抗癌基因
- 名antioncogene
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首乌对老年小鼠脾组织中抗癌基因P(53)表达的影响
Effect of Radix Polygoni Multiflori on antioncogene p_53 expression in spleen of senile rat
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乳腺癌中癌基因抗癌基因表达分析
Analysis of the Expression of Oncogene and Antioncogene in Breast Cancer
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乳腺癌中抗癌基因P(53)的突变与临床意义
Mutations of antioncogens P_ ( 53 ) and its clinical significances in breast cancer
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抗癌基因P53蛋白在肺癌中的表达
Expression of anti - oncogenetic protein P53 in human lung cancer
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p53抗癌基因在能量限制大鼠胰腺泡细胞的表达特性
Characterization of the expression of p53 tumor suppressor gene in
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常见肿瘤中抗癌基因P53异常的研究
Detection of P53 Gene Abnormalities in Human Tumors
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肺鳞癌抗癌基因P53突变与人孔头状瘤病毒感染的分析
Association between mutation of p53 gene and human papillomavirus infection in squamous cell carcinoma of the lung
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人胰腺腺癌中抗癌基因P53的突变
P53 mutations in pancreatic adenocarcinoma
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人胃癌细胞株Rb抗癌基因缺失的研究
Deletion of Rb gene in human gastric cancer cell lines
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目的为揭示P53抗癌基因与卵巢上皮肿瘤发病学的关系,对P53基因5-8外显子突变进行了检测。
Objective To evaluate whether P53 gene mutation was related with the pathogenesis of ovarian malignant epithelial tumors or not .
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抗癌基因Rb在肾癌和膀胱癌中的表达及其与组织病理的关系
Expression of tumor suppressor gene Rb at different pathological grade in bladder and renal cell carcinoma
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口腔癌及癌前病变中C-myc癌基因与Rb抗癌基因表达的意义
Significance of expression of c-myc oncogene and retinoblastoma gene in oral squamous cell carcinoma and premalignant lesions
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本结果提示人睾丸精原细胞瘤的发生与抗癌基因Rb蛋白产物表达的缺失和P(53)基因的突变有关。
The results are suggest that inactivation of Rb gene and mutation in P_ ( 53 ) gene associated with the development of human testicular seminoma .
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p53基因是一种抗癌基因,其主要功能是抑制细胞增殖、诱导细胞凋亡和诱导分化。
The p53 gene is a kind of tumor suppressor gene . Its main function is inhibiting cell proliferation , inducing apoptosis and leading to the cell differentiation .
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目的研究肝细胞癌p53和Rb基因的突变特点和规律。探讨2种抗癌基因在肝癌发生过程中的作用及其与组织学和预后的关系。
Objective To explore the characteristics and regular patterns of the anticancer gene p53 and Rb mutations in hepatocellular carcinoma ( HCC ) and its significance .
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Rb抗癌基因在口腔癌、白斑、扁平苔藓中表达的阳性率分别为30%、0和7%。
The Rb gene protein was detected in 30 % , 0 and 7 % of the oral SCC , leukoplakia and lichen planus , respectively .
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一些抗癌基因的失活来源于其3′UTR的结构变化;
That the inactivation of some antioncogenes came from the structural changes of their 3 ′ UTR ;
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Rb基因是一种抗癌基因,其产物Rb蛋白与细胞转化、细胞周期调节及转录调控有密切关系。
Rb gene is a cancer suppressor gene . Its product , Rb protein has close relation with the regulation of cell transformation , cell cycle and transcription .
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结论:内镜Nd:YAG激光是治疗食管和贲门早期表浅癌的有效方法。抗癌基因p53和DNA倍体数与病人的预后有关。
Conclusions : Endoscopic Nd : YAG laser was a safe and effective therapy for early carcinoma of the esophagus and the gastric cardia , and p53 protein and DNA ploid would be valuable for predicting the prognosis .
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而AOH诱导24h,1周和3周的胎儿食管上皮未发现抗癌基因Rb的丢失;
There were not any deletion of Rb gene in HFE treated with AOH for 24 hours in the first week and the third week .
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目的:研究癌基因(ras,cMyc)及抗癌基因(p53)蛋白在喉癌及癌旁不同距离处的复合表达及意义。
Aim : To study the co expression and its significance of oncogene ( ras and c myc ) and anti oncogene ( p53 ) in laryngeal carcinoma and mucosa within different distances of carcinoma .
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目前已经发现,3′UTR参与一些已知的癌基因和抗癌基因的功能调控;
It has been found that the 3 ′ UTR is involved in regulation of function of known oncogenes and antioncogenes ;
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为研究石棉致癌的分子机理,本研究首次直接分析石蜡包埋的石棉肺癌病例肺组织中抗癌基因p53的突变情况。
To explore the carcinogenic effect of asbestos at molecular level , we directly analyzed the mutations of exon 5,7 and 8 of anti oncogene p53 in paraffin embedded human lung tissue affected by asbestos for the first time .
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Schatzlein及其同事将抗癌基因包装成非常小的纳米微粒仅被癌细胞摄取,而正常细胞不受影响。
Schatzlein and colleagues packaged anti-cancer genes in very small particles that are only taken up by cancer cells , leaving healthy cells unharmed .
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结论:AOH激活了EGFr癌基因,EGFr癌基因的激活可能是食管上皮癌变的启动性变化,Rb抗癌基因的丢失在AOH诱导的食管癌发生中可能是一种较晚期的改变。
Conclusion : AOH could activate EGFr . The activation of EGFr gene is probably the initiated change in the canceration course of esophageal epithelium , and the inactivation of Rb anti oncogene might be involved as late event in esophageal carcinogenesis .
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人体既有原癌症基因,又有抗癌基因。
Both the human proto-oncogene , another anti-cancer gene .
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203例肺癌癌基因与抗癌基因癌蛋白的研究
Studies on oncoprotein of oncogene and anti-oncogene in 203 cases of lung cancer
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抗癌基因P~(53)蛋白在肺癌组织中的异常表达及意义
Clinical significance of p ~ ( 53 ) protein abnormal expression in lung cancer
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用可调控靶向无肠腺病毒载体携带抗癌基因治疗恶性肿瘤的研究
Construction of Regulatable Cancer Targeted Gutless Adenovirus Vector Carrying Anticancer Gene to Treat Malignant Tumor
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本文观察了12例男性乳腺癌的癌基因与抗癌基因产物的表达。
Expression of oncogene and anti-oncogene products in 12 cases of male breast carcinoma was studied .