C ) were studied .

目的：探讨常温下尼可地尔（nicorandil，NCR）和罂粟碱对大隐静脉血管桥血管内皮超极化因子（endothelium-derivedhyperpolarizingfactor，ED-HF）介导血管舒张功能的影响。

AIM : To explore the protective effect of nicorandil ( NCR ) and papaverine on saphenous vein graft ( SVG ) endothelium derived hyperpolarizing factor ( EDHF ) mediated vasodilatation under normal temperature . METHODS : The organ chamber technique was used .

方法应用经皮血管成形术（PTA）和超选择动脉内灌注罂粟碱（IAP）治疗5例动脉瘤夹闭术后SCVS病人。

Methods Five patients with subarachnoid hemorrhage were reported , in which aneurysms had been clipped and super-selective intra-arterial infusion of papaverine ( IAP ) and percutaneous transluminal angioplasty ( PTA ) were employed for the treatment of symptomatic cerebral vasospasm .

从喜树（CamptothecaacuminataDecne）的根、枝条、叶和果实中分离纯化了48株内生真菌，其中菌株J-3、J-4J、-5、J-8对盐酸罂粟碱、硫酸长春碱等天然活性产物具有转化能力。

48 strains of endophytic fungi were isolated from the roots , branches , leaves and fruits of Camptotheca acuminata Decne , among which strains J-3 、 J-4 、 J5 、 J-8 could modify the structures of papaverine and vinblastine .

罂粟碱对臂丛神经阻滞作用的临床研究

Clinical study of the influence of papaverine on brachial plexus block

扩张器囊壁对罂粟碱渗透性的体外实验研究

The vitro model study on the diffusion of papaverine to expander membranes

外用罂粟碱霜加速组织扩张的实验研究

Experimental study on enhancement of tissue expansion with papaverine cream

内皮细胞的功能可影响罂粟碱和利多卡因的血管舒张作用。

The endothelium influenced vasodilation effect of papaverine and lidocaine .

罂粟碱明胶微球对脑血管痉挛的治疗作用

Efficacy of papaverine-gelatin microspheres treatment on vasospasm following subarachnoid hemorrhage in vivo

罂粟碱是辅助组织扩张的有效药物之一。

Papaverine is one of the drugs that can enhance tissue expansion .

罂粟碱加热盐水膀胱灌注治疗女性尿道综合征

Intravesical instillation of papaverine and hot water to treat female urethral syndrome

结果：罂粟碱透皮累积释药量与时间呈线性关系。

RESULTS The cumulative penetration amount of papaverine was linear related to time .

结果：盐酸罂粟碱氯化钠注射液对细菌内毒素检查无干扰作用。

RESULTS : The injection will not interfere to the bacterial endotoxins test .

基于中性载体的罂粟碱敏感膜电极的研制

Study on the neutral carrier membrane electrode of papaverine

罂粟碱加速组织扩张的生物力学研究

Biomechanical study of tissue expansion accelerated by papaverine cream