多肽疫苗

FSHRB细胞表位筛选及其多肽疫苗抗生育作用的研究

Identification of B-cell Epitope of FSHR and Study on Antifertility Effect of Its Polypeptide Vaccine

抗A5型口蹄疫病毒重组多肽疫苗的研究

Study on the Recombinant Polypeptide Vaccine against Foot-and-mouth Disease Virus Type A5

多肽疫苗CopI诱导的特异性免疫反应

Study on peptide vaccine Cop-I induces the specific immune response in MS patients

DNA疫苗是继减毒疫苗、灭活疫苗、亚单位疫苗和重组多肽疫苗之后的又一新型疫苗，比其它疫苗高效、安全且易于大量生产。

DNA vaccine is a new vaccine after live attenuated , whole killed , subunit and recombinant one , etc. It 's better than them at efficiency , safety and ease to produce .

目的找出人巨细胞病毒（HCMV）单克隆抗体识别的抗原表位以进行HCMV多肽疫苗的研制。

Objectives To define the epitopes of HCMV with McAb aiming at preparing peptide vaccine in future .

基于CTL表位的宫颈癌治疗性多肽疫苗的分子设计、合成及免疫学效应研究

Molecular Design and Synthesis and Immunological Effect of Therapeutic Peptide Vaccine Against Cervical Cancer Based on Immunodominant Epitope

目前，最常见的新型FMD疫苗是生物合成多肽疫苗。

At present , the most frequently used new-type FMD vaccine is polypeptide vaccine .

本研究主要包括研制大肠杆菌、酵母表达的A、O型FMDV双价多肽疫苗；制备A、O型FMDV双价DNA疫苗及如何提高DNA疫苗的免疫效果等内容。

This research focused on the development of bivalent vaccine against FMDV using prokaryotic and yeast expression system , the development of bivalent DNA vaccine and improvement of the efficacy of FMDV DNA vaccine .

目的：研究人工合成葡糖基转移酶GTF第552～570位的多肽疫苗HDS的免疫原性。

Objective : To investigate the antigenicity of the peptide vaccine HDS ( 552 ~ 570 ) from Streptococcus mutans glucosyltransferase ( GTF ) .

结果经修饰的HER-2/neu多肽疫苗可促进T细胞增殖，促进T细胞分泌IFN-γ及CTL杀伤乳腺癌细胞。

Results Modified HER-2 / neu peptide vaccine could promote T cells proliferation , the incremental secretion of IFN - γ by T cells and the activation of killing breast cancer cells of CTLs .

汉滩病毒核蛋白CTL表位的有效预测，大幅度减少了合成候选9肽的数量，降低了成本。为肾综合征出血热细胞免疫应答的研究以及多肽疫苗的设计，奠定了重要基础。

The effective epitope prediction can significantly cut down the numbers and the costs of candidate 9-mer peptide synthesized , and provide a means to study the cellular immune response and design polypeptide vaccine in patients with HFRS .

高特异性HER2/neu手性多肽疫苗实验研究

Experimental Studies on Highly Specific HER2 / neu Chiral Peptide Vaccine

合成多肽疫苗研究进展含硅重键化合物

Progress in Synthetic Peptide Vaccine Compounds with Sillcon Multipe Bond

然而，多肽疫苗的发展面临巨大挑战。

However , development of peptide-based vaccine faces significant challenges .

宫颈癌治疗性多肽疫苗的分子设计及免疫学功能研究

Molecular design and immunologic effect of therapeutic peptide vaccine against cervical cancer

血吸虫病多肽疫苗的设计与合成研究

Studies on Design and Synthesis of Peptide Vaccines Against Schistosomiasis

肿瘤治疗性多肽疫苗&重组人纽表位肽12质控方法的研究

Study on methods for quality control of recombinant human neu epitope peptide 12

四价重组A群链球菌多肽疫苗基因序列的合成及克隆

Synthesis and Cloning of Gene Sequence of Tetravalent Recombinant Group A Streptococcal Polypeptide Vaccine

合成多肽疫苗研究进展

Progress in Synthetic Peptide Vaccine

但由于多肽疫苗的免疫原性较差，只能诱导短期的、较低水平的体液免疫反应。

However , peptides with B epitopes as compared to proteins are less immunogenic and often lead to induce short term and reduced humoral responses .

因而探讨某种新的疫苗分子和兔疫方式很有必要。合成多肽疫苗是一个较为理想的选择。

Therefore , it was essential to explore new molecular targets and new types of vaccine , and synthesized polypeptide was one of the ideal alternatives .

单克隆抗体和多肽疫苗与白血病相关抗原为治愈急性白血病带来了希望。

Monoclonal antibodies and peptide vaccination with leukemia-associated antigens also brought the hopes of increasing the remission and cure rates for patients with acute myeloid leukemia .

肿瘤疫苗包括多肽疫苗、基因疫苗、重组病毒疫苗、肿瘤细胞疫苗、多肽冲击的树突细胞疫苗等。

Currently , a range of cancer vaccine strategies are being tested including those using peptides , DNA / RNA , viral vectors , tumor cells , pulsed dendritic cells etc.

子宫颈癌疫苗包括以人乳头瘤病毒为基础的多肽疫苗、载体疫苗、融合蛋白疫苗和嵌合疫苗及树突状细胞疫苗等治疗性疫苗和人乳头瘤病毒预防性疫苗。

The therapeutic vaccines based on human papillomavirus ( HPV ) of cervical cancer are mostly summarized , including polypeptides vaccine , carrier vaccine , fusion protein or chimeric vaccine , and DC vaccine .

血吸虫病在世界范围内严重危害人类健康其免疫控制的重要策略之一是研制有效的合成多肽疫苗。

Developing an effective synthetic peptide vaccine is an important strategy for the immunological control of schistosomiasis which is one of the major parasitic diseases seriously affecting human health in the world , especially in the developing countries .

葡糖基转移酶多肽偶联疫苗抗原性

The antigenicity of peptide vaccine HDS from Streptococcus mutans glucosyltransferase

这项技术已经在医用活性多肽以及疫苗的研制、功能基因的鉴定、植物体内生物合成途径的研究等方面发挥越来越重要的作用。

It has played an important role in study production of pharmaceutical active peptides and vaccines , examination of gene function and studies of plant biosynthetic pathways etc.

联用抗口蹄疫病毒重组多肽及DNA疫苗诱发豚鼠产生特异免疫应答

The Use of Combination Recombinant Polypeptide and DNA Vaccines Against Foot-and-mouth Disease Virus Induces Specific Immune Responses in Guinea Pigs

【结果】PAc多肽抗原微球疫苗口服组的变形链球菌数为（13.2±8.16）×104CFU/ml；磨牙龋齿Keyes计分为31.8±6.77，均显著低于对照组（P<0.01）。

[ Results ] The bacteria numbers of the PAc peptide microparticle group were ( 13.2 ± 8.16 )× 104 CFU / ml and the Keyes scores were 31.8 ± 6.77 . Both were significantly lower than those of the control group ( P < 0.01 ) .

白血病多肽和核酸疫苗研究进展

Advancement of polypeptide and DNA vaccines for leukemia