曼氏血吸虫

曼氏血吸虫发育过程中的基因组DNA变异

Genomic variability between adult and cercaria of Schistosoma mansoni

与用曼氏血吸虫IHA和ELISA法检测结果相同。

The results were the same as with IHA and ELISA of Schistosoma mansoni .

该cDNA序列与曼氏血吸虫肌动蛋白轻链基因高度同源，核苷酸水平的同源性为84%；氨基酸水平的同源性为86%；

And this cDNA sequence was highly homologous to the known dynein light chain genes of S.mansoni with the identity in nucleotide sequences of 84 % and the identity in amino acid sequences of 86 % .

结论用EST策略筛选到一个日本血吸虫新基因，编码eIF2α亚基，全长编码序列与曼氏血吸虫eIF2α亚基mRNA高度同源。

Conclusion The novel gene found by EST strategy may encode a eIF2 α which is highly homologous to Schistosoma mansoni eukaryotic eIF2 α mRNA .

科学家将化合物直接对TGR酶、带有血吸虫病的蠕虫及感染曼氏血吸虫的老鼠身上进行实验。

They tested the compounds on the TGR enzyme itself , the worms that carry schistosome parasites , and mice infected with Schistosoma masoni .

曼氏血吸虫中间宿主&藁杆双脐螺Biomphalariastraminea（Dunker）在我国的发现

The discovery of Biomphalaria straminea ( dunker ), an intermediate host of Schistosoma mansoni , from China

根据日本血吸虫原肌球蛋白cDNA序列和曼氏血吸虫的原肌球蛋白cDNA序列M27512的保守区设计引物，采用RT-PCR方法，成功克隆了土耳其东毕吸虫的原肌球蛋白全长cDNA序列。

According to the tropomyosin ( TM ) cDNA 's keeping sequence of Schistosoma japonicum ( L76203 ) and Schistosoma mansoni ( M27512 ), a pair of primer were designed and used to RT-PCR . The TM full-length cDNA sequence of the Orientobilharzia turkestanicum were successfully cloned by RT-PCR .

结论蒿甲醚对小鼠曼氏血吸虫21d童虫的最低有效剂量为200mg/kg，可引起曼氏血吸虫成虫萎缩、退化或死亡。

Conclusion The minimum effective dosage of artemether against 21 d old S.mansoni in mice is 200 mg / kg . Artemether also exhibits effect against adult schistosomes , including shrinkage and degeneration , and can lead to worm death .

放射致弱曼氏血吸虫尾蚴对小鼠血清抗体的影响

Effects of Radiation-attenuated Schistosoma mansoni Cercariae on Serum Antibodies in Mice

曼氏血吸虫卵可溶性抗原基因克隆的研究

Gene cloning of a soluble egg antigen of Schistosoma mansoni

曼氏血吸虫成虫确定抗原的研究

Studies on Defined Antigen of Adult Worm of Schistosoma mansoni

蒿甲醚和青蒿琥酯对感染曼氏血吸虫小鼠治疗作用的初步研究

Therapeutic effect of artemether and artesunate in mice infected with Schistosoma mansoni

抗曼氏血吸虫童虫单克隆抗体的制备

Preparation of Monoclonal Antibodies Against Schistosomulum of Schistosoma mansoni

实验室研究已经证实了曼氏血吸虫在吡喹酮药物压力下可产生抗药性。

Studies confirm that schistosoma mansoni can produce drugresistance to praziquantel in laboratory .

提示日本血吸虫嘌呤补救合成代谢途径与曼氏血吸虫有差异。

The purine salvage pathway of S.japonicum may be different with that of S.mansoni .

环孢素A体外抗曼氏血吸虫幼虫的电镜学研究

Electron microscopic study on effect of cyclosporin A against larval Schistosoma mansoni in vitro

曼氏血吸虫脊髓病：临床和病理表现

Schistosoma mansoni myelopathy : Clinical and pathologic findings

曼氏血吸虫感染鼠肝脏虫卵肉芽肿反应及胶原含量定量测定

Quantitative detection on granuloma and collagen contents in livers of mice infected with Schistosoma mansoni

蒿甲醚引起小鼠体内日本血吸虫和曼氏血吸虫皮层变化

Tegument changes of Schistosoma japonicum and Schistosoma

干扰素在体外对模拟的曼氏血吸虫虫卵肉芽肿的抑制作用

In vitro inhibitory effect of interferon on simulated granuloma formation by eggs of Schistosoma mansoni

本研究结果也说明，曼氏血吸虫成虫21KDa可溶性抗原为曼氏血吸虫成虫的表面抗原。

The results indicate that 21 KDa soluble antigen of adult worm of S.mansoni is a surface antigen .

日本血吸虫和曼氏血吸虫成虫31/32kD蛋白的纯化及在诊断中的应用

Purification of 31 / 32kd proteins of adult Schistosoma japonicum and Schistosoma mansoni and application in diagnosis of schistosomiasis in ELISA

[结论]环孢素A具有直接抗曼氏血吸虫的作用，合胞体受损是药物作用的主要机制。

[ Conclusion ] The antischistosomal action of CsA is direct , the syncytium is the main site for CsA attack .

这个技术开辟了全基因组范围内和在个别位点层次上分析曼氏血吸虫表观遗传机制的新方法。

This technique opens new ways for analyzing epigenetic mechanisms in S.mansoni at a whole-genome scale and on the level of individual loci .

目的：通过观察青蒿琥酯对曼氏血吸虫雌虫产卵的影响，分析药物的抗生殖作用。

Aim : To study the anti-fecundity effect of artesunate against the schistosoma mansoni by observation and analysis of the parasite egg laying .

但是吡喹酮又不能避免重复感染，而且近年来曼氏血吸虫已经有吡喹酮抗性虫株的报道，耐药虫株的出现引起了人们的不安与高度关注。

However , chemotherapy does not prevent re-infection , and some isolates of Schistosoma mansoni ( S. mansoni ) that are resistant to high doses of praziquantel have been found in Egypt .

结论鼠体内吡喹酮的治疗对曼氏血吸虫吡喹酮敏感株和抗性株肝脏虫卵肉芽肿的形成影响作用具有显著差异；

Conclusion There were significant differences in the effect of praziquantel on the formation of egg-granulomas in the livers of Schistosoma mansoni worms between praziquantel-resistant and - susceptible parasite isolates in vivo .

研究人员用恒河猴进行实验，用曼氏血吸虫寄生造成其中一些猴子急性感染，另外一些未受感染正常而健康。

The researchers conducted experiments with rhesus monkeys , some of which had an acute infection with the Schistosoma mansoni parasitic worm and some of which were parasite-free , normal and healthy .

目的应用感染曼氏血吸虫（利比里亚株）的小鼠观察蒿甲醚单剂量与效应的关系，虫体肝移及蒿甲醚所引起的虫的形态学和组织病理学变化。

Objective To investigate the effects of artemether on Schistosoma mansoni harboured in mice , with particular consideration on single dose-efficacy relationship , hepatic shift and artemether-induced alterations in worm morphology and histopathology .

对曼氏血吸虫慢性感染的研究已经开始涉及CD4~+CD25~+调节性T细胞的免疫调节作用，但迄今为止，在日本血吸虫感染的研究中尚无有关报道。4种引起慢性感染的肝炎相关病毒的流行病学研究

Recently , growing evidences have been presented to support the association between the chronic infections and CD4 + CD25 + regulatory T cells . Epidemiological study on four hepatitis related viruses associated with chronic infections