生物素缺乏

结果表明：（1）生物素缺乏可抑制免疫器官的发育，降低其重量指数；

The results showed as follows : ( 1 ) Biotin deficiency impaired the development of immune organs and reduced their weight index .

生物素酶缺乏症的诊断与治疗六例分析

Diagnosis and treatment of biotinidase deficiency-clinical study of six patients

疑难病研究&生物素酶缺乏症

Difficult and complicated case study : biotinidase deficiency

生物素酰胺酶缺乏症：对非结论性新生儿筛选结果进行足够时间随访的重要性

Biotinidase deficiency : The importance of adequate follow-up for an inconclusive newborn screening result

指甲脆弱可能是由于生物素或铁素缺乏，也可能是血液循环问题。

Brittle nails can result from biotin or iron deficiencies and circulation problems .

生物素与生物素酶缺乏症

Biotin and biotinidase deficiency

运用尿气相色谱质谱联用及干燥血液生物素酶活性测定进行筛查，诊断符合生物素酶缺乏症。

Urinary organic acid analysis with gas chromatograph / mass spectrometry and biotinidase activity assay of blood confirmed the diagnosis of biotinidase deficiency .

方法运用尿有机酸分析（气相色谱质谱联用）及干燥滤纸血片生物素酶测定进行筛查与诊断，对6例生物素酶缺乏症患儿的临床经过进行分析。

Methods Six patients aged from 3 months to 14 years with biotinidase deficiency were confirmed by urinary organic acid analysis with gas chromatography / mass spectrometry ( GC / MS ) and biotinidase assay on dried blood spots .