胞外基质

  • 网络extracellular matrix;ECM;extracellular matrix,ECM
胞外基质胞外基质
  1. 组织金属蛋白酶抑制因子家族(TIMP)是金属蛋白酶(MMP)天然的在组织中的抑制因子,TIMPs与MMPs两大酶系之间的平衡是胞外基质(ECM)稳态的重要条件之一。

    Tissue Inhibitor of Metalloproteinases ( TIMP ) are natural inhibitors of Metalloproteinases in tissues . Maintenance of the balance between TIMPs and MMPs is most important for the homeostasis of ECM .

  2. 钛表面胞外基质涂层对骨髓基质干细胞增殖和分化的影响

    The effect of titanium coated by extracellular matrix from osteoblasts on bone marrow stromal cells ′ growth and differentiation

  3. 结果在实验浓度范围内,两种因子均促进细胞增殖、DNA合成及增加胞外基质中葡萄糖醛酸含量,且呈剂量-效应依赖关系。

    Results Both bFGF and IGF-1 promoted cell proliferation and DNA composition and increased the content of gluconate in the matrix in a dose-dependent fashion .

  4. 整合素(integrin)是介导细胞与细胞、细胞与胞外基质相互作用的一类黏附分子。

    Integrins is one branch of the cell adhesion molecular families .

  5. MMP-2在降解胞外基质过程中是最为重要的MMPs之一。

    MMP-2 is the most important ones in the family of MMPs .

  6. GAG的含量也降至40%左右。结论兔角膜基质细胞经历长期体外培养后,细胞增殖能力和胞外基质表达水平显著下降,逐渐丧失原有的功能。

    Conclusion Corneal stromal cells lost proliferation potential and normal function when cultured in vitro for a long time .

  7. 目的:探讨纤维粘附素(FN)介导的卵巢癌细胞与胞外基质粘附对耐药的影响,并检测细胞粘附耐药时凋亡抑制基因Survivin的表达。

    Objective : To study cell adhesion drug resistance and detect the expression of Survivin in drug resistant ovarian cancer cell mediated by fibronectin .

  8. 1,25(OH)2D3可加强CaB表达,并使胞外基质对45Ca2+摄取量增加1.5倍。

    The results also manifested that 1,25 ( OH ) 2D 3 could enhance the expression of CaB and stimulate calcium uptake into extracellular matrix .

  9. 同位素示踪方法观察1,25(OH)2D3对胞外基质45Ca2+的影响。

    Isotope tracing study was also adopted for observing the effects of 1,25 ( OH ) 2D 3 on calcium uptake into extracellular matrix .

  10. 目的:探讨牙本质胞外基质成分(dentineextracellularmatrixcomponents,DM)对血管内皮细胞增殖的影响。

    AIM : To investigate the effects of isolated preparations of dentine extracellular matrix components ( DM ) on the proliferation of human umbilical vein endothelial cells ( HUVECs ) .

  11. 比较Ⅰ型胶原与胞外基质(Extracellularmatrix,EM)提取物冻干后形成的膜(EM膜)在体外构建人工真皮的能力,以选择一种更有利于人工真皮形成的支架材料。

    Objective To compare the ability of forming artificial dermis between type I and extracellular matrix ( EM ) membranes , and select a more beneficial frame material for the construction of artificial dermis .

  12. 其间,肝星状细胞激活产生大量胞外基质(Extracellularmatrix,ECM)且肝脏中胞外基质降解减少,使肝内胞外基质过量沉积为病理特征。

    The activated hepatic stellate cells produce large quantities of extracellular matrix ( ECM ) and the extracellular matrix in liver degradation reduced . Intrahepatic extracellular matrix excessive deposition is the pathological features of hepatic fibrosis .

  13. 髁突软骨是TMJ改建的中心,具有较强的改建与修复能力,软骨组织通过分泌各种生长因子与细胞因子等调控着软骨细胞的增殖与胞外基质的组成,维持软骨细胞所在环境的稳定。

    The chondrocytes of condyle have the ability of remodeling and repairing , which secret many kinds of growth factors and cytokines to regulate the extracelluar matrix which maintains the environments of chondrocytes .

  14. 结果在单层培养条件下,去分化转化软骨细胞只表达Ⅰ型胶原,而在BAI诱导培养基及离心管聚集体培养下该转化软骨细胞表达丰富的Ⅱ型胶原和大量胞外基质。

    RESULTS : In monolayer culture with ordinary medium , only type ⅰ collagen was expressed in the DTCs , while in aggregate culture with BAI induced medium , massive type ⅱ collagen and extracellular matrix were expressed in the DTCs .

  15. 结果表明利用胞外基质筛选的5min组细胞处于幼稚状态,并有强的克隆形成能力,符合预期的ESC特点。

    The results demonstrate that the cells of 5 minutes group are shown have a slow cell cycle , characteristics of immaturity , and behaving like clonogenic cells in vitro .

  16. 阿拉伯半乳糖蛋白(arabinogalactan-proteins,AGPs)是一类主要分布在细胞表面和胞外基质中的糖蛋白。

    Arabinogalactan-proteins ( AGPs ) are a class of proteoglycans distributed mainly in the cell surfaces and extracellular matrix of most plants .

  17. NELL-1作为一种生长因子,对于骨骼的成正常发育以及骨和软骨细胞分化过程中胞外基质蛋白的产生都非常重要。

    NELL-1 is a growth factor required for normal skeletal development and expression of extracellular matrix proteins required for bone and cartilage cell differentiation .

  18. 三七总皂苷对大鼠肾小球系膜细胞CTGF表达及细胞外基质产生的影响非诺贝特和罗格列酮对高糖培养肾小球系膜细胞胞外基质产生和氧化应激的抑制作用

    The Effects of PNS on Expressions of CTGF and Secretion Of ECM Of Cultured Rat Mesangial Cdis Inhibition of fenofibrate or rosiglitazone on production of extracellular matrix and oxidative stress of glomerular mesangial cells incubated with high concentration of glucose

  19. 细胞生物学和分子生物学的研究表明,MMPs在正常生理调节机制下,能够降解几乎所有胞外基质,参与了多种生理过程,如组织重建、妊娠反应、伤口愈合等。

    As studied by cell biology and molecular biology , with the mechanism of normal physiological modulation , MMPs degrade almost all extracellular matrix ( ECM ) and participate a lot of physiological process , including tissue remodeling , pregnancy , wound healing .

  20. 小鼠胸腺的胞外基质发育

    Development of extracellular matrix in the thymus of balb / c mice

  21. 雌蕊胞外基质在花粉管生长中的作用

    The Pistil Extracellular Matrix and Its Functions in the Pollen Tube Growth

  22. 蛋白多糖和胶原是软骨胞外基质的主要成分。

    Proteoglycan and collagen are main components of cartilage matrix .

  23. 这与肝再生过程中胞外基质重新进行构型的过程有关。

    It is associated with the process of liver regeneration extracellular matrix re-configuration .

  24. 骨髓基质细胞在胞外基质涂层钛表面的黏附和铺展

    Attachment and spreading of bone marrow stromal cells on titanium-coated extracellular matrix from osteoblast

  25. 丙型肝炎病毒核心蛋白对胞外基质金属蛋白酶诱导物基因转录的影响

    Effect of HCV Core Protein on the Gene Transcription of Extracellular Matrix Metalloproteinase Inducer

  26. 牙本质胞外基质对体外血管形成的影响

    Effects of dentin extracellular matrix components on angiogenesis

  27. 牙本质胞外基质对人血管内皮细胞增殖的影响

    Quantitative response of human umbilical vein endothelial cell to extracellular matrix components of dentine

  28. 卵丘细胞及胞外基质诱发中国仓鼠精子顶体反应

    Initiation of the acrosome reaction in Chinese hamster sperm by cumulus oophorus and matrix

  29. 肌腱组织的主要组成是胞外基质中的胶原纤维和镶嵌在胶原纤维内的肌腱细胞。

    Tendons are composed of highly aligned collagen fibrils and elongated fibroblasts known as tenocytes .

  30. Ⅰ型胶原膜、胞外基质提取物膜体外构建人工真皮能力比较

    Comparison Study on the Ability of Forming Artificial Dermis Between Type I and EM Collagen Membranes