滤过屏障

补充谷氨酰胺对过度训练大鼠肾脏滤过屏障形态结构和尿液成分的影响

Effects of Glutamine and Soybean Peptide Supplementation on the Structure of Kidney Filtration Barrier and Component of Urinary of Over-training Rats

防己黄芪汤治疗肾小球疾病的可能作用机制之一是通过上调CD2AP表达和降低肾组织HPA基因表达水平，修复滤过屏障损伤。

One of the effective mechanism of Fangji Huangqi Decoction is repairing glomerular filtration barrier damage by increasing CD2-associated protein expression and decreasing heparanases expression .

目的：糖胺聚糖（Glycosaminoglycans，GAGs）是肾小球基底膜的主要组成成分，在维持肾小球滤过屏障正常通透性中起重要作用。

Objective : Glycosaminoglycans ( GAGs ) are the major component of the glomerular basement membrane .

肾小球毛细血管的滤过屏障由三层构成：具有窗孔的内皮细胞，肾小球基底膜（GBM），高度分化的脏层上皮细胞（足细胞）及覆盖于GBM表面的足细胞足突。

The glomerular filtration barrier present in the capillary walls is comprised of a fenestrated endothelium , the glomerular basement membrane ( GBM ), and highly specialized visceral epithelial called podocytes , the foot processes of which cover the outer surface of the GBM .

大鼠肾小体发育中滤过屏障超微结构的演变

Changes of ultrastructures of filtration membrane during development of rat renal corpuscle

鱼精蛋白致大鼠肾滤过屏障病变的形态计量研究

Morphometric study of the protamine-induced pathological changes to the kidney filtration barrier in rat

肾小球疾病主要的病理学改变为肾小球滤过屏障受损而导致的蛋白尿。

One of the main pathological changes is proteinuria which caused by glomerular filtration barrier damage .

中华鳖肾小球滤过屏障的形态特征可能与爬行动物具有很低的血管球滤过率相一致。

Morphological characteristics of glomerular filtration barrier may be consistent with the lower reptile glomerular filtration rate .

也是肾小球滤过屏障通透性增高，大量蛋白质漏出的主要病理学基础。

These changes were also the main pathogenic bases of kidney filtration barrier permeability increase and heavy proteinuria .

不同负荷游泳对大鼠肾脏滤过屏障形态结构和功能影响的研究

Effects of Swimming with Different Loads on Modality , Structure and Function of Kidney Filtration Barrier of Rats

当足细胞出现损伤、脱落时，能够引起肾小球滤过屏障的破坏和蛋白尿的发生，导致肾小球进行性硬化。

Podocyte injury causes not only the destruction of the glomerular filtration barrier , but also the formation of proteinuria , leading to glomerular sclerosis .

利用图像分析仪和体视学方法分别对肾小球滤过屏障多价阴离子变化及上皮细胞足突的病变进行形态计量学研究。

The changes of polyanion of the glomerular filtration barrier and the morphological changes of epithelial foot processes were studied using an Image Analyzer and stereological techniques .

肾小球的滤过屏障由毛细血管内皮细胞、基底膜以及足细胞构成，足细胞在肾小球滤过过程中发挥了最关键的作用。

The glomerular filtration barrier consists of capillary endothelial cells , basement membrane and podocytes . Podocytes play a key role in the process of glomerular filtration .

结果表明：胆道梗阻一周即可引起肾小球滤过屏障损害、近曲小管上皮细胞变性。

The results presented that the damage of glomerular filtration membrane had already taken place and , that the epithelial cells of the proximal tubule showed cloudy swelling at 1 week .

血浆经过肾小球滤过屏障超滤形成原尿是肾脏的重要功能之一。肾小球的滤过屏障由带窗孔的内皮细胞、肾小球基底膜以及高度分化的足细胞组成。

Plasma ultrafiltration during primary urine formation is a central function of the kidney , occuring through the glomerular filtration barrier , which is composed of a fenestrated endothelium , the glomerular basement membrane and specialized epithelial cells called podocyte .

目的观察糖脂代谢紊乱对糖尿病大鼠肾小球滤过屏障外层足细胞的影响，以探讨糖尿病肾病的发病机制。

Objective To investigate the influence of glucose and lipid metabolic disorders on podocyte , the last barrier of glomerular filtration , to research the pathogenesis of diabetic nephropathy . Methods Diabetic rats were induced by streptozotocin ( STZ ) .

其发病机制是免疫复合物沉积于肾小球基底膜，激活补体，损伤足细胞，导致肾小球滤过屏障遭到破坏，产生大量的蛋白尿。

The pathogenesis of IMN is because of the thickened basement membrane that resulted from immune complex deposition in the glomerular capillary loop , it can active complement and destroy the podocyte lead to the damage of glomerular filtration membrane , and then lead to massive proteinuria .

近年发现，足细胞在DN的发展过程中起重要作用，足细胞损伤后滤过膜电荷屏障和孔径屏障的破坏，是蛋白尿形成的重要原因。

In recent years , it was found that podocyte play an important role in the development of DN , and podocyte injury can led to the damage of filtration membrane charge barrier and aperture barrier , which is an important reason for the formation of proteinuria .

肾小球是肾脏发挥滤过和排泄功能的主要部位，在某些病理因素的作用下，肾小球的滤过屏障极易受损，导致大分子蛋白质随尿液渗出而形成蛋白尿。

Glomerulus is the most important part of kidney filtration and excretion function . In some clinical pathological cases , the glomerular filtration barrier will be damaged and followed by large proteins leakage and proteinuria .