泮托拉唑钠

溶液pH值低于7.0时泮托拉唑钠极不稳定；

It was extremely unstable when pH value of pantoprazole sodium solution was lower than 7.0 ;

HPLC法测定泮托拉唑钠肠溶片的含量

Determination of Pantoprazole Sodium Enteric-Coated Tablets by HPLC

泮托拉唑钠及胶囊的HPLC测定

Determination of Pantoprazole Sodium and Its Capsules by HPLC

方法用HPLC法测定配伍后的泮托拉唑钠含量变化，同时观察其外观及pH值的变化。

Methods The change in content was determined by HPLC , and the change in appearance and pH was inspected .

RP-HPLC梯度洗脱法测定泮托拉唑钠的有关物质及含量

RP-HPLC gradient elution analysis for the determination of pantoprazole soldium and its related substances

结论泮托拉唑钠大鼠长期毒性试验无毒反应剂量为2g·kg-1。

Conclusion The no-toxic-effect does of Pantoprazole Sodium is 2g · kg ~ - 1 .

结果泮托拉唑钠与09%NS配伍，3h内较稳定，其余方法配伍均不稳定。

Results The compatible admixture of pantoprazole sodium for injection with NS is stability of all others for the compatible admixture .

结果：注射用泮托拉唑钠在4种常用输液以及钾、镁、钙离子水溶液中于4h内其含量、外观、pH值、最大紫外吸收波长均无明显改变。

RESULTS : No obvious changes were noted in terms of contents , appearances , pH value , UV - absorption maximum wavelength for the injectable pantoprazole sodium solution within 4 hours either in 4 kinds of common infusions or in potassium , magnesium , calcium ions water solutions .

泮托拉唑钠肠溶微丸胶囊人体相对生物利用度和生物等效性研究

Relative bioavailability of sodium pantoprazole enteric-coated micro-pill capsule in human subjects

复方泮托拉唑钠胃内漂浮片的制备及含量测定

Preparation and Quality Control of Compound Pantoprazole Sodium Gastric Retention Tablets

泮托拉唑钠在果糖氯化钠注射液中的稳定性

The stability of pantoprazole sodium in fructose and sodium chloride injection

目的：研究泮托拉唑钠的合成方法。

OBJECTIVE : To study on the synthesis of pantoprazole sodium .

泮托拉唑钠治疗急性上消化道出血21例

Clinical Evaluation of Pantoprazole in the Treatment of Acute Upper Gastrointestinal Hemorrhage

泮托拉唑钠肠溶胶囊处方工艺及稳定性研究

Study on Preparation and Stability of Pantoprazole Sodium Enteric-Coated Capsules

泮托拉唑钠大鼠长期毒性研究

Study on long-term toxicity of Pantoprazole Sodium in rats

注射用泮托拉唑钠与3种常用注射液的配伍稳定性考察

Study on the Stability of Compatible of Pantoprazole Injection and Three Injection Solutions

目的：制备泮托拉唑钠冻干针剂。

OBJECTIVE : To investigate the preparation technic of pantoprazole sodium freeze-dried injection .

目的评价2种泮托拉唑钠肠溶片（抗溃疡药）的生物等效性。

Objective To evaluate bioequivalence of pantoprazole sodium enteric-coated tablets in healthy volunteers .

泮托拉唑钠冻干注射剂的研制

Preparation of Pantoprazole Sodium Freeze - dried Injection

注射用泮托拉唑钠的稳定性考察

Study on the Stability of Injectable Pantoprazole Sodium

结论：泮托拉唑钠肠溶片两种制剂具有生物等效性。

[ WTHZ ] CONCLUSION : The two preparations of pantoprazole sodium are bioequivalent .

前言：目的：研究泮托拉唑钠肠溶胶囊工艺处方。

Objective : To optimize the formulation and preparation of Pantoprazole Sodium Enteric-Coated Capsules .

泮托拉唑钠临床常用剂量对大鼠急性反流性食管炎动物模型的影响

Effects of Therapeutic Dose of Pantoprazole Sodium on Rat Animal Model with Acute Reflux Esophagitis

泮托拉唑钠抗胃溃疡药理研究

Study on Antiulcerative Effect of Pantoprazole Sodium

目的考察注射用泮托拉唑钠与不同输液的配伍稳定性。

Aim To study the compatibility of pantoprazole sodium for injection with four kinds of infusion solutions .

结论：所选路线简便易行，是合成泮托拉唑钠的较好方法。

CONCLUSION : It is a better way to prepare pantoprazole sodium with a relative high yield .

泮托拉唑钠的合成研究

Synthesis of pantoprazole sodium

泮托拉唑钠组无不良反应，雷尼替丁组有1例出现恶心症状，不良反应发生率为2.85%。

The rates of side effects were 0 % in Pantoprazole group and 2.85 % in Ranitidine group .

目的：验证与评估诺森（注射用泮托拉唑钠）治疗上消化道出血的临床疗效和安全性。

OBJECTIVE : To verify and evaluate the effect and safety of pantoprazole in treating hemorrhage of upper digestive tract .

结论：该法为泮托拉唑钠的微生物限度检查提供了依据，对药品的生产及检验部门有实用的价值。

Conclusion : The results are credible and accurate , the method has useful value to the manufacturer and identifier of drugs .