痤疮丙酸杆菌

痤疮丙酸杆菌激活的toll样受体

Induction of toll - like receptors by Propionibacterium acnes

厌氧环境下培养痤疮丙酸杆菌并接种于II、III、Ⅳ组金黄地鼠皮脂腺斑，诱导炎症反应产生，1周后进行光动力治疗。

Propionibacterium acnes were cultured and inoculated into II , III , IV golden hamster sebaceous patches to induce inflammatory reaction , 1 week after photodynamic therapy .

不同来源痤疮丙酸杆菌培养上清对THP-1细胞产生TNF-α、IL-12的影响

The influence of different Propionibacterium acnes culture supernatants on the production of TNF - α and IL-12 by THP-1 cells

以红霉素为对照，观察芒果甙对痤疮丙酸杆菌及金黄色葡萄球菌的最小抑菌浓度（MIC）。

The erythromycin was used as control , the minimal inhibitory concentration ( MIC ) of Mangiferin on Propionibacterium Acnes and Staphylocous aureus were observed .

中药体外抑制痤疮丙酸杆菌的活性测定

In vitro antimicrobial activities of traditional Chinese medcine to Propionibacterium acnes

痤疮丙酸杆菌介导的小鼠肝脏肉芽肿疾病模型建立及机制探究

Establishment of Mouse Model of P.acnes-mediated Liver Granuloma and Mechanism Investigation

微生物作用，主要与痤疮丙酸杆菌有关；

Microbial influence , mainly due to propionibacterium ;

对痤疮丙酸杆菌有体外抑制作用；对痤疮患者皮损有良好的修复作用。

It has bacteriostatic action on P.acne , and good recovering effect to acne lesions .

痤疮丙酸杆菌生物膜的构建

The building of biofilm of Propionibacteria acnes

苦参碱对脂多糖／痤疮丙酸杆菌诱导的小鼠肝炎及产生肿瘤坏死因子的影响

Effect of Matrine on mouse hepatitis and TumorNecrosis factor production induced by Propionibacterium acnes / lipopolysaccharides

新疾病外伤后细菌性致死性肉芽肿痤疮丙酸杆菌脑感染的分子生物学及形态学证据

The Molecular Biological and Morphologic Evidence of Pathogen to the New Disease Fatal Bacterial Granuloma after Trauma

观察清螨益肤方外敷药体外杀螨效果及对痤疮丙酸杆菌和白色葡萄球菌的抑菌、杀菌作用。

Observe the anti-mite result of the external application for demodex , propionibacterium acnes and staphylococcus albus .

痤疮丙酸杆菌相关疾病

P. acnes related diseases

结论铜绿假单胞菌和粪肠球菌在模拟胆汁中具有促成核活性，而痤疮丙酸杆菌无促成核作用。

Conclusions Pseudomonas aeruginosa and enTerococcus faecalis , not propionibacterium acne , have pro-nucleating ability in model bile .

其发病机理尚不完全清楚，主要包括：皮脂分泌过多、毛囊皮脂腺导管的过度角化、痤疮丙酸杆菌增殖、过度的免疫反应等。

The pathogenesis is not clear , including : excessive secretion of sebum , follicle sebaceous gland duct hyperkeratosis , Propionibacterium acnes proliferation and excessive immune reactions ect .

结果：1.光动力治疗后皮脂腺斑炎症反应减少与P.lcnes组比较，ALA.PDT和单纯红光照射均能减轻痤疮丙酸杆菌感染引起的以炎细胞浸润为主的炎症性改变。

Photodynamic therapy could reduce the inflammatory reaction . Compared with P.acnes group , ALA-PDT and red light irradiation alone can reduce the monocytes inflammation , which caused by Propionibacterium acnes .

共检出致病菌217株，其中痤疮丙酸杆菌71株（占32.72%），颗粒丙酸杆菌39株（17.97%），其余为葡萄球菌（107株，占49.31%）。

A total of 217 strains of pathogenic bacteria were found including 71 Propionibacterium acne strains ( 32.72 % ), 39 P. granulosum strains ( 17 97 % ) and 107 Staphylococcus strains ( 49.31 % ) .

炎症反应是痤疮发生的重要原因之一，痤疮丙酸杆菌是导致痤疮炎症发生的首要因素，它通过分泌多种促炎症因子，诱导局部炎症反应和机体的免疫反应。

Inflammatory response is one of the main reasons for causing acne . While , as the primary factor leading acne inflammations , propionibacterium acne can induce local inflammatory response and organism immune response by secreting a variety of inflammation prompting factors .